Macular Degeneration

"Macular Degeneration" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Degenerative changes in the RETINA usually of older adults which results in a loss of vision in the center of the visual field (the MACULA LUTEA) because of damage to the retina. It occurs in dry and wet forms.

Descriptor ID	D008268
MeSH Number(s)	C11.768.585.439
Concept/Terms	Macular Degeneration Macular Degeneration Degeneration, Macular Degenerations, Macular Macular Degenerations Age-Related Maculopathies Age Related Maculopathies Macular Degeneration, Age-Related Macular Dystrophy Dystrophies, Macular Dystrophy, Macular Macular Dystrophies Maculopathies, Age-Related Maculopathies, Age Related Maculopathy, Age-Related Maculopathy, Age Related Age-Related Macular Degeneration Age Related Macular Degeneration Age-Related Macular Degenerations Degeneration, Age-Related Macular Degenerations, Age-Related Macular Macular Degenerations, Age-Related Age-Related Maculopathy Age Related Maculopathy

Below are MeSH descriptors whose meaning is more general than "Macular Degeneration".

Diseases [C]
Eye Diseases [C11]
Retinal Diseases [C11.768]
Retinal Degeneration [C11.768.585]
Macular Degeneration [C11.768.585.439]

Below are MeSH descriptors whose meaning is related to "Macular Degeneration".

Below are MeSH descriptors whose meaning is more specific than "Macular Degeneration".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Macular Degeneration" by people in this website by year, and whether "Macular Degeneration" was a major or minor topic of these publications.

Bar chart showing 165 publications over 29 distinct years, with a maximum of 13 publications in 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	2	0	2
1997	4	0	4
1999	4	0	4
2000	3	0	3
2001	5	2	7
2002	2	0	2
2003	5	1	6
2004	4	0	4
2005	5	0	5
2006	8	0	8
2007	10	0	10
2008	8	1	9
2009	4	0	4
2010	8	1	9
2011	11	2	13
2012	8	1	9
2013	6	0	6
2014	5	2	7
2015	6	2	8
2016	8	1	9
2017	3	1	4
2018	2	0	2
2019	1	1	2
2020	7	0	7
2021	7	0	7
2022	4	0	4
2023	6	0	6
2024	2	1	3
2025	1	0	1

Below are the most recent publications written about "Macular Degeneration" by people in Profiles.

Cheng SY, Giguere D, Silverstein I, Conza A, Seddon JM, Kim S, Iwata T, Mueller C, Punzo C. Role of alpha-1 antitrypsin in Bruch's membrane integrity. Sci Rep. 2025 Apr 10; 15(1):12223.

View in: PubMed
Seddon JM, De D, Rosner B. The role of nutritional factors in transitioning between early, mid, and late stages of age-related macular degeneration: prospective longitudinal analysis. Am J Clin Nutr. 2024 Dec; 120(6):1387-1398.

View in: PubMed
Brown EE, Guy AA, Holroyd NA, Sweeney PW, Gourmet L, Coleman H, Walsh C, Markaki AE, Shipley R, Rajendram R, Walker-Samuel S. Physics-informed deep generative learning for quantitative assessment of the retina. Nat Commun. 2024 Aug 10; 15(1):6859.

View in: PubMed
Munzar R, Roh S, Ramsey DJ. Factors associated with loss to follow-up in patients with advanced age-related macular degeneration: A telehealth recall initiative. Ophthalmic Physiol Opt. 2024 May; 44(3):626-633.

View in: PubMed
Archambault SD, Nichols MM, McCullum JC, Zhang Y, Steinberger EE, Ramsey DJ. Patient adherence to therapy after switch to aflibercept from bevacizumab or ranibizumab for treatment-refractory neovascular age-related macular degeneration. Indian J Ophthalmol. 2024 Jan 01; 72(Suppl 1):S101-S105.

View in: PubMed
Heier JS, Lad EM, Holz FG, Rosenfeld PJ, Guymer RH, Boyer D, Grossi F, Baumal CR, Korobelnik JF, Slakter JS, Waheed NK, Metlapally R, Pearce I, Steinle N, Francone AA, Hu A, Lally DR, Deschatelets P, Francois C, Bliss C, Staurenghi G, Mon?s J, Singh RP, Ribeiro R, Wykoff CC. Pegcetacoplan for the treatment of geographic atrophy secondary to age-related macular degeneration (OAKS and DERBY): two multicentre, randomised, double-masked, sham-controlled, phase 3 trials. Lancet. 2023 10 21; 402(10411):1434-1448.

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Seddon JM, De D, Rosner B. Family History of Age-Related Macular Degeneration and Genetics Predict Progression to Advanced Age-Related Macular Degeneration Adjusting for Macular Status, Demographic, and Lifestyle Factors. Am J Ophthalmol. 2023 11; 255:74-86.

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Akkan Aydogmus FS, Onwuka O, Saddemi J, Lasalle CC, Ramsey DJ. Second eyes to develop neovascular age-related macular degeneration have fewer symptoms and better one-year visual outcomes. BMC Ophthalmol. 2023 Jul 07; 23(1):303.

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Patel SS, Lally DR, Hsu J, Wykoff CC, Eichenbaum D, Heier JS, Jaffe GJ, Westby K, Desai D, Zhu L, Khanani AM. Avacincaptad pegol for geographic atrophy secondary to age-related macular degeneration: 18-month findings from the GATHER1 trial. Eye (Lond). 2023 12; 37(17):3551-3557.

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Moradi M, Chen Y, Du X, Seddon JM. Deep ensemble learning for automated non-advanced AMD classification using optimized retinal layer segmentation and SD-OCT scans. Comput Biol Med. 2023 03; 154:106512.

View in: PubMed

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