Metabolic Clearance Rate

"Metabolic Clearance Rate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Volume of biological fluid completely cleared of drug metabolites as measured in unit time. Elimination occurs as a result of metabolic processes in the kidney, liver, saliva, sweat, intestine, heart, brain, or other site.

Descriptor ID	D008657
MeSH Number(s)	E01.370.225.843 E05.200.843 G03.490 G07.690.595 G07.690.725.513
Concept/Terms	Metabolic Clearance Rate Metabolic Clearance Rate Clearance Rate, Metabolic Clearance Rates, Metabolic Metabolic Clearance Rates Rate, Metabolic Clearance Rates, Metabolic Clearance Total Body Clearance Rate Total Body Clearance Rate

Below are MeSH descriptors whose meaning is more general than "Metabolic Clearance Rate".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Diagnosis [E01]
Diagnostic Techniques and Procedures [E01.370]
Clinical Laboratory Techniques [E01.370.225]
Metabolic Clearance Rate [E01.370.225.843]
Investigative Techniques [E05]
Clinical Laboratory Techniques [E05.200]
Metabolic Clearance Rate [E05.200.843]
Biological Sciences [G]
Metabolism [G03]
Metabolic Clearance Rate [G03.490]
Physiological Phenomena [G07]
Pharmacological and Toxicological Phenomena [G07.690]
Metabolic Clearance Rate [G07.690.595]
Pharmacokinetics [G07.690.725]
Metabolic Clearance Rate [G07.690.725.513]

Below are MeSH descriptors whose meaning is related to "Metabolic Clearance Rate".

Below are MeSH descriptors whose meaning is more specific than "Metabolic Clearance Rate".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Metabolic Clearance Rate" by people in this website by year, and whether "Metabolic Clearance Rate" was a major or minor topic of these publications.

Bar chart showing 41 publications over 19 distinct years, with a maximum of 5 publications in 2003

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
1996	2	2
1999	1	1
2000	2	2
2002	2	2
2003	5	5
2004	4	4
2005	4	4
2006	2	2
2007	4	4
2009	2	2
2010	2	2
2011	1	1
2012	3	3
2013	1	1
2015	2	2
2017	1	1
2018	1	1
2020	1	1
2022	1	1

Below are the most recent publications written about "Metabolic Clearance Rate" by people in Profiles.

Mo Y, Shcherbakova N, Inman KL, Li WK, Kovalenko K, Rosenberg J, Orsini J, Truong J. Evaluation of Individualized Cefepime Dosing Strategy Using Population Pharmacokinetics. J Clin Pharmacol. 2022 03; 62(3):359-365.

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Luo MM, Usmani SZ, Mateos MV, Nahi H, Chari A, San-Miguel J, Touzeau C, Suzuki K, Kaiser M, Carson R, Heuck C, Qi M, Zhou H, Sun YN, Parasrampuria DA. Exposure-Response and Population Pharmacokinetic Analyses of a Novel Subcutaneous Formulation of Daratumumab Administered to Multiple Myeloma Patients. J Clin Pharmacol. 2021 05; 61(5):614-627.

View in: PubMed
Yan X, Clemens PL, Puchalski T, Lonial S, Lokhorst H, Voorhees PM, Usmani S, Richardson PG, Plesner T, Liu K, Orlowski RZ, Losic N, Jansson R, Ahmadi T, Lantz K, Ruixo JJP, Zhou H, Xu XS. Influence of Disease and Patient Characteristics on Daratumumab Exposure and Clinical Outcomes in Relapsed or Refractory Multiple Myeloma. Clin Pharmacokinet. 2018 04; 57(4):529-538.

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Landersdorfer CB, Findling RL, Frazier JA, Kafantaris V, Kirkpatrick CM. Lithium in Paediatric Patients with Bipolar Disorder: Implications for Selection of Dosage Regimens via Population Pharmacokinetics/Pharmacodynamics. Clin Pharmacokinet. 2017 01; 56(1):77-90.

View in: PubMed
Zazzeron L, Liu C, Franco W, Nakagawa A, Farinelli WA, Bloch DB, Anderson RR, Zapol WM. Pulmonary Phototherapy for Treating Carbon Monoxide Poisoning. Am J Respir Crit Care Med. 2015 Nov 15; 192(10):1191-9.

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Matsumoto K, Yamasaki T, Nakamura M, Ishikawa J, Ueno M, Nakanishi I, Sekita A, Ozawa Y, Kamada T, Aoki I, Yamada K. Brain contrasting ability of blood-brain-barrier-permeable nitroxyl contrast agents for magnetic resonance redox imaging. Magn Reson Med. 2016 09; 76(3):935-45.

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Jimeno A, Weiss GJ, Miller WH, Gettinger S, Eigl BJ, Chang AL, Dunbar J, Devens S, Faia K, Skliris G, Kutok J, Lewis KD, Tibes R, Sharfman WH, Ross RW, Rudin CM. Phase I study of the Hedgehog pathway inhibitor IPI-926 in adult patients with solid tumors. Clin Cancer Res. 2013 May 15; 19(10):2766-74.

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Lee EJ, Alonso LC, Stefanovski D, Strollo HC, Romano LC, Zou B, Singamsetty S, Yester KA, McGaffin KR, Garcia-Ocana A, O'Donnell CP. Time-dependent changes in glucose and insulin regulation during intermittent hypoxia and continuous hypoxia. Eur J Appl Physiol. 2013 Feb; 113(2):467-78.

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Le Gall JB, Milone MC, Waxman IM, Shaw LM, Harrison L, Duffy D, van de Ven C, Militano O, Geyer MB, Morris E, Bhatia M, Satwani P, George D, Garvin JH, Bradley MB, Schwartz J, Baxter-Lowe LA, Cairo MS. The pharmacokinetics and safety of twice daily i.v. BU during conditioning in pediatric allo-SCT recipients. Bone Marrow Transplant. 2013 Jan; 48(1):19-25.

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Smith BS, Yogaratnam D, Levasseur-Franklin KE, Forni A, Fong J. Introduction to drug pharmacokinetics in the critically ill patient. Chest. 2012 May; 141(5):1327-1336.

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