DNA Methylation

"DNA Methylation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Addition of methyl groups to DNA. DNA methyltransferases (DNA methylases) perform this reaction using S-ADENOSYLMETHIONINE as the methyl group donor.

Descriptor ID	D019175
MeSH Number(s)	G02.111.035.538.161 G02.111.218 G03.059.538.161 G05.206
Concept/Terms	DNA Methylation DNA Methylation DNA Methylations Methylation, DNA Methylations, DNA

Below are MeSH descriptors whose meaning is more general than "DNA Methylation".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Alkylation [G02.111.035]
Methylation [G02.111.035.538]
DNA Methylation [G02.111.035.538.161]
DNA Methylation [G02.111.218]
Metabolism [G03]
Alkylation [G03.059]
Methylation [G03.059.538]
DNA Methylation [G03.059.538.161]
Genetic Phenomena [G05]
DNA Methylation [G05.206]

Below are MeSH descriptors whose meaning is related to "DNA Methylation".

Below are MeSH descriptors whose meaning is more specific than "DNA Methylation".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "DNA Methylation" by people in this website by year, and whether "DNA Methylation" was a major or minor topic of these publications.

Bar chart showing 233 publications over 28 distinct years, with a maximum of 20 publications in 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	2	2
1999	1	1	2
2000	1	1	2
2001	2	2	4
2002	3	4	7
2003	2	5	7
2004	1	0	1
2005	3	1	4
2006	2	3	5
2007	1	5	6
2008	2	2	4
2009	3	3	6
2010	5	7	12
2011	10	1	11
2012	3	7	10
2013	7	7	14
2014	6	11	17
2015	8	10	18
2016	8	7	15
2017	5	4	9
2018	5	9	14
2019	8	6	14
2020	5	15	20
2021	4	7	11
2022	2	2	4
2023	1	3	4
2024	3	2	5
2025	1	4	5

Below are the most recent publications written about "DNA Methylation" by people in Profiles.

Jung S, Richter JD. Trinucleotide repeat expansion and RNA dysregulation in fragile X syndrome: emerging therapeutic approaches. RNA. 2025 Feb 19; 31(3):307-313.

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Nguyen LHD, Nguyen THH, Le VH, Bui VQ, Nguyen LH, Pham NH, Phan TH, Nguyen HT, Tran VS, Bui CV, Vo VK, Nguyen PTN, Dang HHP, Pham VD, Cao VT, Phan NM, Tieu BL, Nguyen GTH, Vo DH, Tran TH, Nguyen TD, Nguyen VTC, Nguyen TH, Tran VU, Le MP, Tran TMT, Nguyen Nguyen M, Van TTV, Nguyen AN, Nguyen TT, Doan NNT, Nguyen HT, Doan PL, Huynh LAK, Nguyen TA, Nguyen HTP, Lu YT, Cao CTT, Nguyen VT, Le Quyen Le T, Luong TL, Doan TKP, Dao TT, Phan CD, Nguyen TX, Pham NT, Nguyen BT, Pham TTT, Le HL, Truong CT, Jasmine TX, Le MC, Phan VB, Truong QB, Tran THL, Huynh MT, Tran TQ, Nguyen ST, Tran V, Tran VK, Nguyen Nguyen H, Nguyen DS, Van Phan T, Do TT, Truong DK, Tang HS, Giang H, Nguyen HN, Phan MD, Tran LS. Prospective validation study: a non-invasive circulating tumor DNA-based assay for simultaneous early detection of multiple cancers in asymptomatic adults. BMC Med. 2025 Feb 14; 23(1):90.

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Nguyen THH, Vu GH, Nguyen TT, Nguyen TA, Tran VU, Vu LT, Nguyen GTH, Nguyen ND, Tran TH, Nguyen VTC, Nguyen TD, Nguyen TH, Vo DH, Van TTV, Do TT, Le MP, Huynh LAK, Nguyen DS, Tang HS, Nguyen HN, Phan MD, Giang H, Tu LN, Tran LS. Combination of Hotspot Mutations With Methylation and Fragmentomic Profiles to Enhance Multi-Cancer Early Detection. Cancer Med. 2025 Jan; 14(1):e70575.

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van Zundert B, Montecino M. Epigenetics in Learning and Memory. Subcell Biochem. 2025; 108:51-71.

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van Zundert B, Montecino M. Epigenetics in Neurodegenerative Diseases. Subcell Biochem. 2025; 108:73-109.

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Katayama M, Nomura K, Mudry JM, Chibalin AV, Krook A, Zierath JR. Exercise-induced methylation of the Serhl2 promoter and implication for lipid metabolism in rat skeletal muscle. Mol Metab. 2025 Feb; 92:102081.

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Wu MJ, Kondo H, Kammula AV, Shi L, Xiao Y, Dhiab S, Xu Q, Slater CJ, Avila OI, Merritt J, Kato H, Kattel P, Sussman J, Gritti I, Eccleston J, Sun Y, Cho HM, Olander K, Katsuda T, Shi DD, Savani MR, Smith BC, Cleary JM, Mostoslavsky R, Vijay V, Kitagawa Y, Wakimoto H, Jenkins RW, Yates KB, Paik J, Tassinari A, Saatcioglu DH, Tron AE, Haas W, Cahill D, McBrayer SK, Manguso RT, Bardeesy N. Mutant IDH1 inhibition induces dsDNA sensing to activate tumor immunity. Science. 2024 Jul 12; 385(6705):eadl6173.

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Campbell M, Barton IS, Roop RM, Chien P. Comparison of CcrM-dependent methylation in Caulobacter crescentus and Brucella abortus by nanopore sequencing. J Bacteriol. 2024 06 20; 206(6):e0008324.

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Forrester SN, Baek J, Hou L, Roger V, Kiefe CI. A Comparison of 5 Measures of Accelerated Biological Aging and Their Association With Incident Cardiovascular Disease: The CARDIA Study. J Am Heart Assoc. 2024 Apr 16; 13(8):e032847.

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Scelfo A, Barra V, Abdennur N, Spracklin G, Busato F, Salinas-Luypaert C, Bonaiti E, Velasco G, Bonhomme F, Chipont A, Tijhuis AE, Spierings DCJ, Gu?rin C, Arimondo P, Francastel C, Foijer F, Tost J, Mirny L, Fachinetti D. Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization. J Cell Biol. 2024 04 01; 223(4).

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