Site-Specific DNA-Methyltransferase (Adenine-Specific)
"Site-Specific DNA-Methyltransferase (Adenine-Specific)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme responsible for producing a species-characteristic methylation pattern on adenine residues in a specific short base sequence in the host cell DNA. The enzyme catalyzes the methylation of DNA adenine in the presence of S-adenosyl-L-methionine to form DNA containing 6-methylaminopurine and S-adenosyl-L-homocysteine. EC 2.1.1.72.
| Descriptor ID |
D015265
|
| MeSH Number(s) |
D08.811.913.555.500.350.700
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| Concept/Terms |
Site-Specific DNA-Methyltransferase (Adenine-Specific)- Site-Specific DNA-Methyltransferase (Adenine-Specific)
- DNA Modification Methylases Adenine Specific
- DNA Modification Methylases (Adenine-Specific)
- Modification Methylases (Adenine-Specific)
- Site Specific Methyltransferases (Adenine Specific)
- Site-Specific Methyltransferases (Adenine-Specific)
- DNA-Adenine Methylases
- DNA Adenine Methylases
- Methylases, DNA-Adenine
- Modification Methylases (Adenine Specific)
|
Below are MeSH descriptors whose meaning is more general than "Site-Specific DNA-Methyltransferase (Adenine-Specific)".
Below are MeSH descriptors whose meaning is more specific than "Site-Specific DNA-Methyltransferase (Adenine-Specific)".
This graph shows the total number of publications written about "Site-Specific DNA-Methyltransferase (Adenine-Specific)" by people in this website by year, and whether "Site-Specific DNA-Methyltransferase (Adenine-Specific)" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2003 | 2 | 0 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 3 | 0 | 3 |
| 2007 | 3 | 0 | 3 |
| 2010 | 1 | 1 | 2 |
| 2013 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Site-Specific DNA-Methyltransferase (Adenine-Specific)" by people in Profiles.
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Campbell M, Barton IS, Roop RM, Chien P. Comparison of CcrM-dependent methylation in Caulobacter crescentus and Brucella abortus by nanopore sequencing. J Bacteriol. 2024 06 20; 206(6):e0008324.
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Mitchell AC, Javidfar B, Bicks LK, Neve R, Garbett K, Lander SS, Mirnics K, Morishita H, Wood MA, Jiang Y, Gaisler-Salomon I, Akbarian S. Longitudinal assessment of neuronal 3D genomes in mouse prefrontal cortex. Nat Commun. 2016 09 06; 7:12743.
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Shell SS, Prestwich EG, Baek SH, Shah RR, Sassetti CM, Dedon PC, Fortune SM. DNA methylation impacts gene expression and ensures hypoxic survival of Mycobacterium tuberculosis. PLoS Pathog. 2013; 9(7):e1003419.
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van Steensel B, Dekker J. Genomics tools for unraveling chromosome architecture. Nat Biotechnol. 2010 Oct; 28(10):1089-95.
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Marinus MG. DNA methylation and mutator genes in Escherichia coli K-12. Mutat Res. 2010 Oct; 705(2):71-76.
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Murphy KC, Ritchie JM, Waldor MK, L?bner-Olesen A, Marinus MG. Dam methyltransferase is required for stable lysogeny of the Shiga toxin (Stx2)-encoding bacteriophage 933W of enterohemorrhagic Escherichia coli O157:H7. J Bacteriol. 2008 Jan; 190(1):438-41.
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Broadbent SE, Balbontin R, Casadesus J, Marinus MG, van der Woude M. YhdJ, a nonessential CcrM-like DNA methyltransferase of Escherichia coli and Salmonella enterica. J Bacteriol. 2007 Jun; 189(11):4325-7.
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Campellone KG, Roe AJ, L?bner-Olesen A, Murphy KC, Magoun L, Brady MJ, Donohue-Rolfe A, Tzipori S, Gally DL, Leong JM, Marinus MG. Increased adherence and actin pedestal formation by dam-deficient enterohaemorrhagic Escherichia coli O157:H7. Mol Microbiol. 2007 Mar; 63(5):1468-81.
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Robbins-Manke JL, Zdraveski ZZ, Marinus M, Essigmann JM. Analysis of global gene expression and double-strand-break formation in DNA adenine methyltransferase- and mismatch repair-deficient Escherichia coli. J Bacteriol. 2005 Oct; 187(20):7027-37.
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Nowosielska A, Marinus MG. Cisplatin induces DNA double-strand break formation in Escherichia coli dam mutants. DNA Repair (Amst). 2005 Jul 12; 4(7):773-81.