 Phosphatidylinositols
"Phosphatidylinositols" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Derivatives of phosphatidic acids in which the phosphoric acid is bound in ester linkage to the hexahydroxy alcohol, myo-inositol. Complete hydrolysis yields 1 mole of glycerol, phosphoric acid, myo-inositol, and 2 moles of fatty acids.
| Descriptor ID |
D010716
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| MeSH Number(s) |
D10.570.755.375.760.400.942
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| Concept/Terms |
Phosphatidylinositols- Phosphatidylinositols
- Inositol Phosphoglycerides
- Phosphoglycerides, Inositol
- Inositol Phospholipids
- Phospholipids, Inositol
- Phosphatidyl Inositol
- Inositol, Phosphatidyl
- Phosphoinositides
- PtdIns
- Inositide Phospholipids
- Phospholipids, Inositide
- Phosphatidylinositol
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Below are MeSH descriptors whose meaning is more general than "Phosphatidylinositols".
Below are MeSH descriptors whose meaning is more specific than "Phosphatidylinositols".
This graph shows the total number of publications written about "Phosphatidylinositols" by people in this website by year, and whether "Phosphatidylinositols" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1983 | 1 | 0 | 1 | | 1986 | 0 | 1 | 1 | | 1987 | 1 | 0 | 1 | | 1988 | 1 | 0 | 1 | | 1989 | 2 | 0 | 2 | | 1990 | 1 | 0 | 1 | | 1991 | 1 | 1 | 2 | | 1992 | 1 | 0 | 1 | | 1995 | 0 | 1 | 1 | | 1996 | 0 | 2 | 2 | | 1997 | 0 | 1 | 1 | | 1999 | 1 | 1 | 2 | | 2000 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2004 | 2 | 0 | 2 | | 2005 | 2 | 0 | 2 | | 2006 | 2 | 1 | 3 | | 2007 | 1 | 0 | 1 | | 2008 | 1 | 1 | 2 | | 2010 | 0 | 2 | 2 | | 2011 | 0 | 1 | 1 | | 2012 | 0 | 2 | 2 | | 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Phosphatidylinositols" by people in Profiles.
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Jiang Z, Redfern RE, Isler Y, Ross AH, Gericke A. Cholesterol stabilizes fluid phosphoinositide domains. Chem Phys Lipids. 2014 Sep; 182:52-61.
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Shenoy S, Shekhar P, Heinrich F, Daou MC, Gericke A, Ross AH, Lösche M. Membrane association of the PTEN tumor suppressor: molecular details of the protein-membrane complex from SPR binding studies and neutron reflection. PLoS One. 2012; 7(4):e32591.
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Hehnly H, Doxsey S. Polarity sets the stage for cytokinesis. Mol Biol Cell. 2012 Jan; 23(1):7-11.
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Morita YS, Fukuda T, Sena CB, Yamaryo-Botte Y, McConville MJ, Kinoshita T. Inositol lipid metabolism in mycobacteria: biosynthesis and regulatory mechanisms. Biochim Biophys Acta. 2011 Jun; 1810(6):630-41.
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Redfern RE, Daou MC, Li L, Munson M, Gericke A, Ross AH. A mutant form of PTEN linked to autism. Protein Sci. 2010 Oct; 19(10):1948-56.
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Morita YS, Yamaryo-Botte Y, Miyanagi K, Callaghan JM, Patterson JH, Crellin PK, Coppel RL, Billman-Jacobe H, Kinoshita T, McConville MJ. Stress-induced synthesis of phosphatidylinositol 3-phosphate in mycobacteria. J Biol Chem. 2010 May 28; 285(22):16643-50.
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Crellin PK, Kovacevic S, Martin KL, Brammananth R, Morita YS, Billman-Jacobe H, McConville MJ, Coppel RL. Mutations in pimE restore lipoarabinomannan synthesis and growth in a Mycobacterium smegmatis lpqW mutant. J Bacteriol. 2008 May; 190(10):3690-9.
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Redfern RE, Redfern D, Furgason ML, Munson M, Ross AH, Gericke A. PTEN phosphatase selectively binds phosphoinositides and undergoes structural changes. Biochemistry. 2008 Feb 19; 47(7):2162-71.
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DiNitto JP, Delprato A, Gabe Lee MT, Cronin TC, Huang S, Guilherme A, Czech MP, Lambright DG. Structural basis and mechanism of autoregulation in 3-phosphoinositide-dependent Grp1 family Arf GTPase exchange factors. Mol Cell. 2007 Nov 30; 28(4):569-83.
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Morita YS, Sena CB, Waller RF, Kurokawa K, Sernee MF, Nakatani F, Haites RE, Billman-Jacobe H, McConville MJ, Maeda Y, Kinoshita T. PimE is a polyprenol-phosphate-mannose-dependent mannosyltransferase that transfers the fifth mannose of phosphatidylinositol mannoside in mycobacteria. J Biol Chem. 2006 Sep 1; 281(35):25143-55.
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