Ribonucleoprotein, U5 Small Nuclear
"Ribonucleoprotein, U5 Small Nuclear" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U5 snRNP along with U4-U6 snRNP preassemble into a single 25S particle that binds to the U1 and U2 snRNPs and the substrate to form SPLICEOSOMES.
| Descriptor ID |
D017415
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| MeSH Number(s) |
D12.776.157.725.500.875.620 D12.776.157.725.829.375 D12.776.664.962.500.875.620 D12.776.664.962.829.375
|
| Concept/Terms |
Ribonucleoprotein, U5 Small Nuclear- Ribonucleoprotein, U5 Small Nuclear
- Small Nuclear Ribonucleoproteins, U5
- Ribonucleoproteins, Small, U5
- U5 snRNP
- U5 Small Nuclear Ribonucleoproteins
|
Below are MeSH descriptors whose meaning is more general than "Ribonucleoprotein, U5 Small Nuclear".
Below are MeSH descriptors whose meaning is more specific than "Ribonucleoprotein, U5 Small Nuclear".
This graph shows the total number of publications written about "Ribonucleoprotein, U5 Small Nuclear" by people in this website by year, and whether "Ribonucleoprotein, U5 Small Nuclear" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2011 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ribonucleoprotein, U5 Small Nuclear" by people in Profiles.
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Goos JAC, Swagemakers SMA, Twigg SRF, van Dooren MF, Hoogeboom AJM, Beetz C, G?nther S, Magielsen FJ, Ockeloen CW, A Ramos-Arroyo M, Pfundt R, Yntema HG, van der Spek PJ, Stanier P, Wieczorek D, Wilkie AOM, van den Ouweland AMW, Mathijssen IMJ, Hurst JA. Identification of causative variants in TXNL4A in Burn-McKeown syndrome and isolated choanal atresia. Eur J Hum Genet. 2017 10; 25(10):1126-1133.
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Hoskins AA, Friedman LJ, Gallagher SS, Crawford DJ, Anderson EG, Wombacher R, Ramirez N, Cornish VW, Gelles J, Moore MJ. Ordered and dynamic assembly of single spliceosomes. Science. 2011 Mar 11; 331(6022):1289-95.
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O'Brien K, Matlin AJ, Lowell AM, Moore MJ. The biflavonoid isoginkgetin is a general inhibitor of Pre-mRNA splicing. J Biol Chem. 2008 Nov 28; 283(48):33147-54.
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Bellare P, Small EC, Huang X, Wohlschlegel JA, Staley JP, Sontheimer EJ. A role for ubiquitin in the spliceosome assembly pathway. Nat Struct Mol Biol. 2008 May; 15(5):444-51.
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Bellare P, Kutach AK, Rines AK, Guthrie C, Sontheimer EJ. Ubiquitin binding by a variant Jab1/MPN domain in the essential pre-mRNA splicing factor Prp8p. RNA. 2006 Feb; 12(2):292-302.
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Jurica MS, Sousa D, Moore MJ, Grigorieff N. Three-dimensional structure of C complex spliceosomes by electron microscopy. Nat Struct Mol Biol. 2004 Mar; 11(3):265-9.
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Wyatt JR, Sontheimer EJ, Steitz JA. Site-specific cross-linking of mammalian U5 snRNP to the 5' splice site before the first step of pre-mRNA splicing. Genes Dev. 1992 Dec; 6(12B):2542-53.