"Poly(A)-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins that bind to the 3' polyadenylated region of MRNA. When complexed with RNA the proteins serve an array of functions such as stabilizing the 3' end of RNA, promoting poly(A) synthesis and stimulating mRNA translation.
| Descriptor ID |
D039102
|
| MeSH Number(s) |
D12.776.157.725.452 D12.776.664.962.452
|
| Concept/Terms |
Poly(A)-Binding Proteins- Poly(A)-Binding Proteins
- Poly(A)-Binding Protein
- Poly A-Binding Proteins
- Poly A Binding Proteins
- Poly(A)+ mRNA Binding Protein
- Poly A-Binding Protein
- Poly A Binding Protein
|
Below are MeSH descriptors whose meaning is more general than "Poly(A)-Binding Proteins".
Below are MeSH descriptors whose meaning is more specific than "Poly(A)-Binding Proteins".
This graph shows the total number of publications written about "Poly(A)-Binding Proteins" by people in this website by year, and whether "Poly(A)-Binding Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Poly(A)-Binding Proteins" by people in Profiles.
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Wu C, Roy B, He F, Yan K, Jacobson A. Poly(A)-Binding Protein Regulates the Efficiency of Translation Termination. Cell Rep. 2020 11 17; 33(7):108399.
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Zhang Y, Ling J, Yuan C, Dubruille R, Emery P. A role for Drosophila ATX2 in activation of PER translation and circadian behavior. Science. 2013 May 17; 340(6134):879-82.
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Fallini C, Zhang H, Su Y, Silani V, Singer RH, Rossoll W, Bassell GJ. The survival of motor neuron (SMN) protein interacts with the mRNA-binding protein HuD and regulates localization of poly(A) mRNA in primary motor neuron axons. J Neurosci. 2011 Mar 09; 31(10):3914-25.
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Amrani N, Ghosh S, Mangus DA, Jacobson A. Translation factors promote the formation of two states of the closed-loop mRNP. Nature. 2008 Jun 26; 453(7199):1276-80.
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Kim JH, Richter JD. RINGO/cdk1 and CPEB mediate poly(A) tail stabilization and translational regulation by ePAB. Genes Dev. 2007 Oct 15; 21(20):2571-9.
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Padmanabhan K, Richter JD. Regulated Pumilio-2 binding controls RINGO/Spy mRNA translation and CPEB activation. Genes Dev. 2006 Jan 15; 20(2):199-209.
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Cao Q, Richter JD. Dissolution of the maskin-eIF4E complex by cytoplasmic polyadenylation and poly(A)-binding protein controls cyclin B1 mRNA translation and oocyte maturation. EMBO J. 2002 Jul 15; 21(14):3852-62.