RNA Processing, Post-Transcriptional

"RNA Processing, Post-Transcriptional" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Post-transcriptional biological modification of messenger, transfer, or ribosomal RNAs or their precursors. It includes cleavage, methylation, thiolation, isopentenylation, pseudouridine formation, conformational changes, and association with ribosomal protein.

Descriptor ID	D012323
MeSH Number(s)	G02.111.760 G03.839 G05.308.700
Concept/Terms	RNA Processing, Post-Transcriptional RNA Processing, Post-Transcriptional Post-Transcriptional RNA Processing Post Transcriptional RNA Processing RNA Processing, Posttranscriptional Posttranscriptional RNA Processing Processing, Posttranscriptional RNA Post-Transcriptional RNA Modification Modification, Post-Transcriptional RNA Modifications, Post-Transcriptional RNA Post Transcriptional RNA Modification Post-Transcriptional RNA Modifications RNA Modification, Post-Transcriptional RNA Modifications, Post-Transcriptional RNA Processing, Post Transcriptional

Below are MeSH descriptors whose meaning is more general than "RNA Processing, Post-Transcriptional".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
RNA Processing, Post-Transcriptional [G02.111.760]
Metabolism [G03]
RNA Processing, Post-Transcriptional [G03.839]
Genetic Phenomena [G05]
Gene Expression Regulation [G05.308]
RNA Processing, Post-Transcriptional [G05.308.700]

Below are MeSH descriptors whose meaning is related to "RNA Processing, Post-Transcriptional".

Below are MeSH descriptors whose meaning is more specific than "RNA Processing, Post-Transcriptional".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "RNA Processing, Post-Transcriptional" by people in this website by year, and whether "RNA Processing, Post-Transcriptional" was a major or minor topic of these publications.

Bar chart showing 79 publications over 27 distinct years, with a maximum of 6 publications in 2011 and 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	1	2	3
2000	0	3	3
2001	2	3	5
2002	1	2	3
2003	1	1	2
2004	0	1	1
2005	1	2	3
2006	2	0	2
2007	1	1	2
2008	1	1	2
2009	2	0	2
2010	2	2	4
2011	5	1	6
2012	3	2	5
2013	0	3	3
2014	1	3	4
2015	3	2	5
2016	1	0	1
2017	1	1	2
2018	5	1	6
2019	1	1	2
2020	2	1	3
2021	0	5	5
2022	1	1	2
2024	0	1	1
2025	0	1	1
2026	1	0	1

Below are the most recent publications written about "RNA Processing, Post-Transcriptional" by people in Profiles.

Galambos NS, Crocker OJ, Schneider BK, Allerton KS, Gross KE, Schneider AE, Lynch J, Yukselen O, Kucukural A, Conine CC. tRNA-derived RNA processing in sperm transmits non-genetically inherited phenotypes to offspring in C. elegans. Nat Commun. 2026 Mar 15; 17(1).

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Zbihley ONP, Johnson K, Frietze LR, Zhang W, Foo M, Tran HAV, Chevrier N, Pan T. Mammalian Queuosine tRNA Modification Impacts Translation to Enhance Cell Proliferation and MHC-II Expression. J Mol Biol. 2025 Aug 15; 437(16):169188.

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Werren EA, LaForce GR, Srivastava A, Perillo DR, Li S, Johnson K, Baris S, Berger B, Regan SL, Pfennig CD, de Munnik S, Pfundt R, Hebbar M, Jimenez-Heredia R, Karakoc-Aydiner E, Ozen A, Dmytrus J, Krolo A, Corning K, Prijoles EJ, Louie RJ, Lebel RR, Le TL, Amiel J, Gordon CT, Boztug K, Girisha KM, Shukla A, Bielas SL, Schaffer AE. TREX tetramer disruption alters RNA processing necessary for corticogenesis in THOC6 Intellectual Disability Syndrome. Nat Commun. 2024 Feb 22; 15(1):1640.

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Orellana EA, Siegal E, Gregory RI. tRNA dysregulation and disease. Nat Rev Genet. 2022 11; 23(11):651-664.

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Estevez M, Li R, Paul B, Daneshvar K, Mullen AC, Romerio F, Addepalli B. Identification and mapping of post-transcriptional modifications on the HIV-1 antisense transcript Ast in human cells. RNA. 2022 05; 28(5):697-710.

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Wu T, Nance J, Chu F, Fazzio TG. Characterization of R-Loop-Interacting Proteins in Embryonic Stem Cells Reveals Roles in rRNA Processing and Gene Expression. Mol Cell Proteomics. 2021; 20:100142.

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Orellana EA, Liu Q, Yankova E, Pirouz M, De Braekeleer E, Zhang W, Lim J, Aspris D, Sendinc E, Garyfallos DA, Gu M, Ali R, Gutierrez A, Mikutis S, Bernardes GJL, Fischer ES, Bradley A, Vassiliou GS, Slack FJ, Tzelepis K, Gregory RI. METTL1-mediated m7G modification of Arg-TCT tRNA drives oncogenic transformation. Mol Cell. 2021 08 19; 81(16):3323-3338.e14.

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Xiong X, Hou L, Park YP, Molinie B, Gregory RI, Kellis M. Genetic drivers of m6A methylation in human brain, lung, heart and muscle. Nat Genet. 2021 08; 53(8):1156-1165.

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Kovalak C, Donovan S, Bicknell AA, Metkar M, Moore MJ. Deep sequencing of pre-translational mRNPs reveals hidden flux through evolutionarily conserved alternative splicing nonsense-mediated decay pathways. Genome Biol. 2021 05 03; 22(1):132.

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Pirie E, Oh CK, Zhang X, Han X, Cieplak P, Scott HR, Deal AK, Ghatak S, Martinez FJ, Yeo GW, Yates JR, Nakamura T, Lipton SA. S-nitrosylated TDP-43 triggers aggregation, cell-to-cell spread, and neurotoxicity in hiPSCs and in vivo models of ALS/FTD. Proc Natl Acad Sci U S A. 2021 03 16; 118(11).

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