T-Lymphocytes, Helper-Inducer

"T-Lymphocytes, Helper-Inducer" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Subpopulation of CD4+ lymphocytes that cooperate with other lymphocytes (either T or B) to initiate a variety of immune functions. For example, helper-inducer T-cells cooperate with B-cells to produce antibodies to thymus-dependent antigens and with other subpopulations of T-cells to initiate a variety of cell-mediated immune functions.

Descriptor ID	D006377
MeSH Number(s)	A11.118.637.555.567.550.500.400 A11.118.637.555.567.569.200.400 A11.118.637.555.567.569.500.400 A15.145.229.637.555.567.550.500.400 A15.145.229.637.555.567.569.200.400 A15.145.229.637.555.567.569.500.400 A15.382.490.555.567.550.500.400 A15.382.490.555.567.569.200.400 A15.382.490.555.567.569.500.400
Concept/Terms	T-Lymphocytes, Helper-Inducer T-Lymphocytes, Helper-Inducer T Lymphocytes, Helper Inducer T-Lymphocytes, Inducer Inducer T-Lymphocyte Inducer T-Lymphocytes T Lymphocytes, Inducer T-Lymphocyte, Inducer T-Cells, Helper-Inducer Helper-Inducer T-Cell Helper-Inducer T-Cells T Cells, Helper Inducer T-Cell, Helper-Inducer Helper T-Cells Helper T Cells Helper T-Cell T-Cell, Helper T-Cells, Helper Helper-Inducer T-Lymphocytes Helper Inducer T Lymphocytes Helper-Inducer T-Lymphocyte T-Lymphocyte, Helper-Inducer Inducer Cells Inducer Cell T-Lymphocytes, Helper Helper T-Lymphocyte Helper T-Lymphocytes T Lymphocytes, Helper T-Lymphocyte, Helper Helper Cells Helper Cell

Below are MeSH descriptors whose meaning is more general than "T-Lymphocytes, Helper-Inducer".

Anatomy [A]
Cells [A11]
Blood Cells [A11.118]
Leukocytes [A11.118.637]
Leukocytes, Mononuclear [A11.118.637.555]
Lymphocytes [A11.118.637.555.567]
Lymphocyte Subsets [A11.118.637.555.567.550]
T-Lymphocyte Subsets [A11.118.637.555.567.550.500]
T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.550.500.400]
T-Lymphocytes [A11.118.637.555.567.569]
CD4-Positive T-Lymphocytes [A11.118.637.555.567.569.200]
T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.569.200.400]
T-Lymphocyte Subsets [A11.118.637.555.567.569.500]
T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.569.500.400]
Hemic and Immune Systems [A15]
Blood [A15.145]
Blood Cells [A15.145.229]
Leukocytes [A15.145.229.637]
Leukocytes, Mononuclear [A15.145.229.637.555]
Lymphocytes [A15.145.229.637.555.567]
Lymphocyte Subsets [A15.145.229.637.555.567.550]
T-Lymphocyte Subsets [A15.145.229.637.555.567.550.500]
T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.550.500.400]
T-Lymphocytes [A15.145.229.637.555.567.569]
CD4-Positive T-Lymphocytes [A15.145.229.637.555.567.569.200]
T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.569.200.400]
T-Lymphocyte Subsets [A15.145.229.637.555.567.569.500]
T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.569.500.400]
Immune System [A15.382]
Leukocytes [A15.382.490]
Leukocytes, Mononuclear [A15.382.490.555]
Lymphocytes [A15.382.490.555.567]
Lymphocyte Subsets [A15.382.490.555.567.550]
T-Lymphocyte Subsets [A15.382.490.555.567.550.500]
T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.550.500.400]
T-Lymphocytes [A15.382.490.555.567.569]
CD4-Positive T-Lymphocytes [A15.382.490.555.567.569.200]
T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.569.200.400]
T-Lymphocyte Subsets [A15.382.490.555.567.569.500]
T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.569.500.400]

Below are MeSH descriptors whose meaning is related to "T-Lymphocytes, Helper-Inducer".

Below are MeSH descriptors whose meaning is more specific than "T-Lymphocytes, Helper-Inducer".

T-Lymphocytes, Helper-Inducer
Th1 Cells
Th17 Cells
Th2 Cells

publications

Timeline | Most Recent

This graph shows the total number of publications written about "T-Lymphocytes, Helper-Inducer" by people in this website by year, and whether "T-Lymphocytes, Helper-Inducer" was a major or minor topic of these publications.

Bar chart showing 65 publications over 29 distinct years, with a maximum of 6 publications in 2009 and 2010

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	0	1
1997	0	1	1
1998	2	0	2
1999	2	2	4
2000	0	1	1
2001	2	1	3
2002	0	2	2
2003	1	0	1
2004	1	1	2
2005	2	0	2
2006	1	1	2
2007	1	1	2
2008	3	1	4
2009	6	0	6
2010	4	2	6
2011	1	0	1
2012	0	1	1
2013	2	0	2
2014	0	1	1
2015	1	0	1
2016	1	0	1
2017	3	2	5
2018	3	0	3
2019	1	0	1
2020	4	0	4
2021	1	1	2
2022	0	2	2
2023	0	1	1
2024	0	1	1

Below are the most recent publications written about "T-Lymphocytes, Helper-Inducer" by people in Profiles.

Chen JS, Lee D, Gowthaman U. T follicular helper cells in food allergy. Curr Opin Immunol. 2024 Dec; 91:102461.

View in: PubMed
Abboud G, Choi SC, Zhang X, Park YP, Kanda N, Zeumer-Spataro L, Terrell M, Teng X, N?ndel K, Shlomchik MJ, Morel L. Glucose Requirement of Antigen-Specific Autoreactive B Cells and CD4+ T Cells. J Immunol. 2023 02 15; 210(4):377-388.

View in: PubMed
Lee D, Krishnaswamy JK, Gowthaman U. Common and distinct roles for TH2 and TFH cells in shaping the spectrum of allergic diseases. J Allergy Clin Immunol. 2022 Nov; 150(5):1050-1052.

View in: PubMed
Devarajan P, Vong AM, Castonguay CH, Kugler-Umana O, Bautista BL, Jones MC, Kelly KA, Xia J, Swain SL. Strong influenza-induced TFH generation requires CD4 effectors to recognize antigen locally and receive signals from continuing infection. Proc Natl Acad Sci U S A. 2022 02 22; 119(8).

View in: PubMed
Gowthaman U, Sikder S, Lee D, Fisher C. T follicular helper cells in IgE-mediated pathologies. Curr Opin Immunol. 2022 02; 74:133-139.

View in: PubMed
Lu YJ, Barreira-Silva P, Boyce S, Powers J, Cavallo K, Behar SM. CD4 T?cell help prevents CD8 T?cell exhaustion and promotes control of Mycobacterium tuberculosis infection. Cell Rep. 2021 09 14; 36(11):109696.

View in: PubMed
Kaneko N, Kuo HH, Boucau J, Farmer JR, Allard-Chamard H, Mahajan VS, Piechocka-Trocha A, Lefteri K, Osborn M, Bals J, Bartsch YC, Bonheur N, Caradonna TM, Chevalier J, Chowdhury F, Diefenbach TJ, Einkauf K, Fallon J, Feldman J, Finn KK, Garcia-Broncano P, Hartana CA, Hauser BM, Jiang C, Kaplonek P, Karpell M, Koscher EC, Lian X, Liu H, Liu J, Ly NL, Michell AR, Rassadkina Y, Seiger K, Sessa L, Shin S, Singh N, Sun W, Sun X, Ticheli HJ, Waring MT, Zhu AL, Alter G, Li JZ, Lingwood D, Schmidt AG, Lichterfeld M, Walker BD, Yu XG, Padera RF, Pillai S. Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19. Cell. 2020 10 01; 183(1):143-157.e13.

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Zhang B, Liu E, Gertie JA, Joseph J, Xu L, Pinker EY, Waizman DA, Catanzaro J, Hamza KH, Lahl K, Gowthaman U, Eisenbarth SC. Divergent T follicular helper cell requirement for IgA and IgE production to peanut during allergic sensitization. Sci Immunol. 2020 05 08; 5(47).

View in: PubMed
Chodisetti SB, Fike AJ, Domeier PP, Schell SL, Mockus TE, Choi NM, Corradetti C, Hou B, Atkins HM, Caricchio R, Decker T, Lukacher AE, Olsen N, Rahman ZSM. Serine Phosphorylation of the STAT1 Transactivation Domain Promotes Autoreactive B Cell and Systemic Autoimmunity Development. J Immunol. 2020 05 15; 204(10):2641-2650.

View in: PubMed
Gowthaman U, Chen JS, Eisenbarth SC. Regulation of IgE by T follicular helper cells. J Leukoc Biol. 2020 03; 107(3):409-418.

View in: PubMed

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