Sepsis

"Sepsis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.

Descriptor ID	D018805
MeSH Number(s)	C01.539.757 C23.550.470.790.500
Concept/Terms	Sepsis Sepsis Severe Sepsis Severe Sepsis Sepsis, Severe Pyemia Pyemia Pyemias Pyohemia Pyohemias Pyaemia Pyaemias Septicemia Septicemia Septicemias Poisoning, Blood Blood Poisoning Blood Poisonings Poisonings, Blood

Below are MeSH descriptors whose meaning is more general than "Sepsis".

Diseases [C]
Bacterial Infections and Mycoses [C01]
Infection [C01.539]
Sepsis [C01.539.757]
Pathological Conditions, Signs and Symptoms [C23]
Pathologic Processes [C23.550]
Inflammation [C23.550.470]
Systemic Inflammatory Response Syndrome [C23.550.470.790]
Sepsis [C23.550.470.790.500]

Below are MeSH descriptors whose meaning is more specific than "Sepsis".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Sepsis" by people in this website by year, and whether "Sepsis" was a major or minor topic of these publications.

Bar chart showing 199 publications over 29 distinct years, with a maximum of 16 publications in 2014 and 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
1997	0	1	1
1998	1	0	1
2001	2	3	5
2002	3	0	3
2003	3	0	3
2004	0	1	1
2005	1	0	1
2006	2	1	3
2007	3	1	4
2008	4	0	4
2009	1	1	2
2010	4	0	4
2011	8	3	11
2012	10	1	11
2013	8	2	10
2014	12	4	16
2015	10	0	10
2016	6	3	9
2017	11	5	16
2018	8	2	10
2019	10	4	14
2020	10	1	11
2021	11	4	15
2022	7	0	7
2023	10	0	10
2024	10	1	11
2025	4	0	4
2026	1	0	1

Below are the most recent publications written about "Sepsis" by people in Profiles.

Li B, Gershengorn HB, Vail EA, Wunsch H, Walkey AJ, Law AC, Ko D, Ayalon N, Kearney CM, Bosch NA. Inotrope selection in mixed cardiogenic shock with sepsis: a comparative analysis between milrinone and dobutamine. Ann Am Thorac Soc. 2026 Feb 01; 23(2):252-260.

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Liesenfeld O, Arora S, Aufderheide TP, Clements CM, DeVos E, Fischer M, Giamarellos-Bourboulis EJ, House S, Humphries RL, Gill JK, Liu E, Mace SE, May L, Michelson E, Osborn TM, Panacek E, Rothman RE, Self WH, Smithline HA, Steingrub J, Van Heukelom P, Weissman A, Wilson M, Wolk DM, Wright DW, Buturovic L, Hasin-Brumshtein Y, Damaraju N, Lu C, Shak JR, Whitfield NN, Khatri P, Sweeney TE, Shapiro NI. Clinical validation of an AI-based blood testing device for diagnosis and prognosis of acute infection and sepsis. Nat Med. 2025 Dec; 31(12):4044-4054.

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Tripathi S, McGarvey J, Montgomery V, Gharpure VP, Kashyap R, Walkey A, Bansal V, Boman K, Kumar VK, Kissoon N. Prevalence of Sepsis as Defined by Phoenix Sepsis Definition Among Children With COVID-19. Hosp Pediatr. 2025 Jul 01; 15(7):554-562.

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O'Connor L, Hall M, Broach JP, Reznek MA. Evaluation of protocol fidelity for prehospital antibiotic administration. Acad Emerg Med. 2026 01; 33(1):e70015.

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Saha D, McAnena AP, Pandya A, Joshi G, Tai R. Septic and Aseptic Iliopsoas Bursitis - A Systematic Review of the Literature. Ortop Traumatol Rehabil. 2025 Feb 28; 27(1):1-8.

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Saha D, McAnena AP, Pandya A, Joshi G, Tai R. Bilateral Giant Septic Iliopsoas Bursitis in an Immunocompromised Patient: A Case Report. Ortop Traumatol Rehabil. 2024 Dec 31; 26(6):285-288.

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Dong T, Barasa L, Yu X, Ouyang W, Shao L, Quan C, Wang SH, Zhang J, Salmon M, Tsung A, Alam HB, Ma J, Thompson PR, Li Y. AFM41a: A Novel PAD2 Inhibitor for Sepsis Treatment-Efficacy and Mechanism. Int J Biol Sci. 2024; 20(13):5043-5055.

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Eaton TA, Kowalkowski M, Burns R, Tapp H, O'Hare K, Taylor SP. Pre-implementation planning for a sepsis intervention in a large learning health system: a qualitative study. BMC Health Serv Res. 2024 Aug 28; 24(1):996.

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Sartori LF, Tsemberis E, Hernandez T, Luchette K, Zhang D, Farooqi S, Bush J, McCann JC, Balamuth F, Weiss SL. Distinct mitochondrial respiration profiles in pediatric patients with febrile illness versus sepsis. Pediatr Res. 2025 Feb; 97(3):1127-1133.

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Iqbal F, Siva N, Kolibylu Raghupathy M, Edward S Lewis L, Barche A, Purkayastha J, S Nayak B. Probiotic effect in preterm neonates with sepsis - A systematic review protocol. F1000Res. 2022; 11:913.

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