Large-Conductance Calcium-Activated Potassium Channels

"Large-Conductance Calcium-Activated Potassium Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A major class of calcium activated potassium channels whose members are voltage-dependent. MaxiK channels are activated by either membrane depolarization or an increase in intracellular Ca(2+). They are key regulators of calcium and electrical signaling in a variety of tissues.

Descriptor ID	D051036
MeSH Number(s)	D12.776.157.530.400.600.150.500 D12.776.543.550.450.750.150.500 D12.776.543.585.400.750.150.500
Concept/Terms	Large-Conductance Calcium-Activated Potassium Channels Large-Conductance Calcium-Activated Potassium Channels Large Conductance Calcium Activated Potassium Channels Maxi-K Channels Maxi K Channels BK Channels MaxiK Channels Big K Channels

Below are MeSH descriptors whose meaning is more general than "Large-Conductance Calcium-Activated Potassium Channels".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Membrane Transport Proteins [D12.776.157.530]
Ion Channels [D12.776.157.530.400]
Potassium Channels [D12.776.157.530.400.600]
Potassium Channels, Calcium-Activated [D12.776.157.530.400.600.150]
Large-Conductance Calcium-Activated Potassium Channels [D12.776.157.530.400.600.150.500]
Membrane Proteins [D12.776.543]
Membrane Glycoproteins [D12.776.543.550]
Ion Channels [D12.776.543.550.450]
Potassium Channels [D12.776.543.550.450.750]
Potassium Channels, Calcium-Activated [D12.776.543.550.450.750.150]
Large-Conductance Calcium-Activated Potassium Channels [D12.776.543.550.450.750.150.500]
Membrane Transport Proteins [D12.776.543.585]
Ion Channels [D12.776.543.585.400]
Potassium Channels [D12.776.543.585.400.750]
Potassium Channels, Calcium-Activated [D12.776.543.585.400.750.150]
Large-Conductance Calcium-Activated Potassium Channels [D12.776.543.585.400.750.150.500]

Below are MeSH descriptors whose meaning is related to "Large-Conductance Calcium-Activated Potassium Channels".

Below are MeSH descriptors whose meaning is more specific than "Large-Conductance Calcium-Activated Potassium Channels".

Large-Conductance Calcium-Activated Potassium Channels
Large-Conductance Calcium-Activated Potassium Channel alpha Subunits
Large-Conductance Calcium-Activated Potassium Channel beta Subunits

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Large-Conductance Calcium-Activated Potassium Channels" by people in this website by year, and whether "Large-Conductance Calcium-Activated Potassium Channels" was a major or minor topic of these publications.

Bar chart showing 21 publications over 10 distinct years, with a maximum of 4 publications in 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	2	2
2004	0	3	3
2007	1	0	1
2008	3	0	3
2009	2	1	3
2013	1	0	1
2014	1	0	1
2015	3	1	4
2016	0	2	2
2024	0	1	1

Below are the most recent publications written about "Large-Conductance Calcium-Activated Potassium Channels" by people in Profiles.

Taylor A, Adank DN, Young PA, Quan Y, Nabit BP, Winder DG. Forced Abstinence from Volitional Ethanol Intake Drives a Vulnerable Period of Hyperexcitability in BNST-Projecting Insular Cortex Neurons. J Neurosci. 2024 01 24; 44(4).

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Vel?zquez-Marrero C, Burgos A, Garc?a JO, Palacio S, Marrero HG, Bernardo A, P?rez-Laspiur J, Rivera-Oliver M, Seale G, Treistman SN. Alcohol Regulates BK Surface Expression via Wnt/?-Catenin Signaling. J Neurosci. 2016 10 12; 36(41):10625-10639.

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Navarrete FA, Alvau A, Lee HC, Levin LR, Buck J, Leon PM, Santi CM, Krapf D, Mager J, Fissore RA, Salicioni AM, Darszon A, Visconti PE. Transient exposure to calcium ionophore enables in vitro fertilization in sterile mouse models. Sci Rep. 2016 09 15; 6:33589.

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Stival C, Puga Molina Ldel C, Paudel B, Buffone MG, Visconti PE, Krapf D. Sperm Capacitation and Acrosome Reaction in Mammalian Sperm. Adv Anat Embryol Cell Biol. 2016; 220:93-106.

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Marrero HG, Treistman SN, Lemos JR. Ethanol Effect on BK Channels is Modulated by Magnesium. Alcohol Clin Exp Res. 2015 Sep; 39(9):1671-9.

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Palacio S, Vel?zquez-Marrero C, Marrero HG, Seale GE, Yudowski GA, Treistman SN. Time-Dependent Effects of Ethanol on BK Channel Expression and Trafficking in Hippocampal Neurons. Alcohol Clin Exp Res. 2015 Sep; 39(9):1619-31.

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Stival C, La Spina FA, Bar? Graf C, Arcelay E, Arranz SE, Ferreira JJ, Le Grand S, Dzikunu VA, Santi CM, Visconti PE, Buffone MG, Krapf D. Src Kinase Is the Connecting Player between Protein Kinase A (PKA) Activation and Hyperpolarization through SLO3 Potassium Channel Regulation in Mouse Sperm. J Biol Chem. 2015 Jul 24; 290(30):18855-64.

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Oh KH, Abraham LS, Gegg C, Silvestri C, Huang YC, Alkema MJ, Furst J, Raicu D, Kim H. Presynaptic BK channel localization is dependent on the hierarchical organization of alpha-catulin and dystrobrevin and fine-tuned by CaV2 calcium channels. BMC Neurosci. 2015 Apr 24; 16:26.

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Escoffier J, Navarrete F, Haddad D, Santi CM, Darszon A, Visconti PE. Flow cytometry analysis reveals that only a subpopulation of mouse sperm undergoes hyperpolarization during capacitation. Biol Reprod. 2015 May; 92(5):121.

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Ji X, Martin GE. BK channels mediate dopamine inhibition of firing in a subpopulation of core nucleus accumbens medium spiny neurons. Brain Res. 2014 Nov 07; 1588:1-16.

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