Ribonucleoprotein, U1 Small Nuclear
"Ribonucleoprotein, U1 Small Nuclear" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U1 snRNP along with other small nuclear ribonucleoproteins (U2, U4-U6, and U5) assemble into SPLICEOSOMES that remove introns from pre-mRNA by splicing. The U1 snRNA forms base pairs with conserved sequence motifs at the 5'-splice site and recognizes both the 5'- and 3'-splice sites and may have a fundamental role in aligning the two sites for the splicing reaction.
| Descriptor ID |
D017412
|
| MeSH Number(s) |
D12.776.157.725.500.875.600 D12.776.157.725.829.313 D12.776.664.962.500.875.600 D12.776.664.962.829.313
|
| Concept/Terms |
Ribonucleoprotein, U1 Small Nuclear- Ribonucleoprotein, U1 Small Nuclear
- U1 Small Nuclear Ribonucleoproteins
- Ribonucleoproteins, Small, U1
- Small Nuclear Ribonucleoproteins, U1
- U1 snRNP
|
Below are MeSH descriptors whose meaning is more general than "Ribonucleoprotein, U1 Small Nuclear".
Below are MeSH descriptors whose meaning is more specific than "Ribonucleoprotein, U1 Small Nuclear".
This graph shows the total number of publications written about "Ribonucleoprotein, U1 Small Nuclear" by people in this website by year, and whether "Ribonucleoprotein, U1 Small Nuclear" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 2 | 3 |
| 1998 | 1 | 1 | 2 |
| 2004 | 1 | 1 | 2 |
| 2006 | 1 | 1 | 2 |
| 2011 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Ribonucleoprotein, U1 Small Nuclear" by people in Profiles.
-
Misra A, Ou J, Zhu LJ, Green MR. Global Promotion of Alternative Internal Exon Usage by mRNA 3' End Formation Factors. Mol Cell. 2015 Jun 04; 58(5):819-31.
-
Hoskins AA, Friedman LJ, Gallagher SS, Crawford DJ, Anderson EG, Wombacher R, Ramirez N, Cornish VW, Gelles J, Moore MJ. Ordered and dynamic assembly of single spliceosomes. Science. 2011 Mar 11; 331(6022):1289-95.
-
Siebrasse JP, Gr?nwald D, Kubitscheck U. Single-molecule tracking in eukaryotic cell nuclei. Anal Bioanal Chem. 2007 Jan; 387(1):41-4.
-
Gr?nwald D, Spottke B, Buschmann V, Kubitscheck U. Intranuclear binding kinetics and mobility of single native U1 snRNP particles in living cells. Mol Biol Cell. 2006 Dec; 17(12):5017-27.
-
Du H, Tardiff DF, Moore MJ, Rosbash M. Effects of the U1C L13 mutation and temperature regulation of yeast commitment complex formation. Proc Natl Acad Sci U S A. 2004 Oct 12; 101(41):14841-6.
-
Imbalzano AN, Xiao H. Functional properties of ATP-dependent chromatin remodeling enzymes. Adv Protein Chem. 2004; 67:157-79.
-
Imbalzano AN. SWI/SNF complexes and facilitation of TATA binding protein:nucleosome interactions. Methods. 1998 Aug; 15(4):303-14.
-
Imbalzano AN. Energy-dependent chromatin remodelers: complex complexes and their components. Crit Rev Eukaryot Gene Expr. 1998; 8(3-4):225-55.
-
Imbalzano AN, Schnitzler GR, Kingston RE. Nucleosome disruption by human SWI/SNF is maintained in the absence of continued ATP hydrolysis. J Biol Chem. 1996 Aug 23; 271(34):20726-33.
-
Brown SA, Imbalzano AN, Kingston RE. Activator-dependent regulation of transcriptional pausing on nucleosomal templates. Genes Dev. 1996 Jun 15; 10(12):1479-90.