Fatty Acid Synthase, Type I
"Fatty Acid Synthase, Type I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Animal form of fatty acid synthase which is encoded by a single gene and consists of seven catalytic domains and is functional as a homodimer. It is overexpressed in some NEOPLASMS and is a target in humans of some ANTINEOPLASTIC AGENTS and some ANTI-OBESITY AGENTS.
| Descriptor ID |
D054890
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| MeSH Number(s) |
D08.811.277.352.897.387.100 D08.811.520.241.300.287.099 D08.811.641.758 D08.811.682.047.820.196.500.099 D08.811.913.050.134.029.500.100 D08.811.913.050.170.500.100
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Fatty Acid Synthase, Type I".
Below are MeSH descriptors whose meaning is more specific than "Fatty Acid Synthase, Type I".
This graph shows the total number of publications written about "Fatty Acid Synthase, Type I" by people in this website by year, and whether "Fatty Acid Synthase, Type I" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Fatty Acid Synthase, Type I" by people in Profiles.
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Guilherme A, Pedersen DJ, Henriques F, Bedard AH, Henchey E, Kelly M, Morgan DA, Rahmouni K, Czech MP. Neuronal modulation of brown adipose activity through perturbation of white adipocyte lipogenesis. Mol Metab. 2018 10; 16:116-125.
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Negrin KA, Roth Flach RJ, DiStefano MT, Matevossian A, Friedline RH, Jung D, Kim JK, Czech MP. IL-1 signaling in obesity-induced hepatic lipogenesis and steatosis. PLoS One. 2014; 9(9):e107265.
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Heinrich G, Ghosh S, Deangelis AM, Schroeder-Gloeckler JM, Patel PR, Castaneda TR, Jeffers S, Lee AD, Jung DY, Zhang Z, Opland DM, Myers MG, Kim JK, Najjar SM. Carcinoembryonic antigen-related cell adhesion molecule 2 controls energy balance and peripheral insulin action in mice. Gastroenterology. 2010 Aug; 139(2):644-52, 652.e1.