Liver Cirrhosis

"Liver Cirrhosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.

Descriptor ID	D008103
MeSH Number(s)	C06.552.630
Concept/Terms	Liver Cirrhosis Liver Cirrhosis Cirrhosis, Liver Cirrhoses, Liver Liver Cirrhoses Hepatic Cirrhosis Cirrhoses, Hepatic Cirrhosis, Hepatic Hepatic Cirrhoses Fibrosis, Liver Fibrosis, Liver Fibroses, Liver Liver Fibroses Liver Fibrosis

Below are MeSH descriptors whose meaning is more general than "Liver Cirrhosis".

Diseases [C]
Digestive System Diseases [C06]
Liver Diseases [C06.552]
Liver Cirrhosis [C06.552.630]

Below are MeSH descriptors whose meaning is more specific than "Liver Cirrhosis".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Liver Cirrhosis" by people in this website by year, and whether "Liver Cirrhosis" was a major or minor topic of these publications.

Bar chart showing 105 publications over 25 distinct years, with a maximum of 11 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
1997	1	0	1
1999	0	1	1
2002	0	1	1
2003	0	2	2
2005	3	1	4
2006	3	0	3
2007	1	0	1
2008	3	0	3
2009	1	3	4
2011	1	0	1
2012	2	2	4
2013	11	0	11
2014	3	2	5
2015	5	2	7
2016	5	1	6
2017	3	2	5
2018	3	1	4
2019	4	0	4
2020	6	1	7
2021	3	0	3
2022	0	6	6
2023	3	7	10
2024	4	5	9
2025	2	0	2

Below are the most recent publications written about "Liver Cirrhosis" by people in Profiles.

Li W, Sparks RP, Sun C, Yang Y, Pantano L, Kirchner R, Arghiani N, Weilheimer A, Toles BJ, Chen JY, Moran SP, Barrera V, Li Z, Zhou P, Brassil ML, Wrobel D, Ho Sui SJ, Aspnes G, Schuler M, Smith J, Medoff BD, Zhou C, Boustany-Kari CM, Rippmann JF, Santos DM, Doerner JF, Mullen AC. Screening the human druggable genome identifies ABHD17B as an anti-fibrotic target in hepatic stellate cells. Nat Commun. 2025 Mar 02; 16(1):2109.

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Watson BR, Paul B, Rahman RU, Amir-Zilberstein L, Segerstolpe ?, Epstein ET, Murphy S, Geistlinger L, Lee T, Shih A, Deguine J, Xavier RJ, Moffitt JR, Mullen AC. Spatial transcriptomics of healthy and fibrotic human liver at single-cell resolution. Nat Commun. 2025 Jan 02; 16(1):319.

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Ortega-Ribera M, Zhuang Y, Babuta M, Brezani V, Joshi RS, Zsengeller Z, Thevkar Nagesh P, Wang Y, Bronson R, Szabo G. A Novel Multi-organ Male Model of Alcohol-induced Acute-on-chronic Liver Failure Reveals NET-mediated Hepatocellular Death, Which is Prevented by RIPK3 Inhibition. Cell Mol Gastroenterol Hepatol. 2025; 19(4):101446.

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Babuta M, Morel C, de Carvalho Ribeiro M, Calenda C, Ortega-Ribera M, Thevkar Nagesh P, Copeland C, Zhuang Y, Wang Y, Cho Y, Joshi R, Brezani V, Hawryluk D, Datta AA, Mehta J, Nasser I, Szabo G. Neutrophil extracellular traps activate hepatic stellate cells and monocytes via NLRP3 sensing in alcohol-induced acceleration of MASH fibrosis. Gut. 2024 Oct 07; 73(11):1854-1869.

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Friedline RH, Noh HL, Suk S, Albusharif M, Dagdeviren S, Saengnipanthkul S, Kim B, Kim AM, Kim LH, Tauer LA, Baez Torres NM, Choi S, Kim BY, Rao SD, Kasina K, Sun C, Toles BJ, Zhou C, Li Z, Benoit VM, Patel PR, Zheng DXT, Inashima K, Beaverson A, Hu X, Tran DA, Muller W, Greiner DL, Mullen AC, Lee KW, Kim JK. IFN?-IL12 axis regulates intercellular crosstalk in metabolic dysfunction-associated steatotic liver disease. Nat Commun. 2024 Jun 29; 15(1):5506.

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Taru V, Szabo G, Mehal W, Reiberger T. Inflammasomes in chronic liver disease: Hepatic injury, fibrosis progression and systemic inflammation. J Hepatol. 2024 Nov; 81(5):895-910.

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Cooper KM, Colletta A, Osorio B, Herringshaw E, Talat A, Devuni D. History of Depression is Associated With Higher Prevalence of Hepatic Encephalopathy in Patients With Advanced Liver Disease. Am J Med. 2024 09; 137(9):872-879.e2.

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Sabet A. A Phase 3 Trial of Resmetirom in NASH with Liver Fibrosis. N Engl J Med. 2024 May 02; 390(17):1632.

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Sun C, Zhou C, Daneshvar K, Ben Saad A, Kratkiewicz AJ, Toles BJ, Arghiani N, Hess A, Chen JY, Pondick JV, York SR, Li W, Moran SP, Gentile SD, Rahman RU, Li Z, Zhou P, Sparks RP, Habboub T, Kim BM, Choi MY, Affo S, Schwabe RF, Popov YV, Mullen AC. Conserved long noncoding RNA TILAM promotes liver fibrosis through interaction with PML in HSCs. Hepatology. 2025 Mar 01; 81(3):853-869.

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Min K, Yenilmez B, Kelly M, Echeverria D, Elleby M, Lifshitz LM, Raymond N, Tsagkaraki E, Harney SM, DiMarzio C, Wang H, McHugh N, Bramato B, Morrison B, Rothstein JD, Khvorova A, Czech MP. Lactate transporter MCT1 in hepatic stellate cells promotes fibrotic collagen expression in nonalcoholic steatohepatitis. Elife. 2024 Apr 02; 12.

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