RNA Stability

"RNA Stability" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The extent to which an RNA molecule retains its structural integrity and resists degradation by RNASE, and base-catalyzed HYDROLYSIS, under changing in vivo or in vitro conditions.

Descriptor ID	D020871
MeSH Number(s)	G02.111.780
Concept/Terms	RNA Stability RNA Stability Stability, RNA mRNA Stability mRNA Stability Stability, mRNA mRNA Degradation mRNA Degradation Degradation, mRNA mRNA Transcript Degradation Degradation, mRNA Transcript Transcript Degradation, mRNA RNA Degradation RNA Degradation Degradation, RNA RNA Instability RNA Instability Instability, RNA mRNA Decay mRNA Decay Decay, mRNA mRNA Instability mRNA Instability Instability, mRNA RNA Decay RNA Decay Decay, RNA

Below are MeSH descriptors whose meaning is more general than "RNA Stability".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
RNA Stability [G02.111.780]

Below are MeSH descriptors whose meaning is related to "RNA Stability".

Below are MeSH descriptors whose meaning is more specific than "RNA Stability".

RNA Stability
Nonsense Mediated mRNA Decay

publications

Timeline | Most Recent

This graph shows the total number of publications written about "RNA Stability" by people in this website by year, and whether "RNA Stability" was a major or minor topic of these publications.

Bar chart showing 78 publications over 23 distinct years, with a maximum of 7 publications in 2007

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	1	2	3
2002	0	1	1
2003	1	4	5
2004	0	2	2
2005	1	0	1
2006	0	1	1
2007	1	6	7
2008	3	2	5
2009	1	4	5
2010	4	1	5
2011	1	4	5
2012	2	4	6
2013	4	2	6
2014	2	1	3
2015	0	4	4
2016	0	2	2
2017	1	2	3
2018	0	2	2
2019	1	1	2
2020	0	2	2
2022	0	4	4
2023	1	0	1
2024	3	0	3

Below are the most recent publications written about "RNA Stability" by people in Profiles.

O'Reilly ME, Ho S, Coronel J, Zhu L, Liu W, Xue C, Kim E, Cynn E, Matias CV, Soni RK, Wang C, Ionita-Laza I, Bauer RC, Ross L, Zhang Y, Corvera S, Fried SK, Reilly MP. linc-ADAIN, a human adipose lincRNA, regulates adipogenesis by modulating KLF5 and IL-8 mRNA stability. Cell Rep. 2024 05 28; 43(5):114240.

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Mercier BC, Labaronne E, Cluet D, Guiguettaz L, Fontrodona N, Bicknell A, Corbin A, Wencker M, Aube F, Modolo L, Jouravleva K, Auboeuf D, Moore MJ, Ricci EP. Translation-dependent and -independent mRNA decay occur through mutually exclusive pathways defined by ribosome density during T cell activation. Genome Res. 2024 04 25; 34(3):394-409.

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Bicknell AA, Reid DW, Licata MC, Jones AK, Cheng YM, Li M, Hsiao CJ, Pepin CS, Metkar M, Levdansky Y, Fritz BR, Andrianova EA, Jain R, Valkov E, K?hrer C, Moore MJ. Attenuating ribosome load improves protein output from mRNA by limiting translation-dependent mRNA decay. Cell Rep. 2024 04 23; 43(4):114098.

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Bryll AR, Peterson CL. The circular logic of mRNA homeostasis. Transcription. 2023 11; 14(1-2):18-26.

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Vierbuchen T, Agarwal S, Johnson JL, Galia L, Lei X, Stein K, Olagnier D, Gaede KI, Herzmann C, Holm CK, Heine H, Pai A, O'Hara Hall A, Hoebe K, Fitzgerald KA. The lncRNA LUCAT1 is elevated in inflammatory disease and restrains inflammation by regulating the splicing and stability of NR4A2. Proc Natl Acad Sci U S A. 2023 01 03; 120(1):e2213715120.

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Yang X, Triboulet R, Liu Q, Sendinc E, Gregory RI. Exon junction complex shapes the m6A epitranscriptome. Nat Commun. 2022 12 23; 13(1):7904.

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He F, Jacobson A. Eukaryotic mRNA decapping factors: molecular mechanisms and activity. FEBS J. 2023 11; 290(21):5057-5085.

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He F, Wu C, Jacobson A. Dcp2 C-terminal cis-binding elements control selective targeting of the decapping enzyme by forming distinct decapping complexes. Elife. 2022 05 23; 11.

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Shu H, Donnard E, Liu B, Jung S, Wang R, Richter JD. FMRP links optimal codons to mRNA stability in neurons. Proc Natl Acad Sci U S A. 2020 12 01; 117(48):30400-30411.

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Carbone CE, Demo G, Madireddy R, Svidritskiy E, Korostelev AA. ArfB can displace mRNA to rescue stalled ribosomes. Nat Commun. 2020 11 03; 11(1):5552.

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