Below are the most recent publications written about "Caspase 8" by people in Profiles.
-
Winther KG, Schneider J, Haas G, Christensen AH, Goyal S, Luo W, Wei Z, Liu J, Kj?ge K, Enghild JJ, Meignin C, Silverman N, Cai H, Imler JL, Hartmann R. FADD is recruited to activated STING oligomers to initiate caspase-mediated NF-?B activation in Drosophila melanogaster. EMBO J. 2026 May; 45(9):2965-2990.
-
Volkert I, Grube J, Woitok MM, Mohamed MR, Edlund K, Duda JC, Dietrich J, Schneider U, Yin G, Lin C, Erschfeld S, Berger H, Candels L, Davis RJ, Bartneck M, K?hnel MP, Guillot A, Schneider KM, Schneider CV, Jonigk D, Rahnenf?hrer J, Tacke F, Hengstler J, Trautwein C. Selective genetic inactivation of Caspase 8 in hepatocytes ameliorates progression of MASH following Jnk deficiency. Hepatology. 2026 Feb 01; 83(2):344-361.
-
Zhang B, Orning P, Lehman JW, Dinis A, Torres-Ulloa L, Elling R, Kelliher MA, Bertin J, Proulx MK, Goguen JD, Ryan L, Kandasamy RK, Espevik T, Pai AA, Fitzgerald KA, Lien E. Raver1 links Ripk1 RNA splicing to caspase-8-mediated pyroptotic cell death, inflammation, and pathogen resistance. Proc Natl Acad Sci U S A. 2025 Feb 18; 122(7):e2420802122.
-
Jena KK, Mambu J, Boehmer D, Sposito B, Millet V, de Sousa Casal J, Muendlein HI, Spreafico R, Fenouil R, Spinelli L, Wurbel S, Riquier C, Galland F, Naquet P, Chasson L, Elkins M, Mitsialis V, Ketelut-Carneiro N, Bugda Gwilt K, Thiagarajah JR, Ruan HB, Lin Z, Lien E, Shao F, Chou J, Poltorak A, Ordovas-Montanes J, Fitzgerald KA, Snapper SB, Broggi A, Zanoni I. Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair. Cell. 2024 Dec 26; 187(26):7533-7550.e23.
-
Lentini G, Fam? A, De Gaetano GV, Coppolino F, Mahjoub AK, Ryan L, Lien E, Espevik T, Beninati C, Teti G. Caspase-8 inhibition improves the outcome of bacterial infections in mice by promoting neutrophil activation. Cell Rep Med. 2023 07 18; 4(7):101098.
-
Lei X, Chen Y, Lien E, Fitzgerald KA. MLKL-Driven Inflammasome Activation and Caspase-8 Mediate Inflammatory Cell Death in Influenza A Virus Infection. mBio. 2023 04 25; 14(2):e0011023.
-
Soni IV, Hardy JA. Caspase-9 Activation of Procaspase-3 but Not Procaspase-6 Is Based on the Local Context of Cleavage Site Motifs and on Sequence. Biochemistry. 2021 09 21; 60(37):2824-2835.
-
M?ller K, Honcharova-Biletska H, Koppe C, Egger M, Chan LK, Schneider AT, K?sgens L, B?hm F, Boege Y, Healy ME, Schmitt J, Comtesse S, Castoldi M, Preisinger C, Szydlowska M, Focaccia E, Gaisa NT, Loosen SH, J?rs S, Tacke F, Roderburg C, Keitel V, Bode JG, Boor P, Davis RJ, Longerich T, Geisler F, Heikenwalder M, Weber A, Vucur M, Luedde T. JNK signaling prevents biliary cyst formation through a CASPASE-8-dependent function of RIPK1 during aging. Proc Natl Acad Sci U S A. 2021 03 23; 118(12).
-
Pereira LMN, Assis PA, de Ara?jo NM, Durso DF, Junqueira C, Ata?de MA, Pereira DB, Lien E, Fitzgerald KA, Zamboni DS, Golenbock DT, Gazzinelli RT. Caspase-8 mediates inflammation and disease in rodent malaria. Nat Commun. 2020 09 14; 11(1):4596.
-
Orning P, Lien E. Multiple roles of caspase-8 in cell death, inflammation, and innate immunity. J Leukoc Biol. 2021 01; 109(1):121-141.