"Caspase 10" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A long pro-domain caspase that contains a death effector domain in its pro-domain region. Activation of this enzyme can occur via the interaction of its N-terminal death effector domain with DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS. Caspase 10 plays a role in APOPTOSIS by cleaving and activating EFFECTOR CASPASES. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.
- Caspase 10a
- Mch4 Protease
- Protease, Mch4
- Caspase 10-a
- Caspase 10 a
Below are MeSH descriptors whose meaning is more general than "Caspase 10".
Below are MeSH descriptors whose meaning is more specific than "Caspase 10".
This graph shows the total number of publications written about "Caspase 10" by people in this website by year, and whether "Caspase 10" was a major or minor topic of these publications.
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Below are the most recent publications written about "Caspase 10" by people in Profiles.
Takita J, Yang HW, Chen YY, Hanada R, Yamamoto K, Teitz T, Kidd V, Hayashi Y. Allelic imbalance on chromosome 2q and alterations of the caspase 8 gene in neuroblastoma. Oncogene. 2001 Jul 19; 20(32):4424-32.
Wang J, Zheng L, Lobito A, Chan FK, Dale J, Sneller M, Yao X, Puck JM, Straus SE, Lenardo MJ. Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II. Cell. 1999 Jul 09; 98(1):47-58.