"Mitomycins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of methylazirinopyrroloindolediones obtained from certain Streptomyces strains. They are very toxic antibiotics used as ANTINEOPLASTIC AGENTS in some solid tumors. PORFIROMYCIN and MITOMYCIN are the most useful members of the group.
| Descriptor ID |
D008937
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| MeSH Number(s) |
D02.806.400.249 D03.383.097.500 D03.633.100.473.412.249
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Mitomycins".
Below are MeSH descriptors whose meaning is more specific than "Mitomycins".
This graph shows the total number of publications written about "Mitomycins" by people in this website by year, and whether "Mitomycins" was a major or minor topic of these publications.
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Below are the most recent publications written about "Mitomycins" by people in Profiles.
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Hesketh PJ, Cooley TP, Finkel HE, Wright J, Hesketh AM. Treatment of advanced non-small cell lung cancer with cisplatin, 5-fluorouracil, and mitomycin C. Cancer. 1988 Oct 15; 62(8):1466-70.
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Fram RJ, Sullivan J, Marinus MG. Mutagenesis and repair of DNA damage caused by nitrogen mustard, N,N'-bis(2-chloroethyl)-N-nitrosourea (BCNU), streptozotocin, and mitomycin C in E. coli. Mutat Res. 1986 Nov; 166(3):299-42.
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Swain SL, Bakke A, English M, Dutton RW. Ly phenotypes and MHC recognition: the allohelper that recognizes K or D is a mature Ly123 cell. J Immunol. 1979 Dec; 123(6):2716-24.
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Swain SL, Dutton RW. Negative allogeneic effects in vitro. I. Allogeneic T cells markedly suppress the secondary antibody-forming cell response. J Immunol. 1977 Jun; 118(6):2262-8.
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Swain SL, Trefts PE, Tse HY, Dutton RW. The significance of T-B collaboration across haplotype barriers. Cold Spring Harb Symp Quant Biol. 1977; 41 Pt 2:597-609.
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Marinus MG, Morris NR. Biological function for 6-methyladenine residues in the DNA of Escherichia coli K12. J Mol Biol. 1974 May 15; 85(2):309-22.