"Prolactin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A lactogenic hormone secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). It is a polypeptide of approximately 23 kD. Besides its major action on lactation, in some species prolactin exerts effects on reproduction, maternal behavior, fat metabolism, immunomodulation and osmoregulation. Prolactin receptors are present in the mammary gland, hypothalamus, liver, ovary, testis, and prostate.
Descriptor ID |
D011388
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MeSH Number(s) |
D06.472.699.322.576.773 D06.472.699.631.525.525 D12.644.548.691.525.525
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Concept/Terms |
Prolactin- Prolactin
- Mammotropic Hormone, Pituitary
- Hormone, Pituitary Mammotropic
- Pituitary Mammotropic Hormone
- PRL (Prolactin)
- Lactogenic Hormone, Pituitary
- Hormone, Pituitary Lactogenic
- Pituitary Lactogenic Hormone
- Mammotropin
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Below are MeSH descriptors whose meaning is more general than "Prolactin".
Below are MeSH descriptors whose meaning is more specific than "Prolactin".
This graph shows the total number of publications written about "Prolactin" by people in this website by year, and whether "Prolactin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 2 | 2 |
1996 | 0 | 1 | 1 |
1997 | 0 | 3 | 3 |
1998 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2003 | 1 | 2 | 3 |
2004 | 1 | 0 | 1 |
2005 | 0 | 1 | 1 |
2006 | 2 | 0 | 2 |
2008 | 0 | 1 | 1 |
2010 | 1 | 2 | 3 |
2011 | 0 | 1 | 1 |
2013 | 1 | 0 | 1 |
2014 | 1 | 1 | 2 |
2016 | 1 | 0 | 1 |
2019 | 0 | 1 | 1 |
2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Prolactin" by people in Profiles.
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Li G, Young CH, Snow B, Christensen AO, Demoruelle MK, Nemmara VV, Thompson PR, Rothfuss HM, Cherrington BD. Identification and Characterization of the Lactating Mouse Mammary Gland Citrullinome. Int J Mol Sci. 2020 Apr 10; 21(7).
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Rajhans P, Goin-Kochel RP, Strathearn L, Kim S. It takes two! Exploring sex differences in parenting neurobiology and behaviour. J Neuroendocrinol. 2019 09; 31(9):e12721.
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Reeves KW, Okereke OI, Qian J, Tworoger SS, Rice MS, Hankinson SE. Antidepressant use and circulating prolactin levels. Cancer Causes Control. 2016 07; 27(7):853-61.
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Tworoger SS, Zhang X, Eliassen AH, Qian J, Colditz GA, Willett WC, Rosner BA, Kraft P, Hankinson SE. Inclusion of endogenous hormone levels in risk prediction models of postmenopausal breast cancer. J Clin Oncol. 2014 Oct 01; 32(28):3111-7.
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Hartwell HJ, Petrosky KY, Fox JG, Horseman ND, Rogers AB. Prolactin prevents hepatocellular carcinoma by restricting innate immune activation of c-Myc in mice. Proc Natl Acad Sci U S A. 2014 Aug 05; 111(31):11455-60.
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Song X, Fan X, Zhang J, Zheng H, Li X, Pang L, Chen X, Zhang W, Harrington A, Ziedonis D, Lv L. Prolactin serum levels correlate with inflammatory status in drug-na?ve first-episode schizophrenia. World J Biol Psychiatry. 2014 Sep; 15(7):546-52.
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Breves JP, McCormick SD, Karlstrom RO. Prolactin and teleost ionocytes: new insights into cellular and molecular targets of prolactin in vertebrate epithelia. Gen Comp Endocrinol. 2014 Jul 01; 203:21-8.
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Breves JP, Serizier SB, Goffin V, McCormick SD, Karlstrom RO. Prolactin regulates transcription of the ion uptake Na+/Cl- cotransporter (ncc) gene in zebrafish gill. Mol Cell Endocrinol. 2013 Apr 30; 369(1-2):98-106.
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Scully S, Yan W, Bentley B, Cao QJ, Shao R. Inhibitory activity of YKL-40 in mammary epithelial cell differentiation and polarization induced by lactogenic hormones: a role in mammary tissue involution. PLoS One. 2011; 6(10):e25819.
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Cao J, Patisaul HB, Petersen SL. Aryl hydrocarbon receptor activation in lactotropes and gonadotropes interferes with estradiol-dependent and -independent preprolactin, glycoprotein alpha and luteinizing hormone beta gene expression. Mol Cell Endocrinol. 2011 Feb 20; 333(2):151-9.