 Immunoglobulin A, Secretory
"Immunoglobulin A, Secretory" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The principle immunoglobulin in exocrine secretions such as milk, respiratory and intestinal mucin, saliva and tears. The complete molecule (around 400 kD) is composed of two four-chain units of IMMUNOGLOBULIN A, one SECRETORY COMPONENT and one J chain (IMMUNOGLOBULIN J-CHAINS).
| Descriptor ID |
D007071
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| MeSH Number(s) |
D12.776.124.486.485.114.619.026.030 D12.776.124.790.651.114.619.026.030 D12.776.377.715.548.114.619.026.030
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| Concept/Terms |
Immunoglobulin A, Secretory- Immunoglobulin A, Secretory
- Secretory IgA
- IgA, Exocrine
- Exocrine IgA
- SIgA
- IgA, Secretory
- Secretory Immunoglobulin A
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Below are MeSH descriptors whose meaning is more general than "Immunoglobulin A, Secretory".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin A, Secretory".
This graph shows the total number of publications written about "Immunoglobulin A, Secretory" by people in this website by year, and whether "Immunoglobulin A, Secretory" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Immunoglobulin A, Secretory" by people in Profiles.
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Reboldi A, Arnon TI, Rodda LB, Atakilit A, Sheppard D, Cyster JG. IgA production requires B cell interaction with subepithelial dendritic cells in Peyer's patches. Science. 2016 May 13; 352(6287):aaf4822.
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Fouda GG, Eudailey J, Kunz EL, Amos JD, Liebl BE, Himes J, Boakye-Agyeman F, Beck K, Michaels AJ, Cohen-Wolkowiez M, Haynes BF, Reimann KA, Permar SR. Systemic administration of an HIV-1 broadly neutralizing dimeric IgA yields mucosal secretory IgA and virus neutralization. Mucosal Immunol. 2017 01; 10(1):228-237.
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Harris NL, Spoerri I, Schopfer JF, Nembrini C, Merky P, Massacand J, Urban JF, Lamarre A, Burki K, Odermatt B, Zinkernagel RM, Macpherson AJ. Mechanisms of neonatal mucosal antibody protection. J Immunol. 2006 Nov 01; 177(9):6256-62.
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Maaser C, Housley MP, Iimura M, Smith JR, Vallance BA, Finlay BB, Schreiber JR, Varki NM, Kagnoff MF, Eckmann L. Clearance of Citrobacter rodentium requires B cells but not secretory immunoglobulin A (IgA) or IgM antibodies. Infect Immun. 2004 Jun; 72(6):3315-24.
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Beyrer C, Artenstein AW, Rugpao S, Stephens H, VanCott TC, Robb ML, Rinkaew M, Birx DL, Khamboonruang C, Zimmerman PA, Nelson KE, Natpratan C. Epidemiologic and biologic characterization of a cohort of human immunodeficiency virus type 1 highly exposed, persistently seronegative female sex workers in northern Thailand. Chiang Mai HEPS Working Group. J Infect Dis. 1999 Jan; 179(1):59-67.
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