Neoplastic Stem Cells

"Neoplastic Stem Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Highly proliferative, self-renewing, and colony-forming stem cells which give rise to NEOPLASMS.

Descriptor ID	D014411
MeSH Number(s)	A11.872.650
Concept/Terms	Neoplastic Stem Cells Neoplastic Stem Cells Cell, Neoplastic Stem Cells, Neoplastic Stem Neoplastic Stem Cell Stem Cell, Neoplastic Tumor Stem Cells Cell, Tumor Stem Cells, Tumor Stem Stem Cell, Tumor Stem Cells, Tumor Tumor Stem Cell Tumor Initiating Cells Cell, Tumor Initiating Cells, Tumor Initiating Initiating Cell, Tumor Initiating Cells, Tumor Tumor Initiating Cell Stem Cells, Neoplastic Cancer Stem Cells Cancer Stem Cells Cancer Stem Cell Cell, Cancer Stem Cells, Cancer Stem Stem Cell, Cancer Stem Cells, Cancer Neoplastic Colony-Forming Units Neoplastic Colony-Forming Units Colony-Forming Unit, Neoplastic Neoplastic Colony Forming Units Neoplastic Colony-Forming Unit Unit, Neoplastic Colony-Forming Units, Neoplastic Colony-Forming Colony-Forming Units, Neoplastic Colony Forming Units, Neoplastic

Below are MeSH descriptors whose meaning is more general than "Neoplastic Stem Cells".

Anatomy [A]
Cells [A11]
Stem Cells [A11.872]
Neoplastic Stem Cells [A11.872.650]

Below are MeSH descriptors whose meaning is related to "Neoplastic Stem Cells".

Below are MeSH descriptors whose meaning is more specific than "Neoplastic Stem Cells".

Neoplastic Stem Cells
Embryonal Carcinoma Stem Cells

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Neoplastic Stem Cells" by people in this website by year, and whether "Neoplastic Stem Cells" was a major or minor topic of these publications.

Bar chart showing 132 publications over 23 distinct years, with a maximum of 16 publications in 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
2002	0	1	1
2005	1	1	2
2006	2	0	2
2007	2	1	3
2008	4	2	6
2009	6	0	6
2010	13	0	13
2011	4	3	7
2012	14	2	16
2013	7	2	9
2014	7	4	11
2015	11	3	14
2016	5	3	8
2017	2	1	3
2018	3	4	7
2019	6	1	7
2020	2	2	4
2021	2	0	2
2022	0	3	3
2023	0	1	1
2024	3	1	4
2025	2	0	2

Below are the most recent publications written about "Neoplastic Stem Cells" by people in Profiles.

Li D, DeSouza N, Nguyen K, Li S. Leukaemia Stem Cells and Their Normal Stem Cell Counterparts Are Morphologically Distinguishable by Artificial Intelligence. J Cell Mol Med. 2025 May; 29(10):e70564.

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Oka T, Smith SS, Oliver-Garcia VS, Lee T, Son HG, Mortaja M, Azin M, Garza-Mayers AC, Huang JT, Nazarian RM, Horn TD, Demehri S. Epigenomic regulation of stemness contributes to the low immunogenicity of the most mutated human cancer. Cell Rep. 2025 May 27; 44(5):115561.

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Elaimy AL, El-Derany MO, James J, Wang Z, Pearson AN, Holcomb EA, Huber AK, Gij?n M, Bell HN, Sanghvi VR, Frankel TL, Su GL, Tapper EB, Tai AW, Ramnath N, Centonze CP, Dobrosotskaya I, Moeller JA, Bryant AK, Elliott DA, Choi E, Evans JR, Cuneo KC, Fitzgerald TJ, Wahl DR, Morgan MA, Chang DT, Wicha MS, Lawrence TS, Shah YM, Green MD. SLC4A11 mediates ammonia import and promotes cancer stemness in hepatocellular carcinoma. JCI Insight. 2024 Nov 08; 9(21).

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Shahzad U, Nikolopoulos M, Li C, Johnston M, Wang JJ, Sabha N, Varn FS, Riemenschneider A, Krumholtz S, Krishnamurthy PM, Smith CA, Karamchandani J, Watts JK, Verhaak RGW, Gallo M, Rutka JT, Das S. CASCADES, a novel SOX2 super-enhancer-associated long noncoding RNA, regulates cancer stem cell specification and differentiation in glioblastoma. Mol Oncol. 2025 Mar; 19(3):764-784.

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O'Connor KW, Kishimoto K, Kuzma IO, Wagner KP, Selway JS, Roderick JE, Karna KK, Gallagher KM, Hu K, Liu H, Li R, Brehm MA, Zhu LJ, Curtis DJ, Tremblay CS, Kelliher MA. The role of quiescent thymic progenitors in TAL/LMO2-induced T-ALL chemotolerance. Leukemia. 2024 May; 38(5):951-962.

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Ferrer-Diaz AI, Sinha G, Petryna A, Gonzalez-Bermejo R, Kenfack Y, Adetayo O, Patel SA, Hooda-Nehra A, Rameshwar P. Revealing role of epigenetic modifiers and DNA oxidation in cell-autonomous regulation of Cancer stem cells. Cell Commun Signal. 2024 02 12; 22(1):119.

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Nisco A, Carvalho TMA, Tolomeo M, Di Molfetta D, Leone P, Galluccio M, Medina M, Indiveri C, Reshkin SJ, Cardone RA, Barile M. Increased demand for FAD synthesis in differentiated and stem pancreatic cancer cells is accomplished by modulating FLAD1 gene expression: the inhibitory effect of Chicago Sky Blue. FEBS J. 2023 10; 290(19):4679-4694.

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Lee JS, Lero MW, Mercado-Matos J, Zhu S, Jo M, Tocheny CE, Morgan JS, Shaw LM. The insulin and IGF signaling pathway sustains breast cancer stem cells by IRS2/PI3K-mediated regulation of MYC. Cell Rep. 2022 12 06; 41(10):111759.

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George J, Chen Y, Abdelfattah N, Yamamoto K, Gallup TD, Adamson SI, Rybinski B, Srivastava A, Kumar P, Lee MG, Baskin DS, Jiang W, Choi JM, Flavahan W, Chuang JH, Kim BY, Xu J, Jung SY, Yun K. Cancer stem cells, not bulk tumor cells, determine mechanisms of resistance to SMO inhibitors. Cancer Res Commun. 2022 06; 2(6):402-416.

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Heffernan JM, McNamara JB, Vernon BL, Mehta S, Sirianni RW. PNJ scaffolds promote microenvironmental regulation of glioblastoma stem-like cell enrichment and radioresistance. Biomater Sci. 2022 Feb 01; 10(3):819-833.

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