T-Cell Intracellular Antigen-1
"T-Cell Intracellular Antigen-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An RNA-binding protein characterized by three RNA RECOGNITION MOTIFS. It binds to AU RICH ELEMENTS in the 3'-untranslated regions of mRNA and regulates alternative pre-RNA splicing and mRNA translation; it may also function in APOPTOSIS. Mutations in the TIA-1 gene are associated with WELANDER DISTAL MYOPATHY.
| Descriptor ID |
D000074019
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| MeSH Number(s) |
D12.776.157.725.452.750 D12.776.157.725.813.937 D12.776.157.725.829.875 D12.776.664.962.452.750 D12.776.664.962.813.937 D12.776.664.962.829.875
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| Concept/Terms |
T-Cell Intracellular Antigen-1- T-Cell Intracellular Antigen-1
- Intracellular Antigen-1, T-Cell
- T Cell Intracellular Antigen 1
- T-Cell-Restricted Intracellular Antigen-1
- Intracellular Antigen-1, T-Cell-Restricted
- T Cell Restricted Intracellular Antigen 1
- RNA-Binding Protein TIA-1
- RNA Binding Protein TIA 1
- TIA-1, RNA-Binding Protein
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Below are MeSH descriptors whose meaning is more general than "T-Cell Intracellular Antigen-1".
Below are MeSH descriptors whose meaning is more specific than "T-Cell Intracellular Antigen-1".
This graph shows the total number of publications written about "T-Cell Intracellular Antigen-1" by people in this website by year, and whether "T-Cell Intracellular Antigen-1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "T-Cell Intracellular Antigen-1" by people in Profiles.
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Maziuk BF, Apicco DJ, Cruz AL, Jiang L, Ash PEA, da Rocha EL, Zhang C, Yu WH, Leszyk J, Abisambra JF, Li H, Wolozin B. RNA binding proteins co-localize with small tau inclusions in tauopathy. Acta Neuropathol Commun. 2018 08 01; 6(1):71.
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Zheng D, Wang R, Ding Q, Wang T, Xie B, Wei L, Zhong Z, Tian B. Cellular stress alters 3'UTR landscape through alternative polyadenylation and isoform-specific degradation. Nat Commun. 2018 06 11; 9(1):2268.
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van der Spek RA, van Rheenen W, Pulit SL, Kenna KP, Ticozzi N, Kooyman M, Mclaughlin RL, Moisse M, van Eijk KR, van Vugt JJFA, Iacoangeli A, Andersen P, Nazli Basak A, Blair I, de Carvalho M, Chio A, Corcia P, Couratier P, Drory VE, Glass JD, Hardiman O, Mora JS, Morrison KE, Mitne-Neto M, Robberecht W, Shaw PJ, Panad?s MP, van Damme P, Silani V, Gotkine M, Weber M, van Es MA, Landers JE, Al-Chalabi A, van den Berg LH, Veldink JH. Reconsidering the causality of TIA1 mutations in ALS. Amyotroph Lateral Scler Frontotemporal Degener. 2018 02; 19(1-2):1-3.
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Vanderweyde T, Apicco DJ, Youmans-Kidder K, Ash PEA, Cook C, Lummertz da Rocha E, Jansen-West K, Frame AA, Citro A, Leszyk JD, Ivanov P, Abisambra JF, Steffen M, Li H, Petrucelli L, Wolozin B. Interaction of tau with the RNA-Binding Protein TIA1 Regulates tau Pathophysiology and Toxicity. Cell Rep. 2016 05 17; 15(7):1455-1466.