Immunoglobulin Isotypes

"Immunoglobulin Isotypes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The classes of immunoglobulins found in any species of animal. In man there are nine classes that migrate in five different groups in electrophoresis; they each consist of two light and two heavy protein chains, and each group has distinguishing structural and functional properties.

Descriptor ID	D007132
MeSH Number(s)	D12.776.124.486.485.114.619 D12.776.124.790.651.114.619 D12.776.377.715.548.114.619
Concept/Terms	Immunoglobulin Isotypes Immunoglobulin Isotypes Isotypes, Immunoglobulin Immunoglobulin Classes Classes, Immunoglobulin Antibody Classes Classes, Antibody

Below are MeSH descriptors whose meaning is more general than "Immunoglobulin Isotypes".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Blood Proteins [D12.776.124]
Immunoproteins [D12.776.124.486]
Immunoglobulins [D12.776.124.486.485]
Antibodies [D12.776.124.486.485.114]
Immunoglobulin Isotypes [D12.776.124.486.485.114.619]
Serum Globulins [D12.776.124.790]
Immunoglobulins [D12.776.124.790.651]
Antibodies [D12.776.124.790.651.114]
Immunoglobulin Isotypes [D12.776.124.790.651.114.619]
Globulins [D12.776.377]
Serum Globulins [D12.776.377.715]
Immunoglobulins [D12.776.377.715.548]
Antibodies [D12.776.377.715.548.114]
Immunoglobulin Isotypes [D12.776.377.715.548.114.619]

Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin Isotypes".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Immunoglobulin Isotypes" by people in this website by year, and whether "Immunoglobulin Isotypes" was a major or minor topic of these publications.

Bar chart showing 16 publications over 11 distinct years, with a maximum of 3 publications in 1999 and 2003

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
1997	0	1	1
1999	2	1	3
2002	0	1	1
2003	3	0	3
2007	1	0	1
2008	1	0	1
2009	1	0	1
2010	1	0	1
2012	1	1	2
2013	1	0	1

Below are the most recent publications written about "Immunoglobulin Isotypes" by people in Profiles.

Kumar S, Wuerffel R, Achour I, Lajoie B, Sen R, Dekker J, Feeney AJ, Kenter AL. Flexible ordering of antibody class switch and V(D)J joining during B-cell ontogeny. Genes Dev. 2013 Nov 15; 27(22):2439-44.

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Yu X, Duval M, Lewis C, Gawron MA, Wang R, Posner MR, Cavacini LA. Impact of IgA constant domain on HIV-1 neutralizing function of monoclonal antibody F425A1g8. J Immunol. 2013 Jan 01; 190(1):205-10.

View in: PubMed
Hasham MG, Snow KJ, Donghia NM, Branca JA, Lessard MD, Stavnezer J, Shopland LS, Mills KD. Activation-induced cytidine deaminase-initiated off-target DNA breaks are detected and resolved during S phase. J Immunol. 2012 Sep 01; 189(5):2374-82.

View in: PubMed
Stavnezer J, Bj?rkman A, Du L, Cagigi A, Pan-Hammarstr?m Q. Mapping of switch recombination junctions, a tool for studying DNA repair pathways during immunoglobulin class switching. Adv Immunol. 2010; 108:45-109.

View in: PubMed
Iweala OI, Smith DW, Matharu KS, Sada-Ovalle I, Nguyen DD, Dekruyff RH, Umetsu DT, Behar SM, Nagler CR. Vaccine-induced antibody isotypes are skewed by impaired CD4 T cell and invariant NKT cell effector responses in MyD88-deficient mice. J Immunol. 2009 Aug 15; 183(4):2252-60.

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Stavnezer J, Guikema JE, Schrader CE. Mechanism and regulation of class switch recombination. Annu Rev Immunol. 2008; 26:261-92.

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Norris HH, Peterson ME, Stebbins CC, McConchie BW, Bundoc VG, Trivedi S, Hodges MG, Anthony RM, Urban JF, Long EO, Keane-Myers AM. Inhibitory receptor gp49B regulates eosinophil infiltration during allergic inflammation. J Leukoc Biol. 2007 Dec; 82(6):1531-41.

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Kaminski DA, Stavnezer J. Stimuli that enhance IgA class switching increase histone 3 acetylation at S alpha, but poorly stimulate sequential switching from IgG2b. Eur J Immunol. 2007 Jan; 37(1):240-51.

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Stashenko P, Gon?alves RB, Lipkin B, Ficarelli A, Sasaki H, Campos-Neto A. Th1 immune response promotes severe bone resorption caused by Porphyromonas gingivalis. Am J Pathol. 2007 Jan; 170(1):203-13.

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Warraich RS, Sliwa K, Damasceno A, Carraway R, Sundrom B, Arif G, Essop R, Ansari A, Fett J, Yacoub M. Impact of pregnancy-related heart failure on humoral immunity: clinical relevance of G3-subclass immunoglobulins in peripartum cardiomyopathy. Am Heart J. 2005 Aug; 150(2):263-9.

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