Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
"Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mass spectrometric technique that is used for the analysis of large biomolecules. Analyte molecules are embedded in an excess matrix of small organic molecules that show a high resonant absorption at the laser wavelength used. The matrix absorbs the laser energy, thus inducing a soft disintegration of the sample-matrix mixture into free (gas phase) matrix and analyte molecules and molecular ions. In general, only molecular ions of the analyte molecules are produced, and almost no fragmentation occurs. This makes the method well suited for molecular weight determinations and mixture analysis.
| Descriptor ID |
D019032
|
| MeSH Number(s) |
E05.196.566.755
|
| Concept/Terms |
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization- Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
- Mass Spectrometry, Matrix-Assisted Laser Desorption-Ionization
- Mass Spectrometry, Matrix Assisted Laser Desorption Ionization
- Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
- Matrix Assisted Laser Desorption Ionization Mass Spectrometry
- MALDI
- Spectroscopy, Mass, Matrix-Assisted Laser Desorption-Ionization
- MS-MALD
- MALD-MS
- MALDI-MS
- MALDI MS
- Laser Desorption-Ionization Mass Spectrometry, Matrix-Assisted
- Laser Desorption Ionization Mass Spectrometry, Matrix Assisted
- Mass Spectroscopy, Matrix-Assisted Laser Desorption-Ionization
- Mass Spectroscopy, Matrix Assisted Laser Desorption Ionization
|
Below are MeSH descriptors whose meaning is more general than "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization".
Below are MeSH descriptors whose meaning is more specific than "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization".
This graph shows the total number of publications written about "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization" by people in this website by year, and whether "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 2 | 3 |
| 1998 | 0 | 2 | 2 |
| 2002 | 1 | 1 | 2 |
| 2003 | 0 | 1 | 1 |
| 2005 | 1 | 6 | 7 |
| 2006 | 1 | 1 | 2 |
| 2007 | 2 | 4 | 6 |
| 2008 | 1 | 8 | 9 |
| 2009 | 0 | 5 | 5 |
| 2010 | 1 | 4 | 5 |
| 2011 | 0 | 3 | 3 |
| 2012 | 1 | 2 | 3 |
| 2013 | 2 | 1 | 3 |
| 2014 | 2 | 1 | 3 |
| 2015 | 1 | 2 | 3 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 2 | 3 |
| 2021 | 1 | 4 | 5 |
| 2025 | 2 | 0 | 2 |
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click here.
Below are the most recent publications written about "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization" by people in Profiles.
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Rampal A, Peyton SR, Vachet RW. MALDI mass spectrometry imaging of extracellular matrix proteins. Analyst. 2025 Jul 21; 150(15):3247-3256.
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Rampal A, de la Fuente IF, Vu NK, Doungchawee J, Ranjan U, Peyton SR, Vachet RW. Decellularization and Enzymatic Digestion Methods to Enhance ECM Protein Detection via MALDI-MS Imaging. Anal Chem. 2025 Jan 14; 97(1):886-893.
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Matsuoka Y, Takahashi M, Sugiura Y, Izumi Y, Nishiyama K, Nishida M, Suematsu M, Bamba T, Yamada KI. Structural library and visualization of endogenously oxidized phosphatidylcholines using mass spectrometry-based techniques. Nat Commun. 2021 11 03; 12(1):6339.
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Foureau D, Bhutani M, Guo F, Rigby K, Leonidas M, Tjaden E, Fox A, Atrash S, Paul B, Voorhees PM, Usmani SZ. Comparison of mass spectrometry and flow cytometry in measuring minimal residual disease in multiple myeloma. Cancer Med. 2021 10; 10(20):6933-6936.
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Sikora KN, Castellanos-Garc?a LJ, Hardie JM, Liu Y, Farkas ME, Rotello VM, Vachet RW. Nanodelivery vehicles induce remote biochemical changes in vivo. Nanoscale. 2021 Aug 07; 13(29):12623-12633.
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Chaudhuri S, Fowler MJ, Baker C, Stopka SA, Regan MS, Sablatura L, Broughton CW, Knight BE, Stabenfeldt SE, Agar NYR, Sirianni RW. ?-Cyclodextrin-poly (?-Amino Ester) Nanoparticles Are a Generalizable Strategy for High Loading and Sustained Release of HDAC Inhibitors. ACS Appl Mater Interfaces. 2021 May 12; 13(18):20960-20973.
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Murray DL, Puig N, Kristinsson S, Usmani SZ, Dispenzieri A, Bianchi G, Kumar S, Chng WJ, Hajek R, Paiva B, Waage A, Rajkumar SV, Durie B. Mass spectrometry for the evaluation of monoclonal proteins in multiple myeloma and related disorders: an International Myeloma Working Group Mass Spectrometry Committee Report. Blood Cancer J. 2021 02 01; 11(2):24.
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Hadjadj L, Syed MA, Bushra J, Abbasi SA, Rolain JM. Emergence of Vancomycin-Resistant Enterococcus faecium ST 80 in Pakistan. Surg Infect (Larchmt). 2019 Sep; 20(6):524-525.
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Cormier N, McGlone JJ, Leszyk J, Hardy DM. Immunocontraceptive target repertoire defined by systematic identification of sperm membrane alloantigens in a single species. PLoS One. 2018; 13(1):e0190891.
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Homyak CC, Fernandez A, Touve MA, Zhao B, Anson F, Hardy JA, Vachet RW, Gianneschi NC, Ross JL, Thayumanavan S. Lipogels for Encapsulation of Hydrophilic Proteins and Hydrophobic Small Molecules. Biomacromolecules. 2018 01 08; 19(1):132-140.