Hepatitis, Alcoholic

"Hepatitis, Alcoholic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

INFLAMMATION of the LIVER due to ALCOHOL ABUSE. It is characterized by NECROSIS of HEPATOCYTES, infiltration by NEUTROPHILS, and deposit of MALLORY BODIES. Depending on its severity, the inflammatory lesion may be reversible or progress to LIVER CIRRHOSIS.

Descriptor ID	D006519
MeSH Number(s)	C06.552.380.290 C06.552.645.490 C25.775.100.087.645.490
Concept/Terms	Hepatitis, Alcoholic Hepatitis, Alcoholic Alcoholic Hepatitis Chronic Alcoholic Hepatitis Chronic Alcoholic Hepatitis Alcoholic Hepatitis, Chronic Chronic Alcoholic Hepatitides Hepatitis, Alcoholic, Chronic

Below are MeSH descriptors whose meaning is more general than "Hepatitis, Alcoholic".

Diseases [C]
Digestive System Diseases [C06]
Liver Diseases [C06.552]
Hepatitis [C06.552.380]
Hepatitis, Alcoholic [C06.552.380.290]
Liver Diseases, Alcoholic [C06.552.645]
Hepatitis, Alcoholic [C06.552.645.490]
Chemically-Induced Disorders [C25]
Substance-Related Disorders [C25.775]
Alcohol-Related Disorders [C25.775.100]
Alcohol-Induced Disorders [C25.775.100.087]
Liver Diseases, Alcoholic [C25.775.100.087.645]
Hepatitis, Alcoholic [C25.775.100.087.645.490]

Below are MeSH descriptors whose meaning is related to "Hepatitis, Alcoholic".

Below are MeSH descriptors whose meaning is more specific than "Hepatitis, Alcoholic".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Hepatitis, Alcoholic" by people in this website by year, and whether "Hepatitis, Alcoholic" was a major or minor topic of these publications.

Bar chart showing 40 publications over 12 distinct years, with a maximum of 5 publications in 2015 and 2019 and 2020 and 2023

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2005	0	1	1
2009	1	0	1
2015	4	1	5
2016	4	0	4
2017	3	0	3
2018	2	0	2
2019	3	2	5
2020	4	1	5
2021	1	0	1
2022	4	0	4
2023	4	1	5
2024	3	1	4

Below are the most recent publications written about "Hepatitis, Alcoholic" by people in Profiles.

Mandrekar P, Mandal A. Pathogenesis of Alcohol-Associated Liver Disease. Clin Liver Dis. 2024 Nov; 28(4):647-661.

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Babuta M, Morel C, de Carvalho Ribeiro M, Datta AA, Calenda C, Copeland C, Nasser I, Szabo G. A novel experimental model of MetALD in male mice recapitulates key features of severe alcohol-associated hepatitis. Hepatol Commun. 2024 07 01; 8(7).

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Taiwo M, Huang E, Pathak V, Bellar A, Welch N, Dasarathy J, Streem D, McClain CJ, Mitchell MC, Barton BA, Szabo G, Dasarathy S, Schaefer EA, Luther J, Day LZ, Ouyang X, Suyavaran A, Mehal WZ, Jacobs JM, Goodman RP, Rotroff DM, Nagy LE. Proteomics identifies complement protein signatures in patients with alcohol-associated hepatitis. JCI Insight. 2024 04 04; 9(9).

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Gawrieh S, Dasarathy S, Tu W, Kamath PS, Chalasani NP, McClain CJ, Bataller R, Szabo G, Tang Q, Radaeva S, Barton B, Nagy LE, Shah VH, Sanyal AJ, Mitchell MC. Randomized trial of anakinra plus zinc vs. prednisone for severe alcohol-associated hepatitis. J Hepatol. 2024 May; 80(5):684-693.

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Tornai D, Mitchell M, McClain CJ, Dasarathy S, McCullough A, Radaeva S, Kroll-Desrosiers A, Lee J, Barton B, Szabo G. A novel score of IL-13 and age predicts 90-day mortality in severe alcohol-associated hepatitis: A multicenter plasma biomarker analysis. Hepatol Commun. 2023 12 01; 7(12).

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Mrdjen M, Huang E, Pathak V, Bellar A, Welch N, Dasarathy J, Streem D, McClain CJ, Mitchell M, Radaeva S, Barton B, Szabo G, Dasarathy S, Wang Z, Hazen SL, Brown JM, Nagy LE. Dysregulated meta-organismal metabolism of aromatic amino acids in alcohol-associated liver disease. Hepatol Commun. 2023 11 01; 7(11).

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Vatsalya V, Feng W, Kong M, Hu H, Szabo G, McCullough A, Dasarathy S, Nagy LE, Radaeva S, Barton B, Mitchell M, McClain CJ. The Beneficial Effects of Lactobacillus GG Therapy on Liver and Drinking Assessments in Patients with Moderate Alcohol-Associated Hepatitis. Am J Gastroenterol. 2023 08 01; 118(8):1457-1460.

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Hassanein T, McClain CJ, Vatsalya V, Stein LL, Flamm SL, Martin P, Cave MC, Mitchell M, Barton B, Nagy L, Szabo G, McCullough A, Dasarathy S, Shah J, Blevins C, Scott D, Krebs W, Brown JE, Lin W. Safety, Pharmacokinetics, and Efficacy Signals of Larsucosterol (DUR-928) in Alcohol-Associated Hepatitis. Am J Gastroenterol. 2024 01 01; 119(1):107-115.

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de Carvalho Ribeiro M, Iracheta-Vellve A, Babuta M, Calenda CD, Copeland C, Zhuang Y, Lowe PP, Hawryluk D, Catalano D, Cho Y, Barton B, Dasarathy S, McClain C, McCullough AJ, Mitchell MC, Nagy LE, Radaeva S, Lien E, Golenbock DT, Szabo G. Alcohol-induced extracellular ASC specks perpetuate liver inflammation and damage in alcohol-associated hepatitis even after alcohol cessation. Hepatology. 2023 07 01; 78(1):225-242.

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Cho Y, Bukong TN, Tornai D, Babuta M, Vlachos IS, Kanata E, Catalano D, Szabo G. Neutrophil extracellular traps contribute to liver damage and increase defective low-density neutrophils in alcohol-associated hepatitis. J Hepatol. 2023 01; 78(1):28-44.

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