RNA Splicing

"RNA Splicing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The ultimate exclusion of nonsense sequences or intervening sequences (introns) before the final RNA transcript is sent to the cytoplasm.

Descriptor ID	D012326
MeSH Number(s)	G02.111.760.700 G03.839.700 G05.308.700.700
Concept/Terms	RNA Splicing RNA Splicing Splicing, RNA RNA Splicings Splicings, RNA RNA, Messenger, Splicing RNA, Messenger, Splicing

Below are MeSH descriptors whose meaning is more general than "RNA Splicing".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
RNA Processing, Post-Transcriptional [G02.111.760]
RNA Splicing [G02.111.760.700]
Metabolism [G03]
RNA Processing, Post-Transcriptional [G03.839]
RNA Splicing [G03.839.700]
Genetic Phenomena [G05]
Gene Expression Regulation [G05.308]
RNA Processing, Post-Transcriptional [G05.308.700]
RNA Splicing [G05.308.700.700]

Below are MeSH descriptors whose meaning is related to "RNA Splicing".

Below are MeSH descriptors whose meaning is more specific than "RNA Splicing".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "RNA Splicing" by people in this website by year, and whether "RNA Splicing" was a major or minor topic of these publications.

Bar chart showing 108 publications over 28 distinct years, with a maximum of 11 publications in 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	1	1
1997	1	0	1
1999	3	0	3
2000	2	2	4
2001	0	1	1
2002	3	1	4
2003	3	2	5
2004	3	1	4
2005	1	1	2
2006	1	3	4
2007	4	1	5
2008	2	4	6
2009	2	0	2
2010	0	5	5
2011	2	3	5
2012	1	3	4
2013	1	3	4
2014	4	3	7
2015	2	2	4
2016	1	1	2
2017	3	2	5
2018	4	7	11
2019	3	2	5
2020	1	2	3
2021	0	4	4
2022	2	1	3
2023	1	1	2
2025	2	0	2

Below are the most recent publications written about "RNA Splicing" by people in Profiles.

Jung S, Richter JD. Trinucleotide repeat expansion and RNA dysregulation in fragile X syndrome: emerging therapeutic approaches. RNA. 2025 Feb 19; 31(3):307-313.

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Zhang B, Orning P, Lehman JW, Dinis A, Torres-Ulloa L, Elling R, Kelliher MA, Bertin J, Proulx MK, Goguen JD, Ryan L, Kandasamy RK, Espevik T, Pai AA, Fitzgerald KA, Lien E. Raver1 links Ripk1 RNA splicing to caspase-8-mediated pyroptotic cell death, inflammation, and pathogen resistance. Proc Natl Acad Sci U S A. 2025 Feb 18; 122(7):e2420802122.

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Jung S, Shah S, Han G, Richter JD. FMRP deficiency leads to multifactorial dysregulation of splicing and mislocalization of MBNL1 to the cytoplasm. PLoS Biol. 2023 Dec; 21(12):e3002417.

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Schultz A, Cheng SY, Kirchner E, Costello S, Miettinen H, Chaverra M, King C, George L, Zhao X, Narasimhan J, Weetall M, Slaugenhaupt S, Morini E, Punzo C, Lefcort F. Reduction of retinal ganglion cell death in mouse models of familial dysautonomia using AAV-mediated gene therapy and splicing modulators. Sci Rep. 2023 10 30; 13(1):18600.

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Vierbuchen T, Agarwal S, Johnson JL, Galia L, Lei X, Stein K, Olagnier D, Gaede KI, Herzmann C, Holm CK, Heine H, Pai A, O'Hara Hall A, Hoebe K, Fitzgerald KA. The lncRNA LUCAT1 is elevated in inflammatory disease and restrains inflammation by regulating the splicing and stability of NR4A2. Proc Natl Acad Sci U S A. 2023 01 03; 120(1):e2213715120.

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Yang X, Triboulet R, Liu Q, Sendinc E, Gregory RI. Exon junction complex shapes the m6A epitranscriptome. Nat Commun. 2022 12 23; 13(1):7904.

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Aartsma-Rus A, Garanto A, van Roon-Mom W, McConnell EM, Suslovitch V, Yan WX, Watts JK, Yu TW. Consensus Guidelines for the Design and In Vitro Preclinical Efficacy Testing N-of-1 Exon Skipping Antisense Oligonucleotides. Nucleic Acid Ther. 2023 01; 33(1):17-25.

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Tahtouh T, Durieu E, Villiers B, Bruy?re C, Nguyen TL, Fant X, Ahn KH, Khurana L, Deau E, Lindberg MF, S?v?re E, Miege F, Roche D, Limanton E, L'Helgoual'ch JM, Burgy G, Guiheneuf S, Herault Y, Kendall DA, Carreaux F, Bazureau JP, Meijer L. Structure-Activity Relationship in the Leucettine Family of Kinase Inhibitors. J Med Chem. 2022 01 27; 65(2):1396-1417.

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Makeyeva YV, Shirayama M, Mello CC. Cues from mRNA splicing prevent default Argonaute silencing in C.?elegans. Dev Cell. 2021 09 27; 56(18):2636-2648.e4.

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Burns W, Bird LM, Heron D, Keren B, Ramachandra D, Thiffault I, Del Viso F, Amudhavalli S, Engleman K, Parenti I, Kaiser FJ, Wierzba J, Riedhammer KM, Liptay S, Zadeh N, Porrmann J, Fischer A, G??wein S, McLaughlin HM, Telegrafi A, Langley KG, Steet R, Louie RJ, Lyons MJ. Syndromic neurodevelopmental disorder associated with de novo variants in DDX23. Am J Med Genet A. 2021 10; 185(10):2863-2872.

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