A class of ionotropic glutamate receptors characterized by affinity for N-methyl-D-aspartate. NMDA receptors have an allosteric binding site for glycine which must be occupied for the channel to open efficiently and a site within the channel itself to which magnesium ions bind in a voltage-dependent manner. The positive voltage dependence of channel conductance and the high permeability of the conducting channel to calcium ions (as well as to monovalent cations) are important in excitotoxicity and neuronal plasticity.

Descriptor ID	D016194
MeSH Number(s)	D12.776.157.530.400.400.500.500 D12.776.543.550.450.500.200.500 D12.776.543.585.400.500.200.500 D12.776.543.750.720.200.450.400.500
Concept/Terms	Receptors, N-Methyl-D-Aspartate Receptors, N-Methyl-D-Aspartate Receptors, N Methyl D Aspartate N-Methyl-D-Aspartate Receptors N Methyl D Aspartate Receptors NMDA Receptors Receptors, N-Methylaspartate Receptors, N Methylaspartate Receptors, NMDA NMDA Receptor-Ionophore Complex NMDA Receptor Ionophore Complex N-Methylaspartate Receptors N Methylaspartate Receptors

Below are MeSH descriptors whose meaning is more general than "Receptors, N-Methyl-D-Aspartate".

Below are MeSH descriptors whose meaning is related to "Receptors, N-Methyl-D-Aspartate".

Below are MeSH descriptors whose meaning is more specific than "Receptors, N-Methyl-D-Aspartate".