Lipopolysaccharides

"Lipopolysaccharides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)

Descriptor ID	D008070
MeSH Number(s)	D09.400.500 D09.698.718.450 D10.494 D23.050.161.616.525 D23.946.123.329.500
Concept/Terms	Lipopolysaccharides Lipopolysaccharides Lipoglycans

Below are MeSH descriptors whose meaning is more general than "Lipopolysaccharides".

Chemicals and Drugs [D]
Carbohydrates [D09]
Glycoconjugates [D09.400]
Lipopolysaccharides [D09.400.500]
Polysaccharides [D09.698]
Polysaccharides, Bacterial [D09.698.718]
Lipopolysaccharides [D09.698.718.450]
Lipids [D10]
Lipopolysaccharides [D10.494]
Biological Factors [D23]
Antigens [D23.050]
Antigens, Bacterial [D23.050.161]
Polysaccharides, Bacterial [D23.050.161.616]
Lipopolysaccharides [D23.050.161.616.525]
Toxins, Biological [D23.946]
Bacterial Toxins [D23.946.123]
Endotoxins [D23.946.123.329]
Lipopolysaccharides [D23.946.123.329.500]

Below are MeSH descriptors whose meaning is related to "Lipopolysaccharides".

Below are MeSH descriptors whose meaning is more specific than "Lipopolysaccharides".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Lipopolysaccharides" by people in this website by year, and whether "Lipopolysaccharides" was a major or minor topic of these publications.

Bar chart showing 424 publications over 31 distinct years, with a maximum of 26 publications in 2002

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	4	3	7
1996	6	5	11
1997	6	4	10
1998	8	3	11
1999	13	9	22
2000	8	3	11
2001	4	11	15
2002	8	18	26
2003	7	8	15
2004	6	10	16
2005	6	15	21
2006	4	19	23
2007	1	16	17
2008	3	9	12
2009	5	11	16
2010	7	6	13
2011	7	10	17
2012	10	8	18
2013	4	13	17
2014	3	13	16
2015	2	9	11
2016	5	8	13
2017	8	7	15
2018	4	6	10
2019	4	12	16
2020	4	10	14
2021	0	9	9
2022	0	5	5
2023	0	3	3
2024	3	6	9
2025	1	4	5

Below are the most recent publications written about "Lipopolysaccharides" by people in Profiles.

Krause K, Franch Arroyo S, Ugolini M, Kueck T, Sullivan TJ, G?lvez EJC, Muenzner M, Goosmann C, Brinkmann V, Frese CK, Alagesan K, Vierbuchen T, Heine H, Resch U, Sander LE, Charpentier E. Streptococcus pyogenes EVs induce the alternative inflammasome via caspase-4/-5 in human monocytes. EMBO Rep. 2025 Oct; 26(19):4847-4885.

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Gorasiya S, Mushi J, Yoganathan S, Barasa L, Pekson R, Ashby CR, Reznik SE. N,N-Diethylacetamide and N,N-Dipropylacetamide inhibit the NF-kB pathway in in vitro, ex vivo and in vivo models of inflammation-induced preterm birth. Sci Rep. 2025 Aug 14; 15(1):29861.

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Kurt-Jones EA, Gulati S, King M, de Oliveira RB, Rice PA, Zheng B, Shaughnessy J, Edwards JL, Hertzog PJ, Ram S, Golenbock DT. Interferon-epsilon, an estrogen-induced type I interferon, is uniquely exploited by Neisseria gonorrhoeae via effects on sialic acid metabolism. Cell Host Microbe. 2025 Jul 09; 33(7):1133-1145.e4.

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Grace PS, Peters JM, Sixsmith J, Lu R, Irvine EB, Luedeman C, Fenderson BA, Vickers A, Slein MD, McKitrick T, Wei MH, Cummings RD, Wallace A, Cavacini LA, Choudhary A, Proulx MK, Sundling C, K?llenius G, Reljic R, Ernst JD, Casadevall A, Locht C, Pinter A, Sassetti CM, Bryson BD, Fortune SM, Alter G. Antibody-Fab and -Fc features promote Mycobacterium tuberculosis restriction. Immunity. 2025 Jun 10; 58(6):1586-1597.e5.

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Go MY, Kim J, Jeon CY, Kim M, Shin DW. Pinitol Improves Lipopolysaccharide-Induced Cellular Damage in Human Dermal Microvascular Endothelial Cells. Molecules. 2025 Mar 28; 30(7).

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Liu Y, Zhou Y, Hao B, Wu Z, Gao M, Liu L, Xia Q, Zheng K, Yang S, Tang Y, Gong M, Feng C, Diao H, Tan Y, Zheng H. Inhibition of ferroptosis attenuate lipopolysaccharide-induced early pregnancy loss by protecting against decidual damage of stromal cells. Biochem Biophys Res Commun. 2024 12 03; 736:150904.

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Joshi R, Brezani V, Mey GM, Guix?-Muntet S, Ortega-Ribera M, Zhuang Y, Zivny A, Werneburg S, Gracia-Sancho J, Szabo G. IRF3 regulates neuroinflammatory responses and the expression of genes associated with Alzheimer's disease. J Neuroinflammation. 2024 Aug 30; 21(1):212.

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Owona BA, Mary A, Messi AN, Ravichandran KA, Mbing JN, Pegnyemb E, Moundipa PF, Heneka MT. Biflavonoid Methylchamaejasmin and Khaya grandifoliola?Extract Inhibit NLRP3 Inflammasome in THP-1 Cell Model of Neuroinflammation. Mol Neurobiol. 2025 Feb; 62(2):1605-1619.

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Stolarski AE, Lai JJ, Kim J, Rock KL, Remick D. GENETIC ABLATION OF THE C-TYPE LECTIN RECEPTOR CLEC2D INCREASES PERITONITIS MORTALITY, INFLAMMATION, AND PHYSIOLOGY WITHOUT DIMINISHING ORGAN INJURY. Shock. 2024 09 01; 62(3):437-446.

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Kumari A, Caliz AD, Yoo HJ, Kant S, Vertii A. TNF-alpha promotes cilia elongation via mixed lineage kinases signaling in mouse fibroblasts and human RPE-1 cells. Cytoskeleton (Hoboken). 2024 Nov; 81(11):639-647.

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