Macular Degeneration

"Macular Degeneration" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Degenerative changes in the RETINA usually of older adults which results in a loss of vision in the center of the visual field (the MACULA LUTEA) because of damage to the retina. It occurs in dry and wet forms.

Descriptor ID	D008268
MeSH Number(s)	C11.768.585.439
Concept/Terms	Macular Degeneration Macular Degeneration Degeneration, Macular Degenerations, Macular Macular Degenerations Age-Related Maculopathies Age Related Maculopathies Macular Degeneration, Age-Related Macular Dystrophy Dystrophies, Macular Dystrophy, Macular Macular Dystrophies Maculopathies, Age-Related Maculopathies, Age Related Maculopathy, Age-Related Maculopathy, Age Related Age-Related Macular Degeneration Age Related Macular Degeneration Age-Related Macular Degenerations Degeneration, Age-Related Macular Degenerations, Age-Related Macular Macular Degenerations, Age-Related Age-Related Maculopathy Age Related Maculopathy

Below are MeSH descriptors whose meaning is more general than "Macular Degeneration".

Diseases [C]
Eye Diseases [C11]
Retinal Diseases [C11.768]
Retinal Degeneration [C11.768.585]
Macular Degeneration [C11.768.585.439]

Below are MeSH descriptors whose meaning is related to "Macular Degeneration".

Below are MeSH descriptors whose meaning is more specific than "Macular Degeneration".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Macular Degeneration" by people in this website by year, and whether "Macular Degeneration" was a major or minor topic of these publications.

Bar chart showing 144 publications over 28 distinct years, with a maximum of 12 publications in 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	2	0	2
1996	2	0	2
1997	4	0	4
1999	4	0	4
2000	3	0	3
2001	3	1	4
2002	2	0	2
2003	5	1	6
2004	3	0	3
2005	5	0	5
2006	8	0	8
2007	8	0	8
2008	8	0	8
2009	4	0	4
2010	8	1	9
2011	10	2	12
2012	8	1	9
2013	6	0	6
2014	4	0	4
2015	6	2	8
2016	7	1	8
2017	3	0	3
2018	2	0	2
2019	1	1	2
2020	6	0	6
2021	5	0	5
2022	4	0	4
2023	3	0	3

Below are the most recent publications written about "Macular Degeneration" by people in Profiles.

Heier JS, Lad EM, Holz FG, Rosenfeld PJ, Guymer RH, Boyer D, Grossi F, Baumal CR, Korobelnik JF, Slakter JS, Waheed NK, Metlapally R, Pearce I, Steinle N, Francone AA, Hu A, Lally DR, Deschatelets P, Francois C, Bliss C, Staurenghi G, Mon?s J, Singh RP, Ribeiro R, Wykoff CC. Pegcetacoplan for the treatment of geographic atrophy secondary to age-related macular degeneration (OAKS and DERBY): two multicentre, randomised, double-masked, sham-controlled, phase 3 trials. Lancet. 2023 10 21; 402(10411):1434-1448.

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Seddon JM, De D, Rosner B. Family History of Age-Related Macular Degeneration and Genetics Predict Progression to Advanced Age-Related Macular Degeneration Adjusting for Macular Status, Demographic, and Lifestyle Factors. Am J Ophthalmol. 2023 Nov; 255:74-86.

View in: PubMed
Moradi M, Chen Y, Du X, Seddon JM. Deep ensemble learning for automated non-advanced AMD classification using optimized retinal layer segmentation and SD-OCT scans. Comput Biol Med. 2023 03; 154:106512.

View in: PubMed
Java A, Pozzi N, Schroeder MC, Hu Z, Huan T, Seddon JM, Atkinson J. Functional analysis of rare genetic variants in complement factor I in advanced age-related macular degeneration. Hum Mol Genet. 2022 10 28; 31(21):3683-3693.

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Kim JE, Tomkins-Netzer O, Elman MJ, Lally DR, Goldstein M, Goldenberg D, Shulman S, Benyamini G, Loewenstein A. Evaluation of a self-imaging SD-OCT system designed for remote home monitoring. BMC Ophthalmol. 2022 Jun 10; 22(1):261.

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Garc?a-Layana A, L?pez-G?lvez M, Garc?a-Arum? J, Arias L, Gea-S?nchez A, Mar?n-M?ndez JJ, Sayar-Beristain O, Sedano-Gil G, Aslam TM, Minnella AM, Ib??ez IL, de Dios Hern?ndez JM, Seddon JM. A Screening Tool for Self-Evaluation of Risk for Age-Related Macular Degeneration: Validation in a Spanish Population. Transl Vis Sci Technol. 2022 06 01; 11(6):23.

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Lally DR, Hill L, Amador-Patarroyo MJ. Subretinal Fluid Resolution and Visual Acuity in Patients with Neovascular Age-Related Macular Degeneration: A HARBOR Post Hoc Analysis. Ophthalmol Retina. 2022 11; 6(11):1054-1060.

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Choi H, Cloutier A, Lally D. PRPH2-Associated Macular Dystrophy in 4 Family Members with a Novel Mutation. Ophthalmic Genet. 2022 04; 43(2):235-239.

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Cheng SY, Luo Y, Malachi A, Ko J, Su Q, Xie J, Tian B, Lin H, Ke X, Zheng Q, Tai PWL, Gao G, Punzo C. Low-Dose Recombinant Adeno-Associated Virus-Mediated Inhibition of Vascular Endothelial Growth Factor Can Treat Neovascular Pathologies Without Inducing Retinal Vasculitis. Hum Gene Ther. 2021 07; 32(13-14):649-666.

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McMahon O, Hallam TM, Patel S, Harris CL, Menny A, Zelek WM, Widjajahakim R, Java A, Cox TE, Tzoumas N, Steel DHW, Shuttleworth VG, Smith-Jackson K, Brocklebank V, Griffiths H, Cree AJ, Atkinson JP, Lotery AJ, Bubeck D, Morgan BP, Marchbank KJ, Seddon JM, Kavanagh D. The rare C9 P167S risk variant for age-related macular degeneration increases polymerization of the terminal component of the complement cascade. Hum Mol Genet. 2021 06 17; 30(13):1188-1199.

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