"Ivermectin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mixture of mostly avermectin H2B1a (RN 71827-03-7) with some avermectin H2B1b (RN 70209-81-3), which are macrolides from STREPTOMYCES avermitilis. It binds glutamate-gated chloride channel to cause increased permeability and hyperpolarization of nerve and muscle cells. It also interacts with other CHLORIDE CHANNELS. It is a broad spectrum antiparasitic that is active against microfilariae of ONCHOCERCA VOLVULUS but not the adult form.
| Descriptor ID |
D007559
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| MeSH Number(s) |
D02.540.576.500.997
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Ivermectin".
Below are MeSH descriptors whose meaning is more specific than "Ivermectin".
This graph shows the total number of publications written about "Ivermectin" by people in this website by year, and whether "Ivermectin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 1 | 2 |
| 2014 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ivermectin" by people in Profiles.
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Reis G, Silva EASM, Silva DCM, Thabane L, Milagres AC, Ferreira TS, Dos Santos CVQ, Campos VHS, Nogueira AMR, de Almeida APFG, Callegari ED, Neto ADF, Savassi LCM, Simplicio MIC, Ribeiro LB, Oliveira R, Harari O, Forrest JI, Ruton H, Sprague S, McKay P, Guo CM, Rowland-Yeo K, Guyatt GH, Boulware DR, Rayner CR, Mills EJ. Effect of Early Treatment with Ivermectin among Patients with Covid-19. N Engl J Med. 2022 05 05; 386(18):1721-1731.
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Sahu KK, Mahagaokar K, Patel B, Winokur D, Suzuki S, Daly JS, Ramanathan M, Cerny J. Strongyloides stercoralis hyperinfection syndrome in mantle cell lymphoma in post-transplant setting. Ann Hematol. 2021 Apr; 100(4):1089-1091.
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Charuchaibovorn S, Sanprasert V, Sutthanont N, Hu Y, Abraham A, Ostroff GR, Aroian RV, Jaleta TG, Lok JB, Nuchprayoon S. Bacillus thuringiensis Cry5B is Active against Strongyloides stercoralis in vitro. Am J Trop Med Hyg. 2019 11; 101(5):1177-1182.
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Goldust M, Rezaee E, Raghifar R, Hemayat S. Comparing the efficacy of oral ivermectin vs malathion 0.5% lotion for the treatment of scabies. Skinmed. 2014 Sep-Oct; 12(5):284-7.
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Hu Y, Ellis BL, Yiu YY, Miller MM, Urban JF, Shi LZ, Aroian RV. An extensive comparison of the effect of anthelmintic classes on diverse nematodes. PLoS One. 2013; 8(7):e70702.
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Goldust M, Rezaee E, Raghifar R, Hemayat S. Treatment of scabies: the topical ivermectin vs. permethrin 2.5% cream. Ann Parasitol. 2013; 59(2):79-84.
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Goldust M, Rezaee E, Hemayat S. Treatment of scabies: Comparison of permethrin 5% versus ivermectin. J Dermatol. 2012 Jun; 39(6):545-7.
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Silverman J. Topical selamectin was 100% ineffective in eliminating Syphacia infections in rats and mice. J Am Assoc Lab Anim Sci. 2006 Sep; 45(5):7; author reply 7.
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Smith H, Campbell WC. Effect of ivermectin on Caenorhabditis elegans larvae previously exposed to alcoholic immobilization. J Parasitol. 1996 Feb; 82(1):187-8.
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Urban JF, Romanowski RD, Steele NC. Influence of helminth parasite exposure and strategic application of anthelmintics on the development of immunity and growth of swine. J Anim Sci. 1989 Jul; 67(7):1668-77.