Below are the most recent publications written about "Proteolysis" by people in Profiles.
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Nachum GS, Boucher JI, Flynn JM, Quansah P, Nachum S, Bolon DNA. Mutational scan of self-cleavage by HIV-1 protease provides new views of a conformationally dynamic mechanism. J Virol. 2026 Apr 21; 100(4):e0222925.
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Karunakaran AC, Bakshi M, Rajendrakumar AM, Wilson-Welder JH, Aroian RV, Schwarz EM, Homan EJ, Ostroff GR, Beshah E, Miramontes E, Papadopoulos MD, Bowdridge SA, Zarlenga DS, Zhu X, Tuo W. Catalytically Active Recombinant Cysteine Proteases of Haemonchus contortus: Their Ability to Degrade Host Blood Proteins and Modulate Coagulation. Int J Mol Sci. 2025 Dec 16; 26(24).
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Chen Y, Guo Z, Xiao H, Cai W, Peng Z, Wang K, Xiao W, Huang J. Programmable DNA Nanospheres for Photothermal-Controlled Intracellular Protein Degradation. Angew Chem Int Ed Engl. 2026 01 09; 65(2):e17452.
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Skorupka KA, Matsuoka K, Hassan B, Ghirlando R, Balachandran V, Chen TH, Walters KJ, Schiffer CA, Wolf M, Iwatani Y, Matsuo H. HIV-1 vif mediates ubiquitination of the proximal protomer in the APOBEC3H dimer to induce degradation. Nat Commun. 2025 Jul 01; 16(1):5879.
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Yigit K, Chien P. Lon-dependent proteolysis in oxidative stress responses. J Bacteriol. 2025 Jul 24; 207(7):e0000525.
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Du Y, Yang Y, Nguyen SN, Kaltashov IA. The Role of Long-Range Non-Specific Electrostatic Interactions in Inhibiting the Pre-Fusion Proteolytic Processing of the SARS-CoV-2 S Glycoprotein by Heparin. Biomolecules. 2025 05 28; 15(6).
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Hong L, Ye T, Wang TZ, Srijay D, Liu H, Zhao L, Watson R, Vincoff S, Chen T, Kholina K, Goel S, DeLisa MP, Chatterjee P. Programmable protein stabilization with language model-derived peptide guides. Nat Commun. 2025 Apr 15; 16(1):3555.
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Sin YY, Giblin A, Judina A, Rujirachaivej P, Corral LG, Glennon E, Tai ZX, Feng T, Torres E, Zorn A, Gorelik J, Kyurkchieva E, Yenchitsomanus PT, Swindlehurst C, Chan K, Stirling D, Baillie GS. Targeted protein degradation of PDE4 shortforms by a novel proteolysis targeting chimera. FEBS J. 2025 Jul; 292(13):3360-3377.
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Flynn JM, Joyce ME, Bolon DNA. Dominant negative mutations in yeast Hsp90 indicate triage decision mechanism targeting client proteins for degradation. Mol Biol Cell. 2025 Jan 01; 36(1):ar5.
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Yerramilli VS, Lin G, Reisinger JL, Hemmerlin RM, Lindberg SK, Plante K, Ross AH, Gericke A, Scarlata S. The scaffolding protein IQGAP1 enhances EGFR signaling by promoting oligomerization and preventing degradation. J Biol Chem. 2024 11; 300(11):107844.