Group IV Phospholipases A2
"Group IV Phospholipases A2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytosolic phospholipase A2 group that plays an important role in the release of free ARACHIDONIC ACID, which in turn is metabolized to PROSTAGLANDINS by the CYCLOOXYGENASE pathway and to LEUKOTRIENES by the 5-LIPOXYGENASE pathway.
| Descriptor ID |
D054513
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| MeSH Number(s) |
D08.811.277.352.100.680.750.937.625.249
|
| Concept/Terms |
Group IV Phospholipases A2- Group IV Phospholipases A2
- PLA2-IV
- Phospholipases A2, Group IV
- PLA(2)-IV
- Group IV Cytosolic Phospholipase A2
- Phospholipase A2 IV
Group IVB Phospholipase A2- Group IVB Phospholipase A2
- Phospholipase A2-beta
- Phospholipase A2 beta
- Phospholipase A2, Group IVB
- Cytosolic Phospholipase A2 beta
- Group IVB Phospholipases A2
Group IVC Phospholipase A2- Group IVC Phospholipase A2
- Phospholipase A2, Group IVC
- Cytosolic Phospholipase A2 gamma
- cPLA2-gamma
- cPLA2 gamma
- Group IVC Phospholipases A2
- Phospholipase A2-gamma
- Phospholipase A2 gamma
Group IVE Phospholipase A2- Group IVE Phospholipase A2
- Group IVE Phospholipases A2
- Phospholipase A2, Group IVE
- Cytosolic Phospholipase A2 epsilon
Group IVA Phospholipase A2- Group IVA Phospholipase A2
- Cytosolic Phospholipase A2 alpha
- Phospholipase A2-alpha
- Phospholipase A2 alpha
- Phospholipase A(2)alpha
- Phospholipase A2 Group IVA
- cPLA2-alpha
- cPLA2 alpha
- Group IVA Phospholipases A2
Group IVD Phospholipase A2- Group IVD Phospholipase A2
- Group IVD Phospholipases A2
- Phospholipase A2, Group IVD
- Cytosolic Phospholipase A2 delta
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Below are MeSH descriptors whose meaning is more general than "Group IV Phospholipases A2".
Below are MeSH descriptors whose meaning is more specific than "Group IV Phospholipases A2".
This graph shows the total number of publications written about "Group IV Phospholipases A2" by people in this website by year, and whether "Group IV Phospholipases A2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Group IV Phospholipases A2" by people in Profiles.
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Liu L, Bonventre JV, Rittenhouse AR. cPLA2a-/- sympathetic neurons exhibit increased membrane excitability and loss of N-Type Ca2+ current inhibition by M1 muscarinic receptor signaling. PLoS One. 2018; 13(12):e0201322.
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Bhowmick R, Clark S, Bonventre JV, Leong JM, McCormick BA. Cytosolic Phospholipase A2a Promotes Pulmonary Inflammation and Systemic Disease during Streptococcus pneumoniae Infection. Infect Immun. 2017 11; 85(11).
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Bickford JS, Newsom KJ, Herlihy JD, Mueller C, Keeler B, Qiu X, Walters JN, Su N, Wallet SM, Flotte TR, Nick HS. Induction of group IVC phospholipase A2 in allergic asthma: transcriptional regulation by TNFa in bronchoepithelial cells. Biochem J. 2012 Feb 15; 442(1):127-37.
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Hurley BP, Pirzai W, Mumy KL, Gronert K, McCormick BA. Selective eicosanoid-generating capacity of cytoplasmic phospholipase A2 in Pseudomonas aeruginosa-infected epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2011 Feb; 300(2):L286-94.
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Hurley BP, Williams NL, McCormick BA. Involvement of phospholipase A2 in Pseudomonas aeruginosa-mediated PMN transepithelial migration. Am J Physiol Lung Cell Mol Physiol. 2006 Apr; 290(4):L703-L709.