Long-Term Synaptic Depression
"Long-Term Synaptic Depression" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A persistent activity-dependent decrease in synaptic efficacy between NEURONS. It typically occurs following repeated low-frequency afferent stimulation, but it can be induced by other methods. Long-term depression appears to play a role in MEMORY.
| Descriptor ID |
D036881
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| MeSH Number(s) |
G11.561.638.355
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| Concept/Terms |
Long-Term Synaptic Depression- Long-Term Synaptic Depression
- Long Term Synaptic Depression
- Synaptic Depression, Long-Term
- Long-Term Depression, Physiological
- Depression, Physiological Long-Term
- Depressions, Physiological Long-Term
- Long Term Depression, Physiological
- Long-Term Depressions, Physiological
- Physiological Long-Term Depression
- Physiological Long-Term Depressions
- Long-Term Depression, Neurophysiological
- Depression, Neurophysiological Long-Term
- Depressions, Neurophysiological Long-Term
- Long Term Depression, Neurophysiological
- Long-Term Depressions, Neurophysiological
- Neurophysiological Long-Term Depression
- Neurophysiological Long-Term Depressions
- Long-Term Depression, Physiologic
- Long Term Depression, Physiologic
- Physiologic Long-Term Depression
- Long-Term Depression, Neurophysiologic
- Long Term Depression, Neurophysiologic
- Neurophysiologic Long-Term Depression
Depotentiation- Depotentiation
- Homosynaptic Depression
- Depression, Homosynaptic
|
Below are MeSH descriptors whose meaning is more general than "Long-Term Synaptic Depression".
Below are MeSH descriptors whose meaning is more specific than "Long-Term Synaptic Depression".
This graph shows the total number of publications written about "Long-Term Synaptic Depression" by people in this website by year, and whether "Long-Term Synaptic Depression" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Long-Term Synaptic Depression" by people in Profiles.
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Ji X, Martin GE. BK channels mediate dopamine inhibition of firing in a subpopulation of core nucleus accumbens medium spiny neurons. Brain Res. 2014 Nov 07; 1588:1-16.
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Ji X, Martin GE. New rules governing synaptic plasticity in core nucleus accumbens medium spiny neurons. Eur J Neurosci. 2012 Dec; 36(12):3615-27.
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Jo J, Son GH, Winters BL, Kim MJ, Whitcomb DJ, Dickinson BA, Lee YB, Futai K, Amici M, Sheng M, Collingridge GL, Cho K. Muscarinic receptors induce LTD of NMDAR EPSCs via a mechanism involving hippocalcin, AP2 and PSD-95. Nat Neurosci. 2010 Oct; 13(10):1216-24.
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Din N, Ahmad I, Ul Haq I, Elahi S, Hoessli DC, Shakoori AR. The function of GluR1 and GluR2 in cerebellar and hippocampal LTP and LTD is regulated by interplay of phosphorylation and O-GlcNAc modification. J Cell Biochem. 2010 Feb 15; 109(3):585-97.
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Ryu J, Futai K, Feliu M, Weinberg R, Sheng M. Constitutively active Rap2 transgenic mice display fewer dendritic spines, reduced extracellular signal-regulated kinase signaling, enhanced long-term depression, and impaired spatial learning and fear extinction. J Neurosci. 2008 Aug 13; 28(33):8178-88.
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Kim MJ, Futai K, Jo J, Hayashi Y, Cho K, Sheng M. Synaptic accumulation of PSD-95 and synaptic function regulated by phosphorylation of serine-295 of PSD-95. Neuron. 2007 Nov 08; 56(3):488-502.