RNA Cleavage

"RNA Cleavage" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A reaction that severs one of the sugar-phosphate linkages of the phosphodiester backbone of RNA. It is catalyzed enzymatically, chemically, or by radiation. Cleavage may be exonucleolytic, or endonucleolytic.

Descriptor ID	D059367
MeSH Number(s)	G02.111.740 G05.755
Concept/Terms	RNA Cleavage RNA Cleavage Cleavage, RNA Cleavages, RNA RNA Cleavages

Below are MeSH descriptors whose meaning is more general than "RNA Cleavage".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
RNA Cleavage [G02.111.740]
Genetic Phenomena [G05]
RNA Cleavage [G05.755]

Below are MeSH descriptors whose meaning is related to "RNA Cleavage".

Below are MeSH descriptors whose meaning is more specific than "RNA Cleavage".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "RNA Cleavage" by people in this website by year, and whether "RNA Cleavage" was a major or minor topic of these publications.

Bar chart showing 8 publications over 6 distinct years, with a maximum of 2 publications in 2011 and 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2011	1	1	2
2015	1	1	2
2016	1	0	1
2022	1	0	1
2024	0	1	1
2025	1	0	1

Below are the most recent publications written about "RNA Cleavage" by people in Profiles.

Kraus C, Wang J, Zheng H, Broderick J, Ajaykumar N, Zamani M, Yang M, Cecchini K, Liang SQ, Kolumba O, Chase K, Lee J, Xue W, Sontheimer EJ, Gainetdinov I. Absolute quantification of mammalian microRNAs for therapeutic RNA cleavage and detargeting. RNA. 2025 Jul 16; 31(8):1081-1090.

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Loveland AB, Koh CS, Ganesan R, Jacobson A, Korostelev AA. Structural mechanism of angiogenin activation by the ribosome. Nature. 2024 Jun; 630(8017):769-776.

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Arif A, Bailey S, Izumi N, Anzelon TA, Ozata DM, Andersson C, Gainetdinov I, MacRae IJ, Tomari Y, Zamore PD. GTSF1 accelerates target RNA cleavage by PIWI-clade Argonaute proteins. Nature. 2022 08; 608(7923):618-625.

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Wang R, Nambiar R, Zheng D, Tian B. PolyA_DB 3 catalogs cleavage and polyadenylation sites identified by deep sequencing in multiple genomes. Nucleic Acids Res. 2018 01 04; 46(D1):D315-D319.

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Pirouz M, Du P, Munaf? M, Gregory RI. Dis3l2-Mediated Decay Is a Quality Control Pathway for Noncoding RNAs. Cell Rep. 2016 08 16; 16(7):1861-73.

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Wang W, Han BW, Tipping C, Ge DT, Zhang Z, Weng Z, Zamore PD. Slicing and Binding by Ago3 or Aub Trigger Piwi-Bound piRNA Production by Distinct Mechanisms. Mol Cell. 2015 Sep 03; 59(5):819-30.

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Han BW, Wang W, Li C, Weng Z, Zamore PD. Noncoding RNA. piRNA-guided transposon cleavage initiates Zucchini-dependent, phased piRNA production. Science. 2015 May 15; 348(6236):817-21.

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Zhang Z, Xu J, Koppetsch BS, Wang J, Tipping C, Ma S, Weng Z, Theurkauf WE, Zamore PD. Heterotypic piRNA Ping-Pong requires qin, a protein with both E3 ligase and Tudor domains. Mol Cell. 2011 Nov 18; 44(4):572-84.

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Korennykh AV, Korostelev AA, Egea PF, Finer-Moore J, Stroud RM, Zhang C, Shokat KM, Walter P. Structural and functional basis for RNA cleavage by Ire1. BMC Biol. 2011 Jul 06; 9:47.

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