Biological Availability

"Biological Availability" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The extent to which the active ingredient of a drug dosage form becomes available at the site of drug action or in a biological medium believed to reflect accessibility to a site of action.

Descriptor ID	D001682
MeSH Number(s)	G03.787.151 G07.690.725.129
Concept/Terms	Biological Availability Biological Availability Availability, Biological Availabilities, Biological Biological Availabilities Biologic Availability Physiologic Availability Availability, Biologic Availabilities, Biologic Biologic Availabilities Bioavailability Bioavailabilities Availability, Physiologic Availabilities, Physiologic Physiologic Availabilities Availability Equivalency Availability Equivalency Availability Equivalencies Equivalencies, Availability Equivalency, Availability

Below are MeSH descriptors whose meaning is more general than "Biological Availability".

Biological Sciences [G]
Metabolism [G03]
Pharmacokinetics [G03.787]
Biological Availability [G03.787.151]
Physiological Phenomena [G07]
Pharmacological and Toxicological Phenomena [G07.690]
Pharmacokinetics [G07.690.725]
Biological Availability [G07.690.725.129]

Below are MeSH descriptors whose meaning is related to "Biological Availability".

Below are MeSH descriptors whose meaning is more specific than "Biological Availability".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Biological Availability" by people in this website by year, and whether "Biological Availability" was a major or minor topic of these publications.

Bar chart showing 165 publications over 23 distinct years, with a maximum of 20 publications in 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	0	1	1
2001	0	1	1
2002	0	3	3
2003	0	1	1
2004	0	1	1
2005	0	3	3
2009	0	5	5
2010	1	3	4
2011	0	2	2
2012	0	7	7
2013	0	13	13
2014	0	5	5
2015	0	12	12
2016	0	8	8
2017	1	6	7
2018	0	14	14
2019	1	19	20
2020	1	12	13
2021	0	14	14
2022	1	10	11
2023	0	4	4
2024	1	10	11
2025	0	5	5

Below are the most recent publications written about "Biological Availability" by people in Profiles.

Li C, Shang H, Hu X, Eggleston I, McClements DJ, Han B, White JC, Ma C, Xing B. Surface functionalized polystyrene nanoplastics impair nutrient assimilation from corn kernels (Zea mays L.) in a simulated human digestive tract. J Hazard Mater. 2025 Sep 15; 496:139436.

View in: PubMed
Liu F, Zhao B, Wang Q, Lei Z, McClements DJ, Wang S, Chen S. Potential application of quercetin as an anti-diabetic treatment: From molecular mechanism to delivery system design. Phytomedicine. 2025 Sep; 145:157036.

View in: PubMed
Li S, Luo M, Gao Z, Zhang Y, Demircan B, Yan W, McClements DJ. Effects of polyphenols on the functional properties, digestibility, and iron bioavailability of potato protein-iron complexes. Food Chem. 2025 Oct 15; 489:144932.

View in: PubMed
Shadrack SM, Wang Y, Mi S, Lu R, Zhu Y, Tang Z, McClements DJ, Cao C, Xu X, Li W, Yuan B. Enhancing bioavailability and functionality of plant peptides and proteins: A review of novel strategies for food and pharmaceutical applications. Food Chem. 2025 Sep 01; 485:144440.

View in: PubMed
Grundy MM, Deglaire A, Le Feunteun S, Reboul E, Moughan PJ, Wilde PJ, McClements DJ, Marze S. Bioaccessibility and associated concepts: Terminology in the context of in vitro food digestion studies. Food Chem. 2025 Sep 01; 485:144424.

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Hu Q, Tang X, Long R, Pan X, Shi S, Liu J, Pan Y, Li L, Gong L, Liao W, Zheng P, Luo X, Wang Q, Luo M, Fu C, Li R, Xiao H. Self-assembled nano delivery system of fenugreek polysaccharides: Effects on curcumin bioavailability and molecular mechanisms. Int J Biol Macromol. 2025 Jan; 286:138294.

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Guo X, Liu H, Hou R, Chen G, Xiao H, Liu L, Ciftci ON, Liu L. Design strategies of polysaccharide, protein and lipid-based nano-delivery systems in improving the bioavailability of polyphenols and regulating gut homeostasis. Int J Biol Macromol. 2024 Dec; 283(Pt 4):137463.

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Lin Y, McClements DJ, Zhang J, Ke L, He Y, Xiao J, Cao Y, Liu X. In vitro digestive behavior of emulsifier-stabilized excipient emulsions affects the bioaccessibility of flavonoids. J Sci Food Agric. 2025 Mar 15; 105(4):2146-2157.

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Li W, Zhu X, Zhou Y, Jiang Y, Feng J, McClements DJ, Hu K. Impact of calcium-reinforcement on stability, bioavailability, and bioactivity of quercetin-loaded zein/alginate-pectin nanoparticles. J Sci Food Agric. 2025 Feb; 105(3):1771-1782.

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Zhang Z, Miao W, Ji H, Lin Q, Li X, Sang S, McClements DJ, Jin Z, Qiu C. Interaction of zein/HP-?-CD nanoparticles with digestive enzymes: Enhancing curcumin bioavailability. Food Chem. 2024 Dec 01; 460(Pt 3):140792.

View in: PubMed

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