"Phenobarbital" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
Descriptor ID |
D010634
|
MeSH Number(s) |
D03.383.742.698.253.650
|
Concept/Terms |
Phenobarbital- Phenobarbital
- Phenylbarbital
- Phenylethylbarbituric Acid
- Acid, Phenylethylbarbituric
- Phenemal
- Phenobarbitone
Phenobarbital Sodium- Phenobarbital Sodium
- Sodium, Phenobarbital
- Phenobarbital, Monosodium Salt
- Monosodium Salt Phenobarbital
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Below are MeSH descriptors whose meaning is more general than "Phenobarbital".
Below are MeSH descriptors whose meaning is more specific than "Phenobarbital".
This graph shows the total number of publications written about "Phenobarbital" by people in this website by year, and whether "Phenobarbital" was a major or minor topic of these publications.
To see the data from this visualization as text,
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Year | Major Topic | Minor Topic | Total |
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2005 | 0 | 1 | 1 |
2013 | 1 | 1 | 2 |
2014 | 1 | 0 | 1 |
2020 | 1 | 0 | 1 |
2021 | 0 | 1 | 1 |
2022 | 0 | 1 | 1 |
2023 | 0 | 2 | 2 |
2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Phenobarbital" by people in Profiles.
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Long B, Keim SM, Gottlieb M, Rathlev N. Is Phenobarbital an Effective Treatment for Alcohol Withdrawal Syndrome? J Emerg Med. 2024 Nov; 67(5):e494-e503.
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Holmes LB, Hunt AT, Will LA, Dhillon R, Deutsch C, Adams J. Facial dysmorphology in children exposed in pregnancy to anticonvulsant medications correlates with deficits in IQ. Am J Med Genet A. 2024 04; 194(4):e63511.
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Kip LM, Forni A, Dorfman JD, Li I. Evaluation of phenobarbital for prevention of alcohol withdrawal in trauma patients. J Trauma Acute Care Surg. 2023 10 01; 95(4):573-576.
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Bosch NA, Law AC, Walkey AJ. Phenobarbital for Severe Alcohol Withdrawal Syndrome: A Multicenter Retrospective Cohort Study. Am J Respir Crit Care Med. 2022 11 01; 206(9):1171-1174.
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Bosch NA, Crable EL, Ackerbauer KA, Clark K, Drainoni ML, Grim V, Ieong MH, Walkey AJ, Murphy J. Implementation of a Phenobarbital-based Pathway for Severe Alcohol Withdrawal: A Mixed-Method Study. Ann Am Thorac Soc. 2021 10; 18(10):1708-1716.
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Alix V, James M, Jackson AH, Visintainer PF, Singh R. Efficacy of Fosphenytoin as First-Line Antiseizure Medication for Neonatal Seizures Compared to Phenobarbital. J Child Neurol. 2021 01; 36(1):30-37.
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Singh R, Visintainer PF. Adjunctive therapy for neonatal abstinence syndrome: why not personalize it for each infant based on their in-utero exposure? J Perinatol. 2014 Jul; 34(7):575-6.
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Surran B, Visintainer P, Chamberlain S, Kopcza K, Shah B, Singh R. Efficacy of clonidine versus phenobarbital in reducing neonatal morphine sulfate therapy days for neonatal abstinence syndrome. A prospective randomized clinical trial. J Perinatol. 2013 Dec; 33(12):954-9.
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Burns JM, Marino A, Manno M, Rhyee S, Boyer EW. Status epilepticus in a child secondary to ingestion of skin-lightening cream. Pediatr Emerg Care. 2013 May; 29(5):662-4.
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Holmes LB, Coull BA, Dorfman J, Rosenberger PB. The correlation of deficits in IQ with midface and digit hypoplasia in children exposed in utero to anticonvulsant drugs. J Pediatr. 2005 Jan; 146(1):118-22.