Interleukin-21 Receptor alpha Subunit
"Interleukin-21 Receptor alpha Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An interleukin-21 receptor subunit that combines with the INTERLEUKIN RECEPTOR COMMON GAMMA SUBUNIT to form a high affinity receptor for interleukin-21. It signals via interaction of its cytoplasmic domain with JANUS KINASES such as JANUS KINASE 1 and JANUS KINASE 3.
| Descriptor ID |
D053738
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| MeSH Number(s) |
D12.776.543.750.705.852.420.900.450
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| Concept/Terms |
Interleukin-21 Receptor alpha Subunit- Interleukin-21 Receptor alpha Subunit
- Interleukin 21 Receptor alpha Subunit
- IL-21 Receptor alpha Chain
- IL 21 Receptor alpha Chain
- Interleukin-21 Receptor alpha Chain
- Interleukin 21 Receptor alpha Chain
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Below are MeSH descriptors whose meaning is more general than "Interleukin-21 Receptor alpha Subunit".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-21 Receptor alpha Subunit".
This graph shows the total number of publications written about "Interleukin-21 Receptor alpha Subunit" by people in this website by year, and whether "Interleukin-21 Receptor alpha Subunit" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Interleukin-21 Receptor alpha Subunit" by people in Profiles.
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Brodeur TY, Robidoux TE, Weinstein JS, Craft J, Swain SL, Marshak-Rothstein A. IL-21 Promotes Pulmonary Fibrosis through the Induction of Profibrotic CD8+ T Cells. J Immunol. 2015 Dec 01; 195(11):5251-60.
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Pesce J, Kaviratne M, Ramalingam TR, Thompson RW, Urban JF, Cheever AW, Young DA, Collins M, Grusby MJ, Wynn TA. The IL-21 receptor augments Th2 effector function and alternative macrophage activation. J Clin Invest. 2006 Jul; 116(7):2044-55.
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Ma HL, Whitters MJ, Konz RF, Senices M, Young DA, Grusby MJ, Collins M, Dunussi-Joannopoulos K. IL-21 activates both innate and adaptive immunity to generate potent antitumor responses that require perforin but are independent of IFN-gamma. J Immunol. 2003 Jul 15; 171(2):608-15.