Sodium Potassium Chloride Symporter Inhibitors

"Sodium Potassium Chloride Symporter Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Agents that inhibit SODIUM-POTASSIUM-CHLORIDE SYMPORTERS which are concentrated in the thick ascending limb at the junction of the LOOP OF HENLE and KIDNEY TUBULES, DISTAL. They act as DIURETICS. Excess use is associated with HYPOKALEMIA and HYPERGLYCEMIA.

Descriptor ID	D049994
MeSH Number(s)	D27.505.519.562.906 D27.505.696.560.500.931
Concept/Terms	Sodium Potassium Chloride Symporter Inhibitors Sodium Potassium Chloride Symporter Inhibitors Na-K-CL Symporter Inhibitors Inhibitors, Na-K-CL Symporter Na K CL Symporter Inhibitors Symporter Inhibitors, Na-K-CL Sodium Potassium Chloride Cotransporter Inhibitors Bumetanide Sensitive Na-K-Cl-Transporter Inhibitors Bumetanide Sensitive Na K Cl Transporter Inhibitors Loop Diuretics Loop Diuretics Diuretics, Loop High Ceiling Diuretics High Ceiling Diuretics Ceiling Diuretics, High Diuretics, High Ceiling

Below are MeSH descriptors whose meaning is more general than "Sodium Potassium Chloride Symporter Inhibitors".

Chemicals and Drugs [D]
Chemical Actions and Uses [D27]
Pharmacologic Actions [D27.505]
Molecular Mechanisms of Pharmacological Action [D27.505.519]
Membrane Transport Modulators [D27.505.519.562]
Sodium Potassium Chloride Symporter Inhibitors [D27.505.519.562.906]
Physiological Effects of Drugs [D27.505.696]
Natriuretic Agents [D27.505.696.560]
Diuretics [D27.505.696.560.500]
Sodium Potassium Chloride Symporter Inhibitors [D27.505.696.560.500.931]

Below are MeSH descriptors whose meaning is related to "Sodium Potassium Chloride Symporter Inhibitors".

Below are MeSH descriptors whose meaning is more specific than "Sodium Potassium Chloride Symporter Inhibitors".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Sodium Potassium Chloride Symporter Inhibitors" by people in this website by year, and whether "Sodium Potassium Chloride Symporter Inhibitors" was a major or minor topic of these publications.

Bar chart showing 11 publications over 9 distinct years, with a maximum of 2 publications in 2015 and 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2007	1	0	1
2008	0	1	1
2011	0	1	1
2013	0	1	1
2014	0	1	1
2015	2	0	2
2016	0	1	1
2018	1	1	2
2019	0	1	1

Below are the most recent publications written about "Sodium Potassium Chloride Symporter Inhibitors" by people in Profiles.

Pandhi P, Ter Maaten JM, Emmens JE, Struck J, Bergmann A, Cleland JG, Givertz MM, Metra M, O'Connor CM, Teerlink JR, Ponikowski P, Cotter G, Davison B, van Veldhuisen DJ, Voors AA. Clinical value of pre-discharge bio-adrenomedullin as a marker of residual congestion and high risk of heart failure hospital readmission. Eur J Heart Fail. 2020 04; 22(4):683-691.

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Luk A, Groarke JD, Desai AS, Mahmood SS, Gopal DM, Joyce E, Shah SP, Lindenfeld J, Stevenson L, Lakdawala NK. First spot urine sodium after initial diuretic identifies patients at high risk for adverse outcome after heart failure hospitalization. Am Heart J. 2018 09; 203:95-100.

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Kiernan MS, Stevens SR, Tang WHW, Butler J, Anstrom KJ, Birati EY, Grodin JL, Gupta D, Margulies KB, LaRue S, D?vila-Rom?n VG, Hernandez AF, de las Fuentes L. Determinants of Diuretic Responsiveness and Associated Outcomes During Acute Heart Failure Hospitalization: An Analysis From the NHLBI Heart Failure Network Clinical Trials. J Card Fail. 2018 Jul; 24(7):428-438.

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Khazanie P, Hammill BG, Patel CB, Kiernan MS, Cooper LB, Arnold SV, Fendler TJ, Spertus JA, Curtis LH, Hernandez AF. Use of Heart Failure Medical Therapies Among Patients With Left Ventricular Assist Devices: Insights From INTERMACS. J Card Fail. 2016 Sep; 22(9):672-9.

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Corapi KM, Wenger JB, Bhan I. Blood pressure and serum parathyroid hormone level--reply. JAMA Intern Med. 2015 Jun; 175(6):1069-70.

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Corapi KM, McMahon GM, Wenger JB, Seifter JL, Bhan I. Association of loop diuretic use with higher parathyroid hormone levels in patients with normal renal function. JAMA Intern Med. 2015 Jan; 175(1):137-8.

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Lafeuille MH, Grittner AM, Gravel J, Bailey RA, Martin S, Garber L, Sheng Duh M, Lefebvre P. Quality measure attainment in patients with type 2 diabetes mellitus. Am J Manag Care. 2014 Jan; 20(1 Suppl):s5-15.

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Kitsios GD, Mascari P, Ettunsi R, Gray AW. Co-administration of furosemide with albumin for overcoming diuretic resistance in patients with hypoalbuminemia: a meta-analysis. J Crit Care. 2014 Apr; 29(2):253-9.

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Freda BJ, Slawsky M, Mallidi J, Braden GL. Decongestive treatment of acute decompensated heart failure: cardiorenal implications of ultrafiltration and diuretics. Am J Kidney Dis. 2011 Dec; 58(6):1005-17.

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Wertheimer EV, Salicioni AM, Liu W, Trevino CL, Chavez J, Hern?ndez-Gonz?lez EO, Darszon A, Visconti PE. Chloride Is essential for capacitation and for the capacitation-associated increase in tyrosine phosphorylation. J Biol Chem. 2008 Dec 19; 283(51):35539-50.

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