Spectrometry, Mass, Electrospray Ionization
"Spectrometry, Mass, Electrospray Ionization" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mass spectrometry technique used for analysis of nonvolatile compounds such as proteins and macromolecules. The technique involves preparing electrically charged droplets from analyte molecules dissolved in solvent. The electrically charged droplets enter a vacuum chamber where the solvent is evaporated. Evaporation of solvent reduces the droplet size, thereby increasing the coulombic repulsion within the droplet. As the charged droplets get smaller, the excess charge within them causes them to disintegrate and release analyte molecules. The volatilized analyte molecules are then analyzed by mass spectrometry.
| Descriptor ID |
D021241
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| MeSH Number(s) |
E05.196.566.600
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Spectrometry, Mass, Electrospray Ionization".
Below are MeSH descriptors whose meaning is more specific than "Spectrometry, Mass, Electrospray Ionization".
This graph shows the total number of publications written about "Spectrometry, Mass, Electrospray Ionization" by people in this website by year, and whether "Spectrometry, Mass, Electrospray Ionization" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 3 | 4 |
| 2010 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Spectrometry, Mass, Electrospray Ionization" by people in Profiles.
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Peng T, Nagy G, Trinidad JC, Jackson JM, Pohl NLB. A High-Throughput Mass-Spectrometry-Based Assay for Identifying the Biochemical Functions of Putative Glycosidases. Chembiochem. 2017 12 05; 18(23):2306-2311.
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Canterbury JD, Merrihew GE, MacCoss MJ, Goodlett DR, Shaffer SA. Comparison of data acquisition strategies on quadrupole ion trap instrumentation for shotgun proteomics. J Am Soc Mass Spectrom. 2014 Dec; 25(12):2048-59.
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Heron SR, Wilson R, Shaffer SA, Goodlett DR, Cooper JM. Surface acoustic wave nebulization of peptides as a microfluidic interface for mass spectrometry. Anal Chem. 2010 May 15; 82(10):3985-9.
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Boxer SG, Kraft ML, Weber PK. Advances in imaging secondary ion mass spectrometry for biological samples. Annu Rev Biophys. 2009; 38:53-74.
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Jones JW, Shaffer SA, Ernst RK, Goodlett DR, Turecek F. Determination of pyrophosphorylated forms of lipid A in Gram-negative bacteria using a multivaried mass spectrometric approach. Proc Natl Acad Sci U S A. 2008 Sep 02; 105(35):12742-7.
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Scherl A, Tsai YS, Shaffer SA, Goodlett DR. Increasing information from shotgun proteomic data by accounting for misassigned precursor ion masses. Proteomics. 2008 Jul; 8(14):2791-7.
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Scherl A, Shaffer SA, Taylor GK, Hernandez P, Appel RD, Binz PA, Goodlett DR. On the benefits of acquiring peptide fragment ions at high measured mass accuracy. J Am Soc Mass Spectrom. 2008 Jun; 19(6):891-901.
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Scherl A, Shaffer SA, Taylor GK, Kulasekara HD, Miller SI, Goodlett DR. Genome-specific gas-phase fractionation strategy for improved shotgun proteomic profiling of proteotypic peptides. Anal Chem. 2008 Feb 15; 80(4):1182-91.
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Chellappan S, Kiran Kumar Reddy GS, Ali A, Nalam MN, Anjum SG, Cao H, Kairys V, Fernandes MX, Altman MD, Tidor B, Rana TM, Schiffer CA, Gilson MK. Design of mutation-resistant HIV protease inhibitors with the substrate envelope hypothesis. Chem Biol Drug Des. 2007 May; 69(5):298-313.
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Shaffer SA, Harvey MD, Goodlett DR, Ernst RK. Structural heterogeneity and environmentally regulated remodeling of Francisella tularensis subspecies novicida lipid A characterized by tandem mass spectrometry. J Am Soc Mass Spectrom. 2007 Jun; 18(6):1080-92.