"Lipofuscin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A naturally occurring lipid pigment with histochemical characteristics similar to ceroid. It accumulates in various normal tissues and apparently increases in quantity with age.
| Descriptor ID |
D008062
|
| MeSH Number(s) |
D10.460 D23.767.550
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Lipofuscin".
Below are MeSH descriptors whose meaning is more specific than "Lipofuscin".
This graph shows the total number of publications written about "Lipofuscin" by people in this website by year, and whether "Lipofuscin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lipofuscin" by people in Profiles.
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Stillman JM, Mendes Lopes F, Lin JP, Hu K, Reich DS, Schafer DP. Lipofuscin-like autofluorescence within microglia and its impact on studying microglial engulfment. Nat Commun. 2023 11 03; 14(1):7060.
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Cheng SY, Cipi J, Ma S, Hafler BP, Kanadia RN, Brush RS, Agbaga MP, Punzo C. Altered photoreceptor metabolism in mouse causes late stage age-related macular degeneration-like pathologies. Proc Natl Acad Sci U S A. 2020 06 09; 117(23):13094-13104.
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Brandstetter C, Mohr LK, Latz E, Holz FG, Krohne TU. Light induces NLRP3 inflammasome activation in retinal pigment epithelial cells via lipofuscin-mediated photooxidative damage. J Mol Med (Berl). 2015 Aug; 93(8):905-16.
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Parson SJ, Russell SD, Bennett MK, Dunn JM, Gilotra NA, Rao S, Harrington C, Freitag TB, Foster MC, Halushka MK. Increased lipofuscin on endomyocardial biopsy predicts greater cardiac improvement in adolescents and young adults. Cardiovasc Pathol. 2012 Jul-Aug; 21(4):317-23.
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Zhao L, Spassieva SD, Jucius TJ, Shultz LD, Shick HE, Macklin WB, Hannun YA, Obeid LM, Ackerman SL. A deficiency of ceramide biosynthesis causes cerebellar purkinje cell neurodegeneration and lipofuscin accumulation. PLoS Genet. 2011 May; 7(5):e1002063.
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Lee H, Carlin AM, Ormsby AH, Lee MW. Brown bowel syndrome secondary to jejunoileal bypass: the first case report. Obes Surg. 2009 Aug; 19(8):1176-9.
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Kiefer CR, McKenney JB, Trainor JF, Lambrecht RW, Bonkovsky HL, Lifshitz LM, Valeri CR, Snyder LM. Porphyrin loading of lipofuscin granules in inflamed striated muscle. Am J Pathol. 1998 Sep; 153(3):703-8.