A syndrome characterized by persistent or recurrent fatigue, diffuse musculoskeletal pain, sleep disturbances, and subjective cognitive impairment of 6 months duration or longer. Symptoms are not caused by ongoing exertion; are not relieved by rest; and result in a substantial reduction of previous levels of occupational, educational, social, or personal activities. Minor alterations of immune, neuroendocrine, and autonomic function may be associated with this syndrome. There is also considerable overlap between this condition and FIBROMYALGIA. (From Semin Neurol 1998;18(2):237-42; Ann Intern Med 1994 Dec 15;121(12): 953-9)

Descriptor ID	D015673
MeSH Number(s)	C02.330 C05.651.310 C10.228.440.600 C10.668.364
Concept/Terms	Fatigue Syndrome, Chronic Fatigue Syndrome, Chronic Myalgic Encephalomyelitis Encephalomyelitis, Myalgic Chronic Fatigue Syndrome Chronic Fatigue Syndromes Fatigue Syndromes, Chronic Chronic Fatigue-Fibromyalgia Syndrome Chronic Fatigue Fibromyalgia Syndrome Chronic Fatigue-Fibromyalgia Syndromes Fatigue-Fibromyalgia Syndrome, Chronic Fatigue-Fibromyalgia Syndromes, Chronic Postviral Fatigue Syndrome Infectious Mononucleosis-Like Syndrome, Chronic Infectious Mononucleosis Like Syndrome, Chronic Royal Free Disease Chronic Fatigue and Immune Dysfunction Syndrome Chronic Fatigue Disorder Chronic Fatigue Disorders Fatigue Disorder, Chronic Fatigue Disorders, Chronic Systemic Exertion Intolerance Disease Fatigue Syndrome, Postviral Fatigue Syndromes, Postviral Postviral Fatigue Syndromes

Below are MeSH descriptors whose meaning is more general than "Fatigue Syndrome, Chronic".

Below are MeSH descriptors whose meaning is related to "Fatigue Syndrome, Chronic".

Below are MeSH descriptors whose meaning is more specific than "Fatigue Syndrome, Chronic".