Intraepithelial Lymphocytes
"Intraepithelial Lymphocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
T Lymphocytes with limited diversity of receptors (e.g., ALPHA E INTEGRINS) in the epidermis of the skin and the mucosal linings. They recognize common microbes via T-CELL RECEPTORS and PATHOGEN-ASSOCIATED MOLECULAR PATTERN MOLECULES and function as effector cells for INNATE IMMUNITY. Activation of intraepithelial lymphocytes is a marker for various gastrointestinal diseases (e.g., CELIAC DISEASE; HAIRY CELL LEUKEMIA; and ENTEROPATHY-ASSOCIATED T-CELL LYMPHOMA).
| Descriptor ID |
D000075942
|
| MeSH Number(s) |
A11.118.637.555.567.550.500.050 A11.118.637.555.567.569.500.050 A15.145.229.637.555.567.550.500.050 A15.145.229.637.555.567.569.500.050 A15.382.490.555.567.550.500.050 A15.382.490.555.567.569.500.050
|
| Concept/Terms |
Intraepithelial Lymphocytes- Intraepithelial Lymphocytes
- Intraepithelial Lymphocyte
- Lymphocyte, Intraepithelial
- Lymphocytes, Intraepithelial
- Gamma Delta T Lymphocytes
- Intraepithelial T Cells
- Intraepithelial T Cell
- T Cell, Intraepithelial
- T Cells, Intraepithelial
- Mucosal T Lymphocytes
- Mucosal T Lymphocyte
- T Lymphocyte, Mucosal
- T Lymphocytes, Mucosal
- Mucosal T Cells
- Mucosal T Cell
- T Cell, Mucosal
- T Cells, Mucosal
- Gamma Delta T Cells
- Intraepithelial T Lymphocytes
- Intraepithelial T Lymphocyte
- T Lymphocyte, Intraepithelial
- T Lymphocytes, Intraepithelial
|
Below are MeSH descriptors whose meaning is more general than "Intraepithelial Lymphocytes".
Below are MeSH descriptors whose meaning is more specific than "Intraepithelial Lymphocytes".
This graph shows the total number of publications written about "Intraepithelial Lymphocytes" by people in this website by year, and whether "Intraepithelial Lymphocytes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2019 | 0 | 1 | 1 |
| 2021 | 2 | 0 | 2 |
| 2022 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Intraepithelial Lymphocytes" by people in Profiles.
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Harmon C, Zaborowski A, Moore H, St Louis P, Slattery K, Duquette D, Scanlan J, Kane H, Kunkemoeller B, McIntyre CL, Scannail AN, Moran B, Anderson AC, Winter D, Brennan D, Brehm MA, Lynch L. ?d T cell dichotomy with opposing cytotoxic and wound healing functions in human solid tumors. Nat Cancer. 2023 08; 4(8):1122-1137.
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Lei X, Ketelut-Carneiro N, Shmuel-Galia L, Xu W, Wilson R, Vierbuchen T, Chen Y, Reboldi A, Kang J, Edelblum KL, Ward D, Fitzgerald KA. Epithelial HNF4A shapes the intraepithelial lymphocyte compartment via direct regulation of immune signaling molecules. J Exp Med. 2022 08 01; 219(8).
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Lechner K, Mott S, Al-Saifi R, Knipfer L, Wirtz S, Atreya R, Vieth M, Rath T, Fraass T, Winter Z, August A, Luban J, Zimmermann VS, Weigmann B, Neurath MF. Targeting of the Tec Kinase ITK Drives Resolution of T Cell-Mediated Colitis and Emerges as Potential Therapeutic Option in Ulcerative Colitis. Gastroenterology. 2021 10; 161(4):1270-1287.e19.
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Junqueira C, Polidoro RB, Castro G, Absalon S, Liang Z, Sen Santara S, Crespo ?, Pereira DB, Gazzinelli RT, Dvorin JD, Lieberman J. ?d T cells suppress Plasmodium falciparum blood-stage infection by direct killing and phagocytosis. Nat Immunol. 2021 03; 22(3):347-357.
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Negroni MP, Cho OH, Stern LJ. Recognition of Listeria Infection by Germline Elements of the V?1.1 Vd6.3 TCR. Immunohorizons. 2019 07 18; 3(7):341-351.