Ivermectin

"Ivermectin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A mixture of mostly avermectin H2B1a (RN 71827-03-7) with some avermectin H2B1b (RN 70209-81-3), which are macrolides from STREPTOMYCES avermitilis. It binds glutamate-gated chloride channel to cause increased permeability and hyperpolarization of nerve and muscle cells. It also interacts with other CHLORIDE CHANNELS. It is a broad spectrum antiparasitic that is active against microfilariae of ONCHOCERCA VOLVULUS but not the adult form.

Descriptor ID	D007559
MeSH Number(s)	D02.540.576.500.997
Concept/Terms	Ivermectin Ivermectin Stromectol Stromectol Mectizan Mectizan MK-933 MK-933 MK 933 MK933 Eqvalan Eqvalan Ivomec Ivomec

Below are MeSH descriptors whose meaning is more general than "Ivermectin".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Lactones [D02.540]
Polyketides [D02.540.576]
Macrolides [D02.540.576.500]
Ivermectin [D02.540.576.500.997]

Below are MeSH descriptors whose meaning is related to "Ivermectin".

Below are MeSH descriptors whose meaning is more specific than "Ivermectin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Ivermectin" by people in this website by year, and whether "Ivermectin" was a major or minor topic of these publications.

Bar chart showing 21 publications over 11 distinct years, with a maximum of 4 publications in 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2012	1	0	1
2013	1	1	2
2014	1	0	1
2015	1	0	1
2018	1	0	1
2019	3	1	4
2020	1	2	3
2021	1	2	3
2022	2	1	3
2023	0	1	1
2025	0	1	1

Below are the most recent publications written about "Ivermectin" by people in Profiles.

Caetano MC, Emmerick ICM, Campos MR, Pires DC, Wirtz VJ, Luiza VL. Effect of Covid-19 pandemic on azithromycin, chloroquine/hydroxychloroquine and ivermectin outpatient consumption in Brazil: a joinpoint regression analysis. BMC Public Health. 2025 Apr 03; 25(1):1250.

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Lake SJ, Engelman D, Zinihite J, Sokana O, Boara D, Nasi T, Gorae C, Osti MH, Phelan S, Parnaby M, Grobler AC, Schuster T, Andrews R, Whitfeld MJ, Marks M, Romani L, Steer AC, Kaldor JM. One versus two doses of ivermectin-based mass drug administration for the control of scabies: A cluster randomised non-inferiority trial. PLoS Negl Trop Dis. 2023 03; 17(3):e0011207.

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Marks M, McVernon J, McCarthy JS, Enbiale W, Hanna C, Chosidow O, Engelman D, Asiedu K, Steer A. Diagnostics to support the control of scabies-Development of two target product profiles. PLoS Negl Trop Dis. 2022 08; 16(8):e0010556.

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Reis G, Silva EASM, Silva DCM, Thabane L, Milagres AC, Ferreira TS, Dos Santos CVQ, Campos VHS, Nogueira AMR, de Almeida APFG, Callegari ED, Neto ADF, Savassi LCM, Simplicio MIC, Ribeiro LB, Oliveira R, Harari O, Forrest JI, Ruton H, Sprague S, McKay P, Guo CM, Rowland-Yeo K, Guyatt GH, Boulware DR, Rayner CR, Mills EJ. Effect of Early Treatment with Ivermectin among Patients with Covid-19. N Engl J Med. 2022 05 05; 386(18):1721-1731.

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Mow M, Thean LJ, Parnaby M, Mani J, Rafai E, Sahukhan A, Kama M, Tuicakau M, Kado J, Romani L, Engelman D, Whitfeld M, Kaldor J, Steer A, Carvalho N. Costs of mass drug administration for scabies in Fiji. PLoS Negl Trop Dis. 2022 02; 16(2):e0010147.

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Hardy M, Samuela J, Kama M, Tuicakau M, Romani L, Whitfeld MJ, King CL, Weil GJ, Schuster T, Grobler AC, Engelman D, Robinson LJ, Kaldor JM, Steer AC. Community control strategies for scabies: A cluster randomised noninferiority trial. PLoS Med. 2021 11; 18(11):e1003849.

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Engelman D, Marks M, Steer AC, Beshah A, Biswas G, Chosidow O, Coffeng LE, Lardizabal Dofitas B, Enbiale W, Fallah M, Gasimov E, Hopkins A, Jacobson J, Kaldor JM, Ly F, Mackenzie CD, McVernon J, Parnaby M, Rainima-Qaniuci M, Sokana O, Sankara D, Yotsu R, Yajima A, Cantey PT. A framework for scabies control. PLoS Negl Trop Dis. 2021 09; 15(9):e0009661.

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Jittamala P, Monteiro W, Smit MR, Pedrique B, Specht S, Chaccour CJ, Dard C, Del Giudice P, Khieu V, Maruani A, Failoc-Rojas VE, S?ez-de-Ocariz M, Soriano-Arandes A, Piquero-Casals J, Faisant A, Brenier-Pinchart MP, Wimmersberger D, Coulibaly JT, Keiser J, Boralevi F, Sokana O, Marks M, Engelman D, Romani L, Steer AC, von Seidlein L, White NJ, Harriss E, Stepniewska K, Humphreys GS, Kennon K, Guerin PJ, Kobylinski KC. A systematic review and an individual patient data meta-analysis of ivermectin use in children weighing less than fifteen kilograms: Is it time to reconsider the current contraindication? PLoS Negl Trop Dis. 2021 03; 15(3):e0009144.

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Lake SJ, Phelan SL, Engelman D, Sokana O, Nasi T, Boara D, Gorae C, Schuster T, Grobler AC, Osti MH, Andrews R, Marks M, Whitfeld MJ, Romani L, Kaldor J, Steer A. Protocol for a cluster-randomised non-inferiority trial of one versus two doses of ivermectin for the control of scabies using a mass drug administration strategy (the RISE study). BMJ Open. 2020 08 30; 10(8):e037305.

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Sahu KK, Mahagaokar K, Patel B, Winokur D, Suzuki S, Daly JS, Ramanathan M, Cerny J. Strongyloides stercoralis hyperinfection syndrome in mantle cell lymphoma in post-transplant setting. Ann Hematol. 2021 Apr; 100(4):1089-1091.

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