Vaccines, Attenuated

"Vaccines, Attenuated" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Live vaccines prepared from microorganisms which have undergone physical adaptation (e.g., by radiation or temperature conditioning) or serial passage in laboratory animal hosts or infected tissue/cell cultures, in order to produce avirulent mutant strains capable of inducing protective immunity.

Descriptor ID	D014613
MeSH Number(s)	D20.215.894.811
Concept/Terms	Vaccines, Attenuated Vaccines, Attenuated Attenuated Vaccines Vaccines, Live, Attenuated

Below are MeSH descriptors whose meaning is more general than "Vaccines, Attenuated".

Chemicals and Drugs [D]
Complex Mixtures [D20]
Biological Products [D20.215]
Vaccines [D20.215.894]
Vaccines, Attenuated [D20.215.894.811]

Below are MeSH descriptors whose meaning is related to "Vaccines, Attenuated".

Below are MeSH descriptors whose meaning is more specific than "Vaccines, Attenuated".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Vaccines, Attenuated" by people in this website by year, and whether "Vaccines, Attenuated" was a major or minor topic of these publications.

Bar chart showing 26 publications over 18 distinct years, with a maximum of 4 publications in 2002

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1993	1	0	1
2002	0	4	4
2004	0	2	2
2005	0	1	1
2006	0	1	1
2007	2	1	3
2008	0	1	1
2009	0	2	2
2010	0	1	1
2011	0	1	1
2012	0	1	1
2013	0	1	1
2014	0	1	1
2016	0	1	1
2017	0	1	1
2018	1	1	2
2019	0	1	1
2022	0	1	1

Below are the most recent publications written about "Vaccines, Attenuated" by people in Profiles.

Devarajan P, Vong AM, Castonguay CH, Kugler-Umana O, Bautista BL, Jones MC, Kelly KA, Xia J, Swain SL. Strong influenza-induced TFH generation requires CD4 effectors to recognize antigen locally and receive signals from continuing infection. Proc Natl Acad Sci U S A. 2022 02 22; 119(8).

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Beernink PT, Ispasanie E, Lewis LA, Ram S, Moe GR, Granoff DM. A Meningococcal Native Outer Membrane Vesicle Vaccine With Attenuated Endotoxin and Overexpressed Factor H Binding Protein Elicits Gonococcal Bactericidal Antibodies. J Infect Dis. 2019 03 15; 219(7):1130-1137.

View in: PubMed
Whelan AO, Flick-Smith HC, Homan J, Shen ZT, Carpenter Z, Khoshkenar P, Abraham A, Walker NJ, Levitz SM, Ostroff GR, Oyston PCF. Protection induced by a Francisella tularensis subunit vaccine delivered by glucan particles. PLoS One. 2018; 13(10):e0200213.

View in: PubMed
K?ster S, Klevorn T, Papavinasasundaram K, Sassetti CM, Portal-Celhay C, Philips JA. Consequence of enhanced LC3-trafficking for a live, attenuated M. tuberculosis vaccine. Vaccine. 2018 02 08; 36(7):939-944.

View in: PubMed
Grifoni A, Pham J, Sidney J, O'Rourke PH, Paul S, Peters B, Martini SR, de Silva AD, Ricciardi MJ, Magnani DM, Silveira CGT, Maestri A, Costa PR, de-Oliveira-Pinto LM, de Azeredo EL, Damasco PV, Phillips E, Mallal S, de Silva AM, Collins M, Durbin A, Diehl SA, Cerpas C, Balmaseda A, Kuan G, Coloma J, Harris E, Crowe JE, Stone M, Norris PJ, Busch M, Vivanco-Cid H, Cox J, Graham BS, Ledgerwood JE, Turtle L, Solomon T, Kallas EG, Watkins DI, Weiskopf D, Sette A. Prior Dengue Virus Exposure Shapes T Cell Immunity to Zika Virus in Humans. J Virol. 2017 12 15; 91(24).

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Rothman AL, Ennis FA. Dengue Vaccine: The Need, the Challenges, and Progress. J Infect Dis. 2016 09 15; 214(6):825-7.

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Santos E, Levitz SM. Fungal vaccines and immunotherapeutics. Cold Spring Harb Perspect Med. 2014 Nov 03; 4(11):a019711.

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Gil A, Shen S, Coley S, Gibson L, Diamond DJ, Wang S, Lu S. DNA vaccine prime followed by boost with live attenuated virus significantly improves antigen-specific T cell responses against human cytomegalovirus. Hum Vaccin Immunother. 2013 Oct; 9(10):2120-32.

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Alpert MD, Harvey JD, Lauer WA, Reeves RK, Piatak M, Carville A, Mansfield KG, Lifson JD, Li W, Desrosiers RC, Johnson RP, Evans DT. ADCC develops over time during persistent infection with live-attenuated SIV and is associated with complete protection against SIV(mac)251 challenge. PLoS Pathog. 2012; 8(8):e1002890.

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Smith HL, Monath TP, Pazoles P, Rothman AL, Casey DM, Terajima M, Ennis FA, Guirakhoo F, Green S. Development of antigen-specific memory CD8+ T cells following live-attenuated chimeric West Nile virus vaccination. J Infect Dis. 2011 Feb 15; 203(4):513-22.

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