"Calcimycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An ionophorous, polyether antibiotic from Streptomyces chartreusensis. It binds and transports CALCIUM and other divalent cations across membranes and uncouples oxidative phosphorylation while inhibiting ATPase of rat liver mitochondria. The substance is used mostly as a biochemical tool to study the role of divalent cations in various biological systems.
| Descriptor ID |
D000001
|
| MeSH Number(s) |
D03.633.100.221.173
|
| Concept/Terms |
A-23187- A-23187
- A 23187
- A23187
- Antibiotic A23187
- A23187, Antibiotic
|
Below are MeSH descriptors whose meaning is more general than "Calcimycin".
Below are MeSH descriptors whose meaning is more specific than "Calcimycin".
This graph shows the total number of publications written about "Calcimycin" by people in this website by year, and whether "Calcimycin" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1999 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2016 | 0 | 2 | 2 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Calcimycin" by people in Profiles.
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Osycka-Salut CE, Waremkraut M, Garaguso R, Piga E, Mart?nez-Le?n E, Mar?n-Briggiler CI, Gervasi MG, Navarro M, Visconti PE, Buffone MG, Mutto AA, Krapf D. Treatment of cryopreserved bovine sperm with calcium ionophore A23187 increases in vitro embryo production. Theriogenology. 2024 Nov; 229:1-7.
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S?nchez-C?rdenas C, Montoya F, Navarrete FA, Hern?ndez-Cruz A, Corkidi G, Visconti PE, Darszon A. Intracellular Ca2+ threshold reversibly switches flagellar beat off and on. Biol Reprod. 2018 11 01; 99(5):1010-1021.
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Kenny EF, Herzig A, Kr?ger R, Muth A, Mondal S, Thompson PR, Brinkmann V, Bernuth HV, Zychlinsky A. Diverse stimuli engage different neutrophil extracellular trap pathways. Elife. 2017 06 02; 6.
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Pelletier MG, Szymczak K, Barbeau AM, Prata GN, O'Fallon KS, Gaines P. Characterization of neutrophils and macrophages from ex vivo-cultured murine bone marrow for morphologic maturation and functional responses by imaging flow cytometry. Methods. 2017 01 01; 112:124-146.
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Navarrete FA, Alvau A, Lee HC, Levin LR, Buck J, Leon PM, Santi CM, Krapf D, Mager J, Fissore RA, Salicioni AM, Darszon A, Visconti PE. Transient exposure to calcium ionophore enables in vitro fertilization in sterile mouse models. Sci Rep. 2016 09 15; 6:33589.
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Li C, Reif MM, Craige SM, Kant S, Keaney JF. Endothelial AMPK activation induces mitochondrial biogenesis and stress adaptation via eNOS-dependent mTORC1 signaling. Nitric Oxide. 2016 05 01; 55-56:45-53.
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Tateno H, Krapf D, Hino T, S?nchez-C?rdenas C, Darszon A, Yanagimachi R, Visconti PE. Ca2+ ionophore A23187 can make mouse spermatozoa capable of fertilizing in vitro without activation of cAMP-dependent phosphorylation pathways. Proc Natl Acad Sci U S A. 2013 Nov 12; 110(46):18543-8.
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Leung R, Gwozdz AM, Wang H, Bang KW, Packham MA, Freedman J, Rand ML. Persistence of procoagulant surface expression on activated human platelets: involvement of apoptosis and aminophospholipid translocase activity. J Thromb Haemost. 2007 Mar; 5(3):560-70.
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Uston PI, Urban JF, Ashraf M, Lee CM, Ampy FR. L3L4ES antigen and secretagogues induce histamine release from porcine peripheral blood basophils after Ascaris suum infection. Parasitol Res. 2007 Feb; 100(3):603-11.
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Shanmugham LN, Petrarca C, Castellani ML, Frydas S, Vecchiet J, Conti P, Tete S. Rantes potentiates human macrophage aggregation and activation responses to calcium ionophore (A23187) and activates arachidonic acid pathways. J Biol Regul Homeost Agents. 2006 Jan-Jun; 20(1-2):15-23.