"Shiga Toxin 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A toxin produced by certain pathogenic strains of ESCHERICHIA COLI such as ESCHERICHIA COLI O157. It shares 50-60% homology with SHIGA TOXIN and SHIGA TOXIN 1.
| Descriptor ID |
D022641
|
| MeSH Number(s) |
D08.811.277.450.430.700.750.750.124 D12.776.097.275.879 D23.946.123.794.124 D23.946.330.575.124
|
| Concept/Terms |
Shiga Toxin 2- Shiga Toxin 2
- Shiga Toxin 2, Escherichia coli
- Shiga-Like Toxin II
- VT2 Cytotoxin
- Cytotoxin, VT2
- SLTII
- Stx2 protein
- Vero Cytotoxin VT2
- Verotoxin 2
- Shiga Like Toxin II
- SLT-II
- SLT II
|
Below are MeSH descriptors whose meaning is more general than "Shiga Toxin 2".
Below are MeSH descriptors whose meaning is more specific than "Shiga Toxin 2".
This graph shows the total number of publications written about "Shiga Toxin 2" by people in this website by year, and whether "Shiga Toxin 2" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
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Below are the most recent publications written about "Shiga Toxin 2" by people in Profiles.
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Jandhyala DM, Ahluwalia A, Schimmel JJ, Rogers AB, Leong JM, Thorpe CM. Activation of the Classical Mitogen-Activated Protein Kinases Is Part of the Shiga Toxin-Induced Ribotoxic Stress Response and May Contribute to Shiga Toxin-Induced Inflammation. Infect Immun. 2016 01; 84(1):138-48.
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Stone SM, Thorpe CM, Ahluwalia A, Rogers AB, Obata F, Vozenilek A, Kolling GL, Kane AV, Magun BE, Jandhyala DM. Shiga toxin 2-induced intestinal pathology in infant rabbits is A-subunit dependent and responsive to the tyrosine kinase and potential ZAK inhibitor imatinib. Front Cell Infect Microbiol. 2012; 2:135.
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Murphy KC, Ritchie JM, Waldor MK, L?bner-Olesen A, Marinus MG. Dam methyltransferase is required for stable lysogeny of the Shiga toxin (Stx2)-encoding bacteriophage 933W of enterohemorrhagic Escherichia coli O157:H7. J Bacteriol. 2008 Jan; 190(1):438-41.
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Ritchie JM, Thorpe CM, Rogers AB, Waldor MK. Critical roles for stx2, eae, and tir in enterohemorrhagic Escherichia coli-induced diarrhea and intestinal inflammation in infant rabbits. Infect Immun. 2003 Dec; 71(12):7129-39.
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Mukherjee J, Chios K, Fishwild D, Hudson D, O'Donnell S, Rich SM, Donohue-Rolfe A, Tzipori S. Human Stx2-specific monoclonal antibodies prevent systemic complications of Escherichia coli O157:H7 infection. Infect Immun. 2002 Feb; 70(2):612-9.