"Endopeptidase Clp" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An ATP-dependent protease found in prokaryotes, CHLOROPLASTS, and MITOCHONDRIA. It is a soluble multisubunit complex that plays a role in the degradation of many abnormal proteins.
| Descriptor ID |
D049071
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| MeSH Number(s) |
D08.811.277.040.013.500.032.099.500 D08.811.277.040.025.024.032.099.500 D08.811.277.656.149.099.500 D08.811.277.656.300.065.500 D12.776.157.025.750.032.099.500 D12.776.575.374 D12.776.765.199.249
|
| Concept/Terms |
Endopeptidase Clp- Endopeptidase Clp
- Ti Protease
- ATP-Dependent Endoprotease Ti
- ATP Dependent Endoprotease Ti
- Endoprotease Ti, ATP-Dependent
- Protease Ti
- Clp Protease
ClpB Homolog- ClpB Homolog
- Caseinolytic Peptidase B Protein Homolog
- Mitochondrial AAA ATPase Chaperonin
- Hsp 78 Chaperone
- Chaperone, Hsp 78
ClpX Chaperone- ClpX Chaperone
- Chaperone, ClpX
- AAA(+) Chaperone ClpX
- AAA(+) Unfoldase ClpX
|
Below are MeSH descriptors whose meaning is more general than "Endopeptidase Clp".
Below are MeSH descriptors whose meaning is more specific than "Endopeptidase Clp".
This graph shows the total number of publications written about "Endopeptidase Clp" by people in this website by year, and whether "Endopeptidase Clp" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 4 | 4 |
| 2004 | 1 | 2 | 3 |
| 2005 | 1 | 1 | 2 |
| 2007 | 3 | 1 | 4 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
| 2014 | 2 | 0 | 2 |
| 2015 | 1 | 1 | 2 |
| 2016 | 1 | 2 | 3 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 2 | 3 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Endopeptidase Clp" by people in Profiles.
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Mahmoud SA, Aldikacti B, Chien P. ATP hydrolysis tunes specificity of a AAA+ protease. Cell Rep. 2022 09 20; 40(12):111405.
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Kuhlmann NJ, Doxsey D, Chien P. Cargo competition for a dimerization interface restricts and stabilizes a bacterial protease adaptor. Proc Natl Acad Sci U S A. 2021 04 27; 118(17).
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Barros BB, Mahmoud SA, Chien P, Zeinert RD. Degradation of Lon in Caulobacter crescentus. J Bacteriol. 2020 12 07; 203(1).
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Tremblay CY, Vass RH, Vachet RW, Chien P. The Cleavage Profile of Protein Substrates by ClpXP Reveals Deliberate Starts and Pauses. Biochemistry. 2020 11 10; 59(44):4294-4301.
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Szczepanowska K, Senft K, Heidler J, Herholz M, Kukat A, H?hne MN, Hofsetz E, Becker C, Kaspar S, Giese H, Zwicker K, Guerrero-Castillo S, Baumann L, Kauppila J, Rumyantseva A, M?ller S, Frese CK, Brandt U, Riemer J, Wittig I, Trifunovic A. A salvage pathway maintains highly functional respiratory complex I. Nat Commun. 2020 04 02; 11(1):1643.
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Joshi KK, Battle CM, Chien P. Polar Localization Hub Protein PopZ Restrains Adaptor-Dependent ClpXP Proteolysis in Caulobacter crescentus. J Bacteriol. 2018 10 15; 200(20).
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Joshi KK, Sutherland M, Chien P. Cargo engagement protects protease adaptors from degradation in a substrate-specific manner. J Biol Chem. 2017 06 30; 292(26):10973-10982.
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Kuhlmann NJ, Chien P. Selective adaptor dependent protein degradation in bacteria. Curr Opin Microbiol. 2017 Apr; 36:118-127.
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Liu J, Francis LI, Jonas K, Laub MT, Chien P. ClpAP is an auxiliary protease for DnaA degradation in Caulobacter crescentus. Mol Microbiol. 2016 12; 102(6):1075-1085.
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Vass RH, Zeinert RD, Chien P. Protease regulation and capacity during Caulobacter growth. Curr Opin Microbiol. 2016 12; 34:75-81.