Mink Cell Focus-Inducing Viruses
"Mink Cell Focus-Inducing Viruses" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Strains of MURINE LEUKEMIA VIRUS discovered in 1976 by Hartley, Wolford, Old, and Rowe and so named because the viruses originally isolated had the capacity to transform cell foci in mink cell cultures. MCF viruses are generated by recombination with ecotropic murine leukemia viruses including AKR, Friend, Moloney, and Rauscher, causing ERYTHROLEUKEMIA and severe anemia in mice.
| Descriptor ID |
D008908
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| MeSH Number(s) |
B04.613.807.375.525.580 B04.820.650.375.525.580
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| Concept/Terms |
Mink Cell Focus-Inducing Viruses- Mink Cell Focus-Inducing Viruses
- Mink Cell Focus Inducing Viruses
- Mink cell focus-inducing virus
- Mink cell focus inducing virus
- MCF Viruses
- MCF Virus
- Virus, MCF
- Viruses, MCF
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Below are MeSH descriptors whose meaning is more general than "Mink Cell Focus-Inducing Viruses".
Below are MeSH descriptors whose meaning is more specific than "Mink Cell Focus-Inducing Viruses".
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Below are the most recent publications written about "Mink Cell Focus-Inducing Viruses" by people in Profiles.
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DiFronzo NL, Frieder M, Loiler SA, Pham QN, Holland CA. Duplication of U3 sequences in the long terminal repeat of mink cell focus-inducing viruses generates redundancies of transcription factor binding sites important for the induction of thymomas. J Virol. 2003 Mar; 77(5):3326-33.
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Loiler SA, DiFronzo NL, Holland CA. Gene transfer to human cells using retrovirus vectors produced by a new polytropic packaging cell line. J Virol. 1997 Jun; 71(6):4825-8.
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Mojcik CF, Gourley MF, Klinman DM, Krieg AM, Gmelig-Meyling F, Steinberg AD. Administration of a phosphorothioate oligonucleotide antisense to murine endogenous retroviral MCF env causes immune effects in vivo in a sequence-specific manner. Clin Immunol Immunopathol. 1993 May; 67(2):130-6.
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Gourley MF, Krieg AM, Steinberg AD. Preferential nuclear compartmentalization of endogenous mink cell focus-forming-related retroviral transcripts. J Exp Med. 1990 May 01; 171(5):1443-52.
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Krieg AM, Gause WC, Gourley MF, Steinberg AD. A role for endogenous retroviral sequences in the regulation of lymphocyte activation. J Immunol. 1989 Oct 15; 143(8):2448-51.
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Krieg AM, Khan AS, Steinberg AD. Expression of an endogenous retroviral transcript is associated with murine lupus. Arthritis Rheum. 1989 Mar; 32(3):322-9.
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Krieg AM, Khan AS, Steinberg AD. Multiple endogenous xenotropic and mink cell focus-forming murine leukemia virus-related transcripts are induced by polyclonal immune activators. J Virol. 1988 Oct; 62(10):3545-50.