Synaptosomal-Associated Protein 25

"Synaptosomal-Associated Protein 25" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A ubiquitous target SNARE protein that interacts with SYNTAXIN and SYNAPTOBREVIN. It is a core component of the machinery for intracellular MEMBRANE FUSION. The sequence contains 2 SNARE domains, one is the prototype for the Qb-SNARES, and the other is the prototype for the Qc-SNARES.

Descriptor ID	D050825
MeSH Number(s)	D12.776.543.512.249.500.750.500 D12.776.543.512.249.500.875.500 D12.776.543.990.775.500.750.500 D12.776.543.990.775.500.875.500
Concept/Terms	Synaptosomal-Associated Protein 25 Synaptosomal-Associated Protein 25 Synaptosomal Associated Protein 25 SNAP25 Protein SNAP-25 Protein SNAP 25 Protein SNAP-25B Protein SNAP-25B Protein SNAP 25B Protein

Below are MeSH descriptors whose meaning is more general than "Synaptosomal-Associated Protein 25".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Membrane Fusion Proteins [D12.776.543.512]
SNARE Proteins [D12.776.543.512.249]
Q-SNARE Proteins [D12.776.543.512.249.500]
Qb-SNARE Proteins [D12.776.543.512.249.500.750]
Synaptosomal-Associated Protein 25 [D12.776.543.512.249.500.750.500]
Qc-SNARE Proteins [D12.776.543.512.249.500.875]
Synaptosomal-Associated Protein 25 [D12.776.543.512.249.500.875.500]
Vesicular Transport Proteins [D12.776.543.990]
SNARE Proteins [D12.776.543.990.775]
Q-SNARE Proteins [D12.776.543.990.775.500]
Qb-SNARE Proteins [D12.776.543.990.775.500.750]
Synaptosomal-Associated Protein 25 [D12.776.543.990.775.500.750.500]
Qc-SNARE Proteins [D12.776.543.990.775.500.875]
Synaptosomal-Associated Protein 25 [D12.776.543.990.775.500.875.500]

Below are MeSH descriptors whose meaning is related to "Synaptosomal-Associated Protein 25".

Below are MeSH descriptors whose meaning is more specific than "Synaptosomal-Associated Protein 25".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Synaptosomal-Associated Protein 25" by people in this website by year, and whether "Synaptosomal-Associated Protein 25" was a major or minor topic of these publications.

Bar chart showing 8 publications over 6 distinct years, with a maximum of 3 publications in 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2009	0	1	1
2013	1	0	1
2015	1	0	1
2019	1	2	3
2024	1	0	1

Below are the most recent publications written about "Synaptosomal-Associated Protein 25" by people in Profiles.

Bhasne K, Bogoian-Mullen A, Clerico EM, Gierasch LM. The Hsc70 system maintains the synaptic SNARE protein SNAP-25 in an assembly-competent state and delays its aggregation. J Biol Chem. 2024 Dec; 300(12):108001.

View in: PubMed
Schindler SE, Li Y, Todd KW, Herries EM, Henson RL, Gray JD, Wang G, Graham DL, Shaw LM, Trojanowski JQ, Hassenstab JJ, Benzinger TLS, Cruchaga C, Jucker M, Levin J, Chhatwal JP, Noble JM, Ringman JM, Graff-Radford NR, Holtzman DM, Ladenson JH, Morris JC, Bateman RJ, Xiong C, Fagan AM. Emerging cerebrospinal fluid biomarkers in autosomal dominant Alzheimer's disease. Alzheimers Dement. 2019 05; 15(5):655-665.

View in: PubMed
Zurawski Z, Thompson Gray AD, Brady LJ, Page B, Church E, Harris NA, Dohn MR, Yim YY, Hyde K, Mortlock DP, Jones CK, Winder DG, Alford S, Hamm HE. Disabling the G??-SNARE interaction disrupts GPCR-mediated presynaptic inhibition, leading to physiological and behavioral phenotypes. Sci Signal. 2019 02 19; 12(569).

View in: PubMed
Wakai T, Fissore RA. Constitutive IP3R1-mediated Ca2+ release reduces Ca2+ store content and stimulates mitochondrial metabolism in mouse GV oocytes. J Cell Sci. 2019 02 12; 132(3).

View in: PubMed
Zulliger R, Conley SM, Mwoyosvi ML, Stuck MW, Azadi S, Naash MI. SNAREs Interact with Retinal Degeneration Slow and Rod Outer Segment Membrane Protein-1 during Conventional and Unconventional Outer Segment Targeting. PLoS One. 2015; 10(9):e0138508.

View in: PubMed
Peng L, Liu H, Ruan H, Tepp WH, Stoothoff WH, Brown RH, Johnson EA, Yao WD, Zhang SC, Dong M. Cytotoxicity of botulinum neurotoxins reveals a direct role of syntaxin 1 and SNAP-25 in neuron survival. Nat Commun. 2013; 4:1472.

View in: PubMed
Smith AK, Mick E, Faraone SV. Advances in genetic studies of attention-deficit/hyperactivity disorder. Curr Psychiatry Rep. 2009 Apr; 11(2):143-8.

View in: PubMed
Tomes CN, Michaut M, De Blas G, Visconti P, Matti U, Mayorga LS. SNARE complex assembly is required for human sperm acrosome reaction. Dev Biol. 2002 Mar 15; 243(2):326-38.

View in: PubMed
Catsicas S, Catsicas M, Keyser KT, Karten HJ, Wilson MC, Milner RJ. Differential expression of the presynaptic protein SNAP-25 in mammalian retina. J Neurosci Res. 1992 Sep; 33(1):1-9.

View in: PubMed
Catsicas S, Larhammar D, Blomqvist A, Sanna PP, Milner RJ, Wilson MC. Expression of a conserved cell-type-specific protein in nerve terminals coincides with synaptogenesis. Proc Natl Acad Sci U S A. 1991 Feb 01; 88(3):785-9.

View in: PubMed

People

Explore

Similar Concepts

Top Journals