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Mary Rusckowski PhD

TitleAssociate Professor
InstitutionUMass Chan Medical School
DepartmentRadiology
AddressUMass Chan Medical School
55 Lake Avenue North
Worcester MA 01655
Phone508-856-6972
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentRadiology


    Collapse Biography 
    Collapse education and training
    Albertus Magnus College, New Haven, CT, United StatesBABiology
    Rutgers University Newark, Newark, NJ, United StatesPHDBiochemistry

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. McDonald RC, Fischer AH, Rusckowski M. Oxygen Sensor-Guided Fine Needle Biopsy Studies of Human Cancer Xenografts in Mice. bioRxiv. 2024 Jun 01. PMID: 38854036.
      Citations:    
    2. Ramesh K, Truong A, Wang Y, Rusckowski M, Gkikas M. Ligand-Specific Nano-Contrast Agents Promote Enhanced Breast Cancer CT Detection at 0.5 mg Au. Int J Mol Sci. 2022 Sep 01; 23(17). PMID: 36077324.
      Citations:    Fields:    Translation:Animals
    3. Hsueh YC, Wang Y, Riding RL, Catalano DE, Lu YJ, Richmond JM, Siegel DL, Rusckowski M, Stanley JR, Harris JE. A Keratinocyte-Tethered Biologic Enables Location-Precise Treatment in Mouse Vitiligo. J Invest Dermatol. 2022 12; 142(12):3294-3303. PMID: 35787400.
      Citations: 2     Fields:    Translation:AnimalsCells
    4. Lee PJ, Kennedy Z, Wang Y, Lu Y, Cefaliello C, Uyan ?, Song CQ, Godinho BMC, Xu Z, Rusckowski M, Xue W, Brown RH. Imaging Net Retrograde Axonal Transport In Vivo: A Physiological Biomarker. Ann Neurol. 2022 05; 91(5):716-729. PMID: 35178738.
      Citations: 3     Fields:    Translation:HumansAnimals
    5. Chen L, Cheng D, Liu G, Dou S, Wang Y, Liu X, Liu Y, Rusckowski M. Detection of Klebsiella. Pneumoniae Infection with an Antisense Oligomer Against its Ribosomal RNA. Mol Imaging Biol. 2016 08; 18(4):527-34. PMID: 26832678.
      Citations: 2     Fields:    Translation:AnimalsCells
    6. Rusckowski M, Wang Y, Blankenberg FG, Levashova Z, Backer MV, Backer JM. Targeted scVEGF/(177)Lu radiopharmaceutical inhibits growth of metastases and can be effectively combined with chemotherapy. EJNMMI Res. 2016 Dec; 6(1):4. PMID: 26780081.
      Citations:    
    7. Clear KJ, Harmatys KM, Rice DR, Wolter WR, Suckow MA, Wang Y, Rusckowski M, Smith BD. Phenoxide-Bridged Zinc(II)-Bis(dipicolylamine) Probes for Molecular Imaging of Cell Death. Bioconjug Chem. 2016 Feb 17; 27(2):363-75. PMID: 26334386.
      Citations: 7     Fields:    Translation:AnimalsCells
    8. Li X, Huang Q, Xiao J, Liu G, Dou S, Rusckowski M, Shi H, Liu Y, Cheng D. Novel DNA Polymer for Amplification Pretargeting. ACS Med Chem Lett. 2015 Sep 10; 6(9):972-6. PMID: 26396682.
      Citations:    
    9. Rice DR, Plaunt AJ, Turkyilmaz S, Smith M, Wang Y, Rusckowski M, Smith BD. Evaluation of [???In]-labeled zinc-dipicolylamine tracers for SPECT imaging of bacterial infection. Mol Imaging Biol. 2015 Apr; 17(2):204-13. PMID: 25115869.
      Citations: 8     Fields:    Translation:AnimalsCells
    10. Dou S, Virostko J, Rusckowski M, Greiner DL, Powers AC, Liu G. Differentiation between temporary and real non-clearability of biotinylated IgG antibody by avidin in mice. Front Pharmacol. 2014; 5:172. PMID: 25104938.
      Citations:    
    11. Dou S, Wang Y, Barton B, Chen L, Rusckowski M, Shultz LD, Greiner DL, Liu G. Comparison between two labeled agents in mice using a coinjection-ratio approach in contrast to a conventional group approach. Nucl Med Biol. 2014 Jan; 41(1):127-31. PMID: 24210286.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    12. Chen L, Wang Y, Cheng D, Liu X, Dou S, Liu G, Hnatowich DJ, Rusckowski M. (99m)Tc-MORF oligomers specific for bacterial ribosomal RNA as potential specific infection imaging agents. Bioorg Med Chem. 2013 Nov 01; 21(21):6523-30. PMID: 24054488.
      Citations: 6     Fields:    Translation:AnimalsCells
    13. Sugimoto H, LeBleu VS, Bosukonda D, Keck P, Taduri G, Bechtel W, Okada H, Carlson W, Bey P, Rusckowski M, Tampe B, Tampe D, Kanasaki K, Zeisberg M, Kalluri R. Reply to Regarding the mechanism of action of a proposed peptide agonist of the bone morphogenetic protein receptor activin-like kinase 3. Nat Med. 2013 Jul; 19(7):810-1. PMID: 23836214.
      Citations: 2     Fields:    Translation:Animals
    14. Dou S, Smith M, Wang Y, Rusckowski M, Liu G. Intraperitoneal injection is not always a suitable alternative to intravenous injection for radiotherapy. Cancer Biother Radiopharm. 2013 May; 28(4):335-42. PMID: 23469942.
      Citations: 12     Fields:    Translation:AnimalsCells
    15. Wang Y, Chen L, Liu X, Cheng D, Liu G, Liu Y, Dou S, Hnatowich DJ, Rusckowski M. Detection of Aspergillus fumigatus pulmonary fungal infections in mice with (99m)Tc-labeled MORF oligomers targeting ribosomal RNA. Nucl Med Biol. 2013 Jan; 40(1):89-96. PMID: 23142409.
      Citations: 17     Fields:    Translation:AnimalsCells
    16. Liu X, Nakamura K, Cheng D, Peng C, Xiao N, Liu Y, Chen L, Rusckowski M, Hnatowich DJ. Her2/neu small interfering RNA delivered in culture by a streptavidin nanoparticle. Curr Drug Deliv. 2012 Jul; 9(4):431-6. PMID: 22520071.
      Citations:    Fields:    Translation:HumansCells
    17. Liu X, Cheng D, Gray BD, Wang Y, Akalin A, Rusckowski M, Pak KY, Hnatowich DJ. Radiolabeled Zn-DPA as a potential infection imaging agent. Nucl Med Biol. 2012 Jul; 39(5):709-14. PMID: 22321532.
      Citations: 10     Fields:    Translation:AnimalsCells
    18. Liu G, Dou S, Akalin A, Rusckowski M, Streeter PR, Shultz LD, Greiner DL. Pretargeting vs. direct targeting of human betalox5 islet cells subcutaneously implanted in mice using an anti-human islet cell antibody. Nucl Med Biol. 2012 Jul; 39(5):645-51. PMID: 22316614.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    19. Sugimoto H, LeBleu VS, Bosukonda D, Keck P, Taduri G, Bechtel W, Okada H, Carlson W, Bey P, Rusckowski M, Tampe B, Tampe D, Kanasaki K, Zeisberg M, Kalluri R. Activin-like kinase 3 is important for kidney regeneration and reversal of fibrosis. Nat Med. 2012 Feb 05; 18(3):396-404. PMID: 22306733.
      Citations: 113     Fields:    Translation:AnimalsCells
    20. Liu G, Dou S, Liu Y, Wang Y, Rusckowski M, Hnatowich DJ. 90Y labeled phosphorodiamidate morpholino oligomer for pretargeting radiotherapy. Bioconjug Chem. 2011 Dec 21; 22(12):2539-45. PMID: 21985267.
      Citations: 17     Fields:    Translation:Animals
    21. Chen L, Wang Y, Cheng D, Dou S, Liu X, Liu G, Hnatowich DJ, Rusckowski M. Comparing two TAG-72 binding peptides previously identified by phage display as potential imaging agents. Nucl Med Commun. 2011 Oct; 32(10):920-4. PMID: 21876403.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    22. Liu Y, Cheng D, Liu X, Liu G, Dou S, Xiao N, Chen L, Rusckowski M, Hnatowich DJ. Comparing the intracellular fate of components within a noncovalent streptavidin nanoparticle with covalent conjugation. Nucl Med Biol. 2012 Jan; 39(1):101-7. PMID: 21958854.
      Citations: 5     Fields:    Translation:HumansCells
    23. Liu G, Dou S, Cheng D, Leif J, Rusckowski M, Streeter PR, Shultz LD, Hnatowich DJ, Greiner DL. Human islet cell MORF/cMORF pretargeting in a xenogeneic murine transplant model. Mol Pharm. 2011 Jun 06; 8(3):767-73. PMID: 21361360.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    24. Cheng D, Rusckowski M, Pretorius PH, Chen L, Xiao N, Liu Y, Liu G, Liang M, Liu X, Dou S, Hnatowich DJ. Improving the quantitation accuracy in noninvasive small animal single photon emission computed tomography imaging. Nucl Med Biol. 2011 Aug; 38(6):843-8. PMID: 21843780.
      Citations:    Fields:    Translation:Animals
    25. Hoppin J, Orcutt KD, Hesterman JY, Silva MD, Cheng D, Lackas C, Rusckowski M. Assessing antibody pharmacokinetics in mice with in vivo imaging. J Pharmacol Exp Ther. 2011 May; 337(2):350-8. PMID: 21317355.
      Citations: 15     Fields:    Translation:Animals
    26. Cheng D, Rusckowski M, Wang Y, Liu Y, Liu G, Liu X, Hnatowich D. A brief evaluation of tumor imaging in mice with 99mTc-glucarate including a comparison with 18F-FDG. Curr Radiopharm. 2011 Jan; 4(1):5-9. PMID: 22191610.
      Citations: 1     Fields:    Translation:AnimalsCells
    27. Xiao N, Cheng D, Wang Y, Chen L, Liu X, Dou S, Liu G, Liang M, Hnatowich DJ, Rusckowski M. Identification of a high affinity TAG-72 binding peptide by phage display selection. Cancer Biol Ther. 2011 Jan 01; 11(1):22-31. PMID: 20980835.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    28. Liang M, Liu X, Liu G, Dou S, Cheng D, Liu Y, Rusckowski M, Hnatowich DJ. Reducing the background fluorescence in mice receiving fluorophore/inhibitor DNA duplexes. Mol Pharm. 2011 Feb 07; 8(1):126-32. PMID: 21133414.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    29. Liu G, Dou S, Chen X, Chen L, Liu X, Rusckowski M, Hnatowich DJ. Adding a clearing agent to pretargeting does not lower the tumor accumulation of the effector as predicted. Cancer Biother Radiopharm. 2010 Dec; 25(6):757-62. PMID: 21204772.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    30. Liu G, Dou S, Liu Y, Liang M, Chen L, Cheng D, Greiner D, Rusckowski M, Hnatowich DJ. Unexpected side products in the conjugation of an amine-derivatized morpholino oligomer with p-isothiocyanate benzyl DTPA and their removal. Nucl Med Biol. 2011 Feb; 38(2):159-63. PMID: 21315270.
      Citations: 2     Fields:    Translation:AnimalsCells
    31. Liu G, Dou S, Baker S, Akalin A, Cheng D, Chen L, Rusckowski M, Hnatowich DJ. A preclinical 188Re tumor therapeutic investigation using MORF/cMORF pretargeting and an antiTAG-72 antibody CC49. Cancer Biol Ther. 2010 Oct 15; 10(8):767-74. PMID: 21099368.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    32. Cheng D, Wang Y, Liu X, Pretorius PH, Liang M, Rusckowski M, Hnatowich DJ. Comparison of 18F PET and 99mTc SPECT imaging in phantoms and in tumored mice. Bioconjug Chem. 2010 Aug 18; 21(8):1565-70. PMID: 20681508.
      Citations: 12     Fields:    Translation:Animals
    33. Liang M, Liu X, Cheng D, Liu G, Dou S, Wang Y, Rusckowski M, Hnatowich DJ. Multimodality nuclear and fluorescence tumor imaging in mice using a streptavidin nanoparticle. Bioconjug Chem. 2010 Jul 21; 21(7):1385-8. PMID: 20557066.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    34. Liu X, Nakamura K, Wang Y, Cheng D, Liang M, Xiao N, Chen L, Rusckowski M, Hnatowich DJ. Auger-mediated cytotoxicity of cancer cells in culture by an 125I-antisense oligomer delivered as a three-component streptavidin nanoparticle. J Biomed Nanotechnol. 2010 Apr; 6(2):153-7. PMID: 20738069.
      Citations: 2     Fields:    Translation:HumansCells
    35. Liu G, Dou S, Rusckowski M, Greiner D, Hnatowich D. Preparation of (111)In-DTPA morpholino oligomer for low abdominal accumulation. Appl Radiat Isot. 2010 Sep; 68(9):1709-14. PMID: 20359901.
      Citations: 3     Fields:    Translation:HumansAnimals
    36. Liu G, Dou S, Pretorius PH, Liu X, Chen L, Rusckowski M, Hnatowich DJ. Tumor pretargeting in mice using MORF conjugated CC49 antibody and radiolabeled complimentary cMORF effector. Q J Nucl Med Mol Imaging. 2010 Jun; 54(3):333-40. PMID: 20639818.
      Citations: 16     Fields:    Translation:Animals
    37. Wang Y, Liu X, Chen L, Cheng D, Rusckowski M, Hnatowich DJ. Tumor delivery of antisense oligomer using trastuzumab within a streptavidin nanoparticle. Eur J Nucl Med Mol Imaging. 2009 Dec; 36(12):1977-86. PMID: 19572130.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    38. Liu G, Dou S, Liang M, Chen X, Rusckowski M, Hnatowich DJ. The ratio of maximum percent tumour accumulations of the pretargeting agent and the radiolabelled effector is independent of tumour size. Eur J Cancer. 2009 Nov; 45(17):3098-103. PMID: 19811906.
      Citations: 9     Fields:    Translation:Animals
    39. Wang Y, Liu X, Nakamura K, Chen L, Rusckowski M, Hnatowich DJ. In vivo delivery of antisense MORF oligomer by MORF/carrier streptavidin nanoparticles. Cancer Biother Radiopharm. 2009 Oct; 24(5):573-8. PMID: 19877887.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    40. Liang M, Liu X, Cheng D, Nakamura K, Wang Y, Dou S, Liu G, Rusckowski M, Hnatowich DJ. Optical antisense tumor targeting in vivo with an improved fluorescent DNA duplex probe. Bioconjug Chem. 2009 Jun; 20(6):1223-7. PMID: 19489604.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    41. Liang M, Liu X, Nakamura K, Chen X, Cheng D, Liu G, Dou S, Wang Y, Rusckowski M, Hnatowich DJ. A convenient thiazole orange fluorescence assay for the evaluation of DNA duplex hybridization stability. Mol Imaging Biol. 2009 Nov-Dec; 11(6):439-45. PMID: 19444399.
      Citations: 1     Fields:    Translation:AnimalsCells
    42. Liu G, Cheng D, Dou S, Chen X, Liang M, Pretorius PH, Rusckowski M, Hnatowich DJ. Replacing 99mTc with 111In improves MORF/cMORF pretargeting by reducing intestinal accumulation. Mol Imaging Biol. 2009 Sep-Oct; 11(5):303-7. PMID: 19326173.
      Citations: 12     Fields:    Translation:Animals
    43. Liu X, Wang Y, Nakamura K, Kawauchi S, Akalin A, Cheng D, Chen L, Rusckowski M, Hnatowich DJ. Auger radiation-induced, antisense-mediated cytotoxicity of tumor cells using a 3-component streptavidin-delivery nanoparticle with 111In. J Nucl Med. 2009 Apr; 50(4):582-90. PMID: 19289423.
      Citations: 7     Fields:    Translation:AnimalsCells
    44. Chen L, Wang Y, Liu X, Dou S, Liu G, Hnatowich DJ, Rusckowski M. A new TAG-72 cancer marker peptide identified by phage display. Cancer Lett. 2008 Dec 08; 272(1):122-32. PMID: 18723274.
      Citations: 14     Fields:    Translation:HumansCells
    45. Chen X, Dou S, Liu G, Liu X, Wang Y, Chen L, Rusckowski M, Hnatowich DJ. Synthesis and in vitro characterization of a dendrimer-MORF conjugate for amplification pretargeting. Bioconjug Chem. 2008 Aug; 19(8):1518-25. PMID: 18646837.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    46. Liu G, Dou S, Rusckowski M, Hnatowich DJ. An experimental and theoretical evaluation of the influence of pretargeting antibody on the tumor accumulation of effector. Mol Cancer Ther. 2008 May; 7(5):1025-32. PMID: 18483292.
      Citations: 11     Fields:    Translation:AnimalsCells
    47. Kleine LG, Solano M, Rusckowski M, Hunt KE, Johnson KL, Kirker-Head CA. Evaluation of technetium Tc 99m-labeled biotin for scintigraphic detection of soft tissue inflammation in horses. Am J Vet Res. 2008 May; 69(5):639-46. PMID: 18447795.
      Citations:    Fields:    Translation:Animals
    48. Rusckowski M, Gupta S, Liu G, Dou S, Hnatowich DJ. Investigation of four (99m)Tc-labeled bacteriophages for infection-specific imaging. Nucl Med Biol. 2008 May; 35(4):433-40. PMID: 18482680.
      Citations: 13     Fields:    Translation:AnimalsCells
    49. Liu X, Wang Y, Nakamura K, Liu G, Dou S, Kubo A, Rusckowski M, Hnatowich DJ. Optical antisense imaging of tumor with fluorescent DNA duplexes. Bioconjug Chem. 2007 Nov-Dec; 18(6):1905-11. PMID: 17939728.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    50. Liu G, Dou S, Pretorius PH, Liu X, Rusckowski M, Hnatowich DJ. Pretargeting CWR22 prostate tumor in mice with MORF-B72.3 antibody and radiolabeled cMORF. Eur J Nucl Med Mol Imaging. 2008 Feb; 35(2):272-80. PMID: 17909792.
      Citations: 14     Fields:    Translation:AnimalsCells
    51. Rusckowski M, Gupta S, Liu G, Dou S, Hnatowich DJ. Evidence of specificity of radiolabeled phage display peptides for the TAG-72 antigen. Cancer Biother Radiopharm. 2007 Aug; 22(4):564-72. PMID: 17803452.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    52. Zhang S, Liu G, Liu X, Yin D, Dou S, He J, Rusckowski M, Hnatowich DJ. Comparison of several linear fluorophore- and quencher-conjugated oligomer duplexes for stability, fluorescence quenching, and kinetics in vitro and in vivo in mice. Bioconjug Chem. 2007 Jul-Aug; 18(4):1170-5. PMID: 17511492.
      Citations:    Fields:    Translation:Animals
    53. He J, Liu G, Dou S, Gupta S, Rusckowski M, Hnatowich D. An improved method for covalently conjugating morpholino oligomers to antitumor antibodies. Bioconjug Chem. 2007 May-Jun; 18(3):983-8. PMID: 17385902.
      Citations: 23     Fields:    Translation:HumansAnimals
    54. Liu G, Dou S, Yin D, Squires S, Liu X, Wang Y, Rusckowski M, Hnatowich DJ. A novel pretargeting method for measuring antibody internalization in tumor cells. Cancer Biother Radiopharm. 2007 Feb; 22(1):33-9. PMID: 17461727.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    55. Liu G, Dou S, He J, Liu X, Rusckowski M, Hnatowich DJ. Predicting the biodistribution of radiolabeled cMORF effector in MORF-pretargeted mice. Eur J Nucl Med Mol Imaging. 2007 Feb; 34(2):237-46. PMID: 17021815.
      Citations: 14     Fields:    Translation:AnimalsCells
    56. He J, Rusckowski M, Wang Y, Dou S, Liu X, Zhang S, Liu G, Hnatowich DJ. Optical pretargeting of tumor with fluorescent MORF oligomers. Mol Imaging Biol. 2007 Jan-Feb; 9(1):17-23. PMID: 17171474.
      Citations: 5     Fields:    Translation:Animals
    57. Wang Y, Liu X, Zhang Y, Liu G, Rusckowski M, Hnatowich DJ. Nonspecific cellular accumulation of 99mTc-labeled oligonucleotides in culture is influenced by their guanine content. Nucl Med Biol. 2007 Jan; 34(1):47-54. PMID: 17210461.
      Citations: 2     Fields:    Translation:HumansCells
    58. Liu X, Nakamura K, Wang Y, Zhang S, He J, Liu G, Dou S, Kubo A, Rusckowski M, Hnatowich D. Improved delivery in cell culture of radiolabeled antisense DNAs by duplex formation. Mol Imaging Biol. 2006 Sep-Oct; 8(5):278-83. PMID: 16924429.
      Citations: 1     Fields:    Translation:HumansCells
    59. Liu G, Dou S, Mardirossian G, He J, Zhang S, Liu X, Rusckowski M, Hnatowich DJ. Successful radiotherapy of tumor in pretargeted mice by 188Re-radiolabeled phosphorodiamidate morpholino oligomer, a synthetic DNA analogue. Clin Cancer Res. 2006 Aug 15; 12(16):4958-64. PMID: 16914585.
      Citations: 21     Fields:    Translation:Animals
    60. Liu G, Dou S, He J, Yin D, Gupta S, Zhang S, Wang Y, Rusckowski M, Hnatowich DJ. Radiolabeling of MAG3-morpholino oligomers with 188Re at high labeling efficiency and specific radioactivity for tumor pretargeting. Appl Radiat Isot. 2006 Sep; 64(9):971-8. PMID: 16730997.
      Citations: 29     Fields:    Translation:Animals
    61. Liu X, Nakamura K, Wang Y, Wang Y, Liu G, He J, Ding H, Lu P, Rusckowski M, Kubo A, Hnatowich DJ. Initial mechanistic studies of antisense targeting in cells. J Nucl Med. 2006 Feb; 47(2):360-8. PMID: 16455644.
      Citations: 3     Fields:    Translation:HumansCells
    62. Zhang YM, Tung CH, He J, Liu N, Yanachkov I, Liu G, Rusckowski M, Vanderheyden JL. Construction of a novel chimera consisting of a chelator-containing Tat peptide conjugated to a morpholino antisense oligomer for technetium-99m labeling and accelerating cellular kinetics. Nucl Med Biol. 2006 Feb; 33(2):263-9. PMID: 16546682.
      Citations: 3     Fields:    Translation:HumansCells
    63. Liu G, He J, Dou S, Gupta S, Rusckowski M, Hnatowich DJ. Further investigations of morpholino pretargeting in mice--establishing quantitative relations in tumor. Eur J Nucl Med Mol Imaging. 2005 Sep; 32(9):1115-23. PMID: 16133391.
      Citations: 27     Fields:    Translation:Animals
    64. Liu G, Dou S, He J, Vanderheyden JL, Rusckowski M, Hnatowich DJ. Preparation and properties of 99mTc(CO)3+-labeled N,N-bis(2-pyridylmethyl)-4-aminobutyric acid. Bioconjug Chem. 2004 Nov-Dec; 15(6):1441-6. PMID: 15546213.
      Citations: 8     Fields:    Translation:Animals
    65. Nakamura K, Fan C, Liu G, Gupta S, He J, Dou S, Kubo A, Rusckowski M, Hnatowich DJ. Evidence of antisense tumor targeting in mice. Bioconjug Chem. 2004 Nov-Dec; 15(6):1475-80. PMID: 15546217.
      Citations: 8     Fields:    Translation:AnimalsCells
    66. Zhang Y, He J, Liu G, Venderheyden JL, Gupta S, Rusckowski M, Hnatowich DJ. Initial observations of 99mTc labelled locked nucleic acids for antisense targeting. Nucl Med Commun. 2004 Nov; 25(11):1113-8. PMID: 15577590.
      Citations: 5     Fields:    Translation:HumansCells
    67. He J, Liu C, Vanderheyden JL, Liu G, Dou S, Rusckowski M, Hnatowich DJ. Radiolabelling morpholinos with 188Re tricarbonyl provides improved in vitro and in vivo stability to re-oxidation. Nucl Med Commun. 2004 Jul; 25(7):731-6. PMID: 15208502.
      Citations: 4     Fields:    Translation:AnimalsCells
    68. Rusckowski M, Gupta S, Liu G, Dou S, Hnatowich DJ. Investigations of a (99m)Tc-labeled bacteriophage as a potential infection-specific imaging agent. J Nucl Med. 2004 Jul; 45(7):1201-8. PMID: 15235067.
      Citations: 17     Fields:    Translation:AnimalsCells
    69. He J, Liu G, Gupta S, Zhang Y, Rusckowski M, Hnatowich DJ. Amplification targeting: a modified pretargeting approach with potential for signal amplification-proof of a concept. J Nucl Med. 2004 Jun; 45(6):1087-95. PMID: 15181145.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    70. Liu G, He J, Dou S, Gupta S, Vanderheyden JL, Rusckowski M, Hnatowich DJ. Pretargeting in tumored mice with radiolabeled morpholino oligomer showing low kidney uptake. Eur J Nucl Med Mol Imaging. 2004 Mar; 31(3):417-24. PMID: 14691611.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    71. He J, Liu G, Zhang S, Rusckowski M, Hnatowich DJ. Pharmacokinetics in mice of four oligomer-conjugated polymers for amplification targeting. Cancer Biother Radiopharm. 2003 Dec; 18(6):941-7. PMID: 14969606.
      Citations: 5     Fields:    Translation:Animals
    72. He J, Liu G, Zhang S, Vanderheyden JL, Liu N, Liu C, Zhang Y, Gupta S, Rusckowski M, Hnatowich DJ. A comparison of in vitro and in vivo stability in mice of two morpholino duplexes differing in chain length. Bioconjug Chem. 2003 Sep-Oct; 14(5):1018-23. PMID: 13129406.
      Citations: 5     Fields:    Translation:Animals
    73. Ferro-Flores G, Arteaga de Murphy C, Pedraza-L?pez M, Mel?ndez-Alafort L, Zhang YM, Rusckowski M, Hnatowich DJ. In vitro and in vivo assessment of 99mTc-UBI specificity for bacteria. Nucl Med Biol. 2003 Aug; 30(6):597-603. PMID: 12900285.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    74. Zhang YM, Liu CB, Liu N, Ferro Flores G, He J, Rusckowski M, Hnatowich DJ. Electrostatic binding with tat and other cationic peptides increases cell accumulation of 99mTc-antisense DNAs without entrapment. Mol Imaging Biol. 2003 Jul-Aug; 5(4):240-7. PMID: 14499139.
      Citations: 3     Fields:    
    75. Liu G, Liu C, Zhang S, He J, Liu N, Gupta S, Rusckowski M, Hnatowich DJ. Investigations of 99mTc morpholino pretargeting in mice. Nucl Med Commun. 2003 Jun; 24(6):697-705. PMID: 12766607.
      Citations: 18     Fields:    Translation:Animals
    76. Su ZF, He J, Rusckowski M, Hnatowich DJ. In vitro cell studies of technetium-99m labeled RGD-HYNIC peptide, a comparison of tricine and EDDA as co-ligands. Nucl Med Biol. 2003 Feb; 30(2):141-9. PMID: 12623113.
      Citations: 7     Fields:    Translation:HumansCells
    77. Liu CB, Liu GZ, Liu N, Zhang YM, He J, Rusckowski M, Hnatowich DJ. Radiolabeling morpholinos with 90Y, 111In, 188Re and 99mTc. Nucl Med Biol. 2003 Feb; 30(2):207-14. PMID: 12623121.
      Citations: 11     Fields:    Translation:HumansAnimals
    78. Liu G, He J, Zhang S, Liu C, Rusckowski M, Hnatowich DJ. Cytosine residues influence kidney accumulations of 99mTc-labeled morpholino oligomers. Antisense Nucleic Acid Drug Dev. 2002 Dec; 12(6):393-8. PMID: 12568313.
      Citations: 14     Fields:    Translation:Animals
    79. Liu G, Zhang S, He J, Liu N, Gupta S, Rusckowski M, Hnatowich DJ. The influence of chain length and base sequence on the pharmacokinetic behavior of 99mTc-morpholinos in mice. Q J Nucl Med. 2002 Sep; 46(3):233-43. PMID: 12134139.
      Citations: 19     Fields:    Translation:AnimalsCells
    80. Liu G, Zhang S, He J, Zhu Z, Rusckowski M, Hnatowich DJ. Improving the labeling of S-acetyl NHS-MAG(3)-conjugated morpholino oligomers. Bioconjug Chem. 2002 Jul-Aug; 13(4):893-7. PMID: 12121147.
      Citations: 14     Fields:    
    81. Su ZF, Liu G, Gupta S, Zhu Z, Rusckowski M, Hnatowich DJ. In vitro and in vivo evaluation of a Technetium-99m-labeled cyclic RGD peptide as a specific marker of alpha(V)beta(3) integrin for tumor imaging. Bioconjug Chem. 2002 May-Jun; 13(3):561-70. PMID: 12009947.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    82. Liu G, Mang'era K, Liu N, Gupta S, Rusckowski M, Hnatowich DJ. Tumor pretargeting in mice using (99m)Tc-labeled morpholino, a DNA analog. J Nucl Med. 2002 Mar; 43(3):384-91. PMID: 11884499.
      Citations: 41     Fields:    Translation:AnimalsCells
    83. Liu G, Wescott C, Sato A, Wang Y, Liu N, Zhang YM, Rusckowski M, Hnatowich DJ. Nitriles form mixed-coligand complexes with (99m)Tc-HYNIC-peptide. Nucl Med Biol. 2002 Jan; 29(1):107-13. PMID: 11786281.
      Citations: 4     Fields:    Translation:Animals
    84. Rusckowski M, Qu T, Gupta S, Ley A, Hnatowich DJ. A comparison in monkeys of (99m)Tc labeled to a peptide by 4 methods. J Nucl Med. 2001 Dec; 42(12):1870-7. PMID: 11752087.
      Citations: 9     Fields:    Translation:Animals
    85. Zhang YM, Wang Y, Liu N, Zhu ZH, Rusckowski M, Hnatowich DJ. In vitro investigations of tumor targeting with (99m)Tc-labeled antisense DNA. J Nucl Med. 2001 Nov; 42(11):1660-9. PMID: 11696636.
      Citations: 7     Fields:    Translation:HumansCells
    86. Mang'era KO, Liu G, Yi W, Zhang Y, Liu N, Gupta S, Rusckowski M, Hnatowich DJ. Initial investigations of 99mTc-labeled morpholinos for radiopharmaceutical applications. Eur J Nucl Med. 2001 Nov; 28(11):1682-9. PMID: 11702111.
      Citations: 13     Fields:    Translation:HumansAnimals
    87. Zhang YM, Rusckowski M, Liu N, Liu C, Hnatowich DJ. Cationic liposomes enhance cellular/nuclear localization of 99mTc-antisense oligonucleotides in target tumor cells. Cancer Biother Radiopharm. 2001 Oct; 16(5):411-9. PMID: 11776758.
      Citations: 7     Fields:    Translation:Cells
    88. Wang Y, Chang F, Zhang Y, Liu N, Liu G, Gupta S, Rusckowski M, Hnatowich DJ. Pretargeting with amplification using polymeric peptide nucleic acid. Bioconjug Chem. 2001 Sep-Oct; 12(5):807-16. PMID: 11562199.
      Citations: 18     Fields:    Translation:AnimalsCells
    89. Zhu Z, Wang Y, Zhang Y, Liu G, Liu N, Rusckowski M, Hnatowich DJ. A novel and simplified route to the synthesis of N3S chelators for 99mTc labeling. Nucl Med Biol. 2001 Aug; 28(6):703-8. PMID: 11518652.
      Citations: 2     Fields:    Translation:Animals
    90. Qu T, Wang Y, Zhu Z, Rusckowski M, Hnatowich DJ. Different chelators and different peptides together influence the in vitro and mouse in vivo properties of 99Tcm. Nucl Med Commun. 2001 Feb; 22(2):203-15. PMID: 11258408.
      Citations: 6     Fields:    Translation:AnimalsCells
    91. Zhang YM, Liu N, Zhu ZH, Rusckowski M, Hnatowich DJ. Influence of different chelators (HYNIC, MAG3 and DTPA) on tumor cell accumulation and mouse biodistribution of technetium-99m labeled to antisense DNA. Eur J Nucl Med. 2000 Nov; 27(11):1700-7. PMID: 11105827.
      Citations: 16     Fields:    Translation:AnimalsCells
    92. Rusckowski M, Qu T, Roskey A, Agrawal S. Biodistribution and metabolism of a mixed backbone oligonucleotide (GEM 231) following single and multiple dose administration in mice. Antisense Nucleic Acid Drug Dev. 2000 Oct; 10(5):333-45. PMID: 11079573.
      Citations: 7     Fields:    Translation:Animals
    93. Rusckowski M, Qu T, Pullman J, Marcel R, Ley AC, Ladner RC, Hnatowich DJ. Inflammation and infection imaging with a 99mTc-neutrophil elastase inhibitor in monkeys. J Nucl Med. 2000 Feb; 41(2):363-74. PMID: 10688123.
      Citations: 8     Fields:    Translation:HumansAnimals
    94. Hnatowich DJ, Chang F, Qu T, Rusckowski M. Technetium-99m labeled peptides--an investigation of multiple HPLC peaks. Appl Radiat Isot. 1999 May; 50(5):911-21. PMID: 10214710.
      Citations: 1     Fields:    Translation:Humans
    95. Chang F, Qu T, Rusckowski M, Hnatowich DJ. NHS-MAS3: a bifunctional chelator alternative to NHS-MAG3. Appl Radiat Isot. 1999 Apr; 50(4):723-32. PMID: 10101833.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    96. Fogarasi M, Pullman J, Winnard P, Hnatowich DJ, Rusckowski M. Pretargeting of bacterial endocarditis in rats with streptavidin and 111In-labeled biotin. J Nucl Med. 1999 Mar; 40(3):484-90. PMID: 10086715.
      Citations: 3     Fields:    Translation:Animals
    97. Hnatowich DJ, Qu T, Chang F, Ley AC, Ladner RC, Rusckowski M. Labeling peptides with technetium-99m using a bifunctional chelator of a N-hydroxysuccinimide ester of mercaptoacetyltriglycine. J Nucl Med. 1998 Jan; 39(1):56-64. PMID: 9443739.
      Citations: 10     Fields:    Translation:HumansAnimals
    98. Rusckowski M, Qu T, Chang F, Hnatowich DJ. Pretargeting using peptide nucleic acid. Cancer. 1997 Dec 15; 80(12 Suppl):2699-705. PMID: 9406727.
      Citations: 16     Fields:    Translation:Animals
    99. Chang F, Rusckowski M, Qu T, Hnatowich DJ. Early results in the irrational design of new bifunctional chelators. Cancer. 1997 Dec 15; 80(12 Suppl):2347-53. PMID: 9406682.
      Citations: 2     Fields:    Translation:Humans
    100. Rusckowski M, Qu T, Chang F, Hnatowich DJ. Technetium-99m labeled epidermal growth factor-tumor imaging in mice. J Pept Res. 1997 Nov; 50(5):393-401. PMID: 9401925.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    101. Winnard P, Chang F, Rusckowski M, Mardirossian G, Hnatowich DJ. Preparation and use of NHS-MAG3 for technetium-99m labeling of DNA. Nucl Med Biol. 1997 Jul; 24(5):425-32. PMID: 9290078.
      Citations: 27     Fields:    
    102. Mardirossian G, Lei K, Rusckowski M, Chang F, Qu T, Egholm M, Hnatowich DJ. In vivo hybridization of technetium-99m-labeled peptide nucleic acid (PNA). J Nucl Med. 1997 Jun; 38(6):907-13. PMID: 9189140.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    103. Hnatowich DJ, Chang F, Lei K, Qu T, Rusckowski M. The influence of temperature and alkaline pH on the labeling of free and conjugated MAG3 with technetium-99m. Appl Radiat Isot. 1997 May; 48(5):587-94. PMID: 9204521.
      Citations: 3     Fields:    
    104. Rusckowski M, Fogarasi M, Fritz B, Hnatowich DJ. Effect of endogenous biotin on the applications of streptavidin and biotin in mice. Nucl Med Biol. 1997 Apr; 24(3):263-8. PMID: 9228661.
      Citations: 9     Fields:    Translation:Animals
    105. Rusckowski M, Paganelli G, Hnatowich DJ, Magnani P, Virzi F, Fogarasi M, DiLeo C, Sudati F, Fazio F. Imaging osteomyelitis with streptavidin and indium-111-labeled biotin. J Nucl Med. 1996 Oct; 37(10):1655-62. PMID: 8862303.
      Citations: 4     Fields:    Translation:Humans
    106. Lei K, Rusckowski M, Chang F, Qu T, Mardirossian G, Hnatowich DJ. Technetium-99m antibodies labeled with MAG3 and SHNH: an in vitro and animal in vivo comparison. Nucl Med Biol. 1996 Oct; 23(7):917-22. PMID: 8971860.
      Citations: 3     Fields:    Translation:Animals
    107. Winnard P, Virzi E, Fogarasi M, Rusckowski M, Hnatowich DJ. Investigations of directly labeling antibodies with rhenium-188. Q J Nucl Med. 1996 Jun; 40(2):151-60. PMID: 8909100.
      Citations: 2     Fields:    Translation:AnimalsCells
    108. Hnatowich DJ, Mardirossian G, Rusckowski M, Winnard P. Protein labelling via deoxyribonucleic acid hybridization. Nucl Med Commun. 1996 Jan; 17(1):66-75. PMID: 8692476.
      Citations:    Fields:    Translation:AnimalsCells
    109. Hnatowich DJ, Mardirossian G, Fogarasi M, Sano T, Smith CL, Cantor CR, Rusckowski M, Winnard P. Comparative properties of a technetium-99m-labeled single-stranded natural DNA and a phosphorothioate derivative in vitro and in mice. J Pharmacol Exp Ther. 1996 Jan; 276(1):326-34. PMID: 8558450.
      Citations: 7     Fields:    Translation:AnimalsCells
    110. Hnatowich DJ, Winnard P, Virzi F, Fogarasi M, Sano T, Smith CL, Cantor CR, Rusckowski M. Technetium-99m labeling of DNA oligonucleotides. J Nucl Med. 1995 Dec; 36(12):2306-14. PMID: 8523124.
      Citations: 11     Fields:    Translation:AnimalsCells
    111. Virzi F, Winnard P, Fogarasi M, Sano T, Smith CL, Cantor CR, Rusckowski M, Hnatowich DJ. Recombinant metallothionein-conjugated streptavidin labeled with 188Re and 99mTc. Bioconjug Chem. 1995 Jan-Feb; 6(1):139-44. PMID: 7711101.
      Citations: 2     Fields:    Translation:Animals
    112. Rusckowski M, Fogarasi M, Virzi F, Hnatowich DJ. Influence of endogenous biotin on the biodistribution of labelled biotin derivatives in mice. Nucl Med Commun. 1995 Jan; 16(1):38-46. PMID: 7609933.
      Citations: 3     Fields:    Translation:Animals
    113. Hnatowich DJ, Virzi F, Fogarasi M, Rusckowski M, Winnard P. Can a cysteine challenge assay predict the in vivo behavior of 99mTc-labeled antibodies? Nucl Med Biol. 1994 Nov; 21(8):1035-44. PMID: 9234361.
      Citations: 7     Fields:    Translation:Animals
    114. Hnatowich DJ, Virzi F, Winnard P, Fogarasi M, Rusckowski M. Investigations of ascorbate for direct labeling of antibodies with technetium-99m. J Nucl Med. 1994 Jan; 35(1):127-34. PMID: 8271033.
      Citations: 1     Fields:    
    115. Hnatowich DJ, Fritz B, Virzi F, Mardirossian G, Rusckowski M. Improved tumor localization with (strept)avidin and labeled biotin as a substitute for antibody. Nucl Med Biol. 1993 Feb; 20(2):189-95. PMID: 8448574.
      Citations: 6     Fields:    Translation:Animals
    116. Hnatowich DJ, Mardirossian G, Rusckowski M, Fogarasi M, Virzi F, Winnard P. Directly and indirectly technetium-99m-labeled antibodies--a comparison of in vitro and animal in vivo properties. J Nucl Med. 1993 Jan; 34(1):109-19. PMID: 8418250.
      Citations: 7     Fields:    Translation:Animals
    117. Hnatowich DJ, Mardirossian G, Rusckowski M, Roy S, Bushe H, Griffin TW, Brill AB. Pharmacokinetics of the FO23C5 anti-CEA antibody fragment labelled with 99Tcm and 111In: a comparison in patients. Nucl Med Commun. 1993 Jan; 14(1):52-63. PMID: 8423936.
      Citations: 1     Fields:    Translation:Humans
    118. Rusckowski M, Fritz B, Hnatowich DJ. Localization of infection using streptavidin and biotin: an alternative to nonspecific polyclonal immunoglobulin. J Nucl Med. 1992 Oct; 33(10):1810-5. PMID: 1403148.
      Citations: 11     Fields:    Translation:Animals
    119. Mardirossian G, Wu C, Rusckowski M, Hnatowich DJ. The stability of 99Tcm directly labelled to an Fab' antibody via stannous ion and mercaptoethanol reduction. Nucl Med Commun. 1992 Jul; 13(7):503-12. PMID: 1495677.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    120. Hnatowich DJ, Rusckowski M, Siebecker DA, Gionet M, Mardirossian G, Bushe HS, Roy S, Mattis JA, Shealy D, Griffin TW, et al. Pharmacokinetics of indium-111 labeled 10-3D2 antibreast-tumor antibody in patients. J Nucl Biol Med (1991). 1992 Jan-Mar; 36(1):7-13. PMID: 1450229.
      Citations: 1     Fields:    Translation:Humans
    121. Griffin TW, Brill AB, Stevens S, Collins JA, Bokhari F, Bushe H, Stochl MC, Gionet M, Rusckowski M, Stroupe SD, et al. Initial clinical study of indium-111-labeled clone 110 anticarcinoembryonic antigen antibody in patients with colorectal cancer. J Clin Oncol. 1991 Apr; 9(4):631-40. PMID: 2066759.
      Citations: 3     Fields:    Translation:Humans
    122. Virzi F, Fritz B, Rusckowski M, Gionet M, Misra H, Hnatowich DJ. New indium-111 labeled biotin derivatives for improved immunotargeting. Int J Rad Appl Instrum B. 1991; 18(7):719-26. PMID: 1787080.
      Citations: 1     Fields:    Translation:AnimalsCells
    123. Hnatowich DJ, Rusckowski M, Brill AB, Siebecker DA, Misra H, Mardirossian G, Bushe H, Rescigno A, Stevens S, Johnson DK, et al. Pharmacokinetics in patients of an anti-carcinoembryonic antigen antibody radiolabeled with indium-111 using a novel diethylenetriamine pentaacetic acid chelator. Cancer Res. 1990 Nov 15; 50(22):7272-8. PMID: 2224858.
      Citations: 6     Fields:    Translation:Humans
    124. Kalofonos HP, Rusckowski M, Siebecker DA, Sivolapenko GB, Snook D, Lavender JP, Epenetos AA, Hnatowich DJ. Imaging of tumor in patients with indium-111-labeled biotin and streptavidin-conjugated antibodies: preliminary communication. J Nucl Med. 1990 Nov; 31(11):1791-6. PMID: 2230992.
      Citations: 24     Fields:    Translation:HumansCTClinical Trials
    125. Rescigno A, Bushe H, Brill AB, Rusckowski M, Griffin TW, Hnatowich DJ. Pharmacokinetic modeling of radiolabeled antibody distribution in man. Am J Physiol Imaging. 1990; 5(4):141-50. PMID: 2090165.
      Citations:    Fields:    Translation:Humans
    126. Hnatowich DJ, Gionet M, Rusckowski M, Siebecker DA, Roche J, Shealy D, Mattis JA, Wilson J, McGann J, Hunter RE, et al. Pharmacokinetics of 111In-labeled OC-125 antibody in cancer patients compared with the 19-9 antibody. Cancer Res. 1987 Nov 15; 47(22):6111-7. PMID: 3664510.
      Citations: 11     Fields:    Translation:Humans
    127. Hnatowich DJ, Virzi F, Rusckowski M. Investigations of avidin and biotin for imaging applications. J Nucl Med. 1987 Aug; 28(8):1294-302. PMID: 3612292.
      Citations: 89     Fields:    Translation:Animals
    128. Hnatowich DJ, Griffin TW, Kosciuczyk C, Rusckowski M, Childs RL, Mattis JA, Shealy D, Doherty PW. Pharmacokinetics of an indium-111-labeled monoclonal antibody in cancer patients. J Nucl Med. 1985 Aug; 26(8):849-58. PMID: 3861793.
      Citations: 21     Fields:    Translation:HumansCells
    129. Rusckowski M, Doherty PW, Virzi F, Hnatowich DJ. A simple in vitro method of screening panels of monoclonal antibodies for tumor binding. J Immunol Methods. 1985 Feb 11; 76(2):375-82. PMID: 3973393.
      Citations: 1     Fields:    Translation:HumansCells
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