Heterogeneous-Nuclear Ribonucleoproteins
"Heterogeneous-Nuclear Ribonucleoproteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of ribonucleoproteins that were originally found as proteins bound to nascent RNA transcripts in the form of ribonucleoprotein particles. Although considered ribonucleoproteins they are primarily classified by their protein component. They are involved in a variety of processes such as packaging of RNA and RNA TRANSPORT within the nucleus. A subset of heterogeneous-nuclear ribonucleoproteins are involved in additional functions such as nucleocytoplasmic transport (ACTIVE TRANSPORT, CELL NUCLEUS) of RNA and mRNA stability in the CYTOPLASM.
| Descriptor ID |
D034441
|
| MeSH Number(s) |
D12.776.157.725.813.750 D12.776.664.962.813.750
|
| Concept/Terms |
Heterogeneous-Nuclear Ribonucleoproteins- Heterogeneous-Nuclear Ribonucleoproteins
- Heterogeneous Nuclear Ribonucleoproteins
- Ribonucleoproteins, Heterogeneous-Nuclear
- hnRNP
- Informofer
- Heterogeneous Nuclear Ribonucleoprotein
- Nuclear Ribonucleoprotein, Heterogeneous
- Ribonucleoprotein, Heterogeneous Nuclear
|
Below are MeSH descriptors whose meaning is more general than "Heterogeneous-Nuclear Ribonucleoproteins".
Below are MeSH descriptors whose meaning is more specific than "Heterogeneous-Nuclear Ribonucleoproteins".
This graph shows the total number of publications written about "Heterogeneous-Nuclear Ribonucleoproteins" by people in this website by year, and whether "Heterogeneous-Nuclear Ribonucleoproteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Heterogeneous-Nuclear Ribonucleoproteins" by people in Profiles.
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Jung S, Shah S, Han G, Richter JD. FMRP deficiency leads to multifactorial dysregulation of splicing and mislocalization of MBNL1 to the cytoplasm. PLoS Biol. 2023 Dec; 21(12):e3002417.
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Zhang S, Wei JS, Li SQ, Badgett TC, Song YK, Agarwal S, Coarfa C, Tolman C, Hurd L, Liao H, He J, Wen X, Liu Z, Thiele CJ, Westermann F, Asgharzadeh S, Seeger RC, Maris JM, Guidry Auvil JM, Smith MA, Kolaczyk ED, Shohet J, Khan J. MYCN controls an alternative RNA splicing program in high-risk metastatic neuroblastoma. Cancer Lett. 2016 Feb 28; 371(2):214-24.
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Carpenter S, Aiello D, Atianand MK, Ricci EP, Gandhi P, Hall LL, Byron M, Monks B, Henry-Bezy M, Lawrence JB, O'Neill LA, Moore MJ, Caffrey DR, Fitzgerald KA. A long noncoding RNA mediates both activation and repression of immune response genes. Science. 2013 Aug 16; 341(6147):789-92.
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Broderick J, Wang J, Andreadis A. Heterogeneous nuclear ribonucleoprotein E2 binds to tau exon 10 and moderately activates its splicing. Gene. 2004 Apr 28; 331:107-14.
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Ruskin B, Zamore PD, Green MR. A factor, U2AF, is required for U2 snRNP binding and splicing complex assembly. Cell. 1988 Jan 29; 52(2):207-19.