Virulence Factors

"Virulence Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Those components of an organism that determine its capacity to cause disease but are not required for its viability per se. Two classes have been characterized: TOXINS, BIOLOGICAL and surface adhesion molecules that effect the ability of the microorganism to invade and colonize a host. (From Davis et al., Microbiology, 4th ed. p486)

Descriptor ID	D037521
MeSH Number(s)	D23.946.896
Concept/Terms	Virulence Factors Virulence Factors Factors, Virulence Pathogenicity Factors Factors, Pathogenicity

Below are MeSH descriptors whose meaning is more general than "Virulence Factors".

Chemicals and Drugs [D]
Biological Factors [D23]
Toxins, Biological [D23.946]
Virulence Factors [D23.946.896]

Below are MeSH descriptors whose meaning is related to "Virulence Factors".

Below are MeSH descriptors whose meaning is more specific than "Virulence Factors".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Virulence Factors" by people in this website by year, and whether "Virulence Factors" was a major or minor topic of these publications.

Bar chart showing 69 publications over 22 distinct years, with a maximum of 9 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	3	0	3
2004	1	1	2
2005	0	1	1
2006	3	1	4
2007	3	0	3
2008	2	2	4
2009	1	1	2
2010	1	4	5
2011	2	1	3
2012	2	4	6
2013	4	5	9
2014	3	1	4
2015	2	0	2
2016	0	2	2
2017	1	1	2
2018	0	3	3
2019	2	2	4
2020	0	2	2
2021	2	0	2
2022	0	2	2
2023	0	2	2
2024	1	1	2

Below are the most recent publications written about "Virulence Factors" by people in Profiles.

Sung K, Nawaz M, Park M, Chon J, Khan SA, Alotaibi K, Khan AA. Comprehensive Genomic Analysis of Uropathogenic E. coli: Virulence Factors, Antimicrobial Resistance, and Mobile Genetic Elements. Pathogens. 2024 Sep 13; 13(9).

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Mittal E, Prasad GVRK, Upadhyay S, Sadadiwala J, Olive AJ, Yang G, Sassetti CM, Philips JA. Mycobacterium tuberculosis virulence lipid PDIM inhibits autophagy in mice. Nat Microbiol. 2024 Nov; 9(11):2970-2984.

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Mirza Z, Walhout AJM, Ambros V. A bacterial pathogen induces developmental slowing by high reactive oxygen species and mitochondrial dysfunction in Caenorhabditis elegans. Cell Rep. 2023 10 31; 42(10):113189.

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Sephton-Clark P, McConnell SA, Grossman N, Baker RP, Dragotakes Q, Fan Y, Fu MS, Gerbig G, Greengo S, Hardwick JM, Kulkarni M, Levitz SM, Nosanchuk JD, Shoham S, Smith DFQ, Stempinski P, Timp W, Wear MP, Cuomo CA, Casadevall A. Similar evolutionary trajectories in an environmental Cryptococcus neoformans isolate after human and murine infection. Proc Natl Acad Sci U S A. 2023 01 10; 120(2):e2217111120.

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Sitaram A, Yin Y, Zamaitis T, Zhang B, Aroian RV. A Caenorhabditis elegans nck-1 and filamentous actin-regulating protein pathway mediates a key cellular defense against bacterial pore-forming proteins. PLoS Pathog. 2022 11; 18(11):e1010656.

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Burle-Caldas GA, Dos Santos NSA, de Castro JT, Mugge FLB, Grazielle-Silva V, Oliveira AER, Pereira MCA, Reis-Cunha JL, Dos Santos AC, Gomes DA, Bartholomeu DC, Moretti NS, Schenkman S, Gazzinelli RT, Teixeira SMR. Disruption of Active Trans-Sialidase Genes Impairs Egress from Mammalian Host Cells and Generates Highly Attenuated Trypanosoma cruzi Parasites. mBio. 2022 02 22; 13(1):e0347821.

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Wu T, Gagnon A, McGourty K, DosSantos R, Chanetsa L, Zhang B, Bello D, Kelleher SL. Zinc Exposure Promotes Commensal-to-Pathogen Transition in Pseudomonas aeruginosa Leading to Mucosal Inflammation and Illness in Mice. Int J Mol Sci. 2021 Dec 11; 22(24).

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Maroney MJ, Ciurli S. Nickel as a virulence factor in the Class I bacterial carcinogen, Helicobacter pylori. Semin Cancer Biol. 2021 11; 76:143-155.

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Vasquez-Rifo A, Ricci EP, Ambros V. Pseudomonas aeruginosa cleaves the decoding center of Caenorhabditis elegans ribosomes. PLoS Biol. 2020 12; 18(12):e3000969.

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Oliveira AER, Pereira MCA, Belew AT, Ferreira LRP, Pereira LMN, Neves EGA, Nunes MDCP, Burleigh BA, Dutra WO, El-Sayed NM, Gazzinelli RT, Teixeira SMR. Gene expression network analyses during infection with virulent and avirulent Trypanosoma cruzi?strains unveil a role for fibroblasts in neutrophil recruitment and activation. PLoS Pathog. 2020 08; 16(8):e1008781.

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